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Q08530 (BTR_BORPE) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 89. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Transcriptional regulatory protein btr
Gene names
Name:btr
Ordered Locus Names:BP1197
OrganismBordetella pertussis (strain Tohama I / ATCC BAA-589 / NCTC 13251) [Reference proteome] [HAMAP]
Taxonomic identifier257313 [NCBI]
Taxonomic lineageBacteriaProteobacteriaBetaproteobacteriaBurkholderialesAlcaligenaceaeBordetella

Protein attributes

Sequence length242 AA.
Sequence statusComplete.
Protein existencePredicted

General annotation (Comments)

Function

May regulate gene expression in response to changes in oxygen levels or to changes in the redox potential of the bacterial environment.

Sequence similarities

Contains 1 cyclic nucleotide-binding domain.

Contains 1 HTH crp-type DNA-binding domain.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 242242Transcriptional regulatory protein btr
PRO_0000100143

Regions

Domain158 – 23174HTH crp-type
DNA binding191 – 21020H-T-H motif Potential

Experimental info

Sequence conflict27 – 6438GMPAN…DAVYG → ACLPTKSRNWTNSSRRPCAW SAAKRSTNSTIPWSRLR in AAC36850. Ref.1
Sequence conflict961D → V in AAC36850. Ref.1
Sequence conflict174 – 18714RYAAL…TEFVL → ATRRSAIRRPNSCV in AAC36850. Ref.1
Sequence conflict2231R → A in AAC36850. Ref.1

Sequences

Sequence LengthMass (Da)Tools
Q08530 [UniParc].

Last modified September 19, 2003. Version 2.
Checksum: CD07103C2AFDAC12

FASTA24227,130
        10         20         30         40         50         60 
MQRRVPLSPD AAHCSSCMLG HVCVPVGMPA NEVEKLDELV KERVRVERGK TLYELDDPLD 

        70         80         90        100        110        120 
AVYGVRFGSL KTQLEDSSGQ LQITGFHLPG EIVGLDGMIE SKHVSSAVAL EDSEVCVIRL 

       130        140        150        160        170        180 
PEIDRVSTQL PSLQQQFRRL MSREITRSHQ MLATVGAMRS EQRLAAFLLN LSQRYAALGY 

       190        200        210        220        230        240 
SSTEFVLRMS REEIGNYLGL TLETVSRLFS RFGREGLIRI NQREVRLIDL PGLKQLIGQE 


SC 

« Hide

References

« Hide 'large scale' references
[1]"Cloning and characterization of btr, a Bordetella pertussis gene encoding an FNR-like transcriptional regulator."
Bannan J.D., Moran M.J., Macinnnes J.I., Soltes G.A., Friedman R.L.
J. Bacteriol. 175:7228-7235(1993) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: BP504.
[2]"Comparative analysis of the genome sequences of Bordetella pertussis, Bordetella parapertussis and Bordetella bronchiseptica."
Parkhill J., Sebaihia M., Preston A., Murphy L.D., Thomson N.R., Harris D.E., Holden M.T.G., Churcher C.M., Bentley S.D., Mungall K.L., Cerdeno-Tarraga A.-M., Temple L., James K.D., Harris B., Quail M.A., Achtman M., Atkin R., Baker S. expand/collapse author list , Basham D., Bason N., Cherevach I., Chillingworth T., Collins M., Cronin A., Davis P., Doggett J., Feltwell T., Goble A., Hamlin N., Hauser H., Holroyd S., Jagels K., Leather S., Moule S., Norberczak H., O'Neil S., Ormond D., Price C., Rabbinowitsch E., Rutter S., Sanders M., Saunders D., Seeger K., Sharp S., Simmonds M., Skelton J., Squares R., Squares S., Stevens K., Unwin L., Whitehead S., Barrell B.G., Maskell D.J.
Nat. Genet. 35:32-40(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Tohama I / ATCC BAA-589 / NCTC 13251.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
L20602 Unassigned DNA. Translation: AAC36850.1.
BX640414 Genomic DNA. Translation: CAE41493.1.
PIRA49926.
RefSeqNP_879971.1. NC_002929.2.

3D structure databases

ProteinModelPortalQ08530.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING257313.BP1197.

Proteomic databases

PRIDEQ08530.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAE41493; CAE41493; BP1197.
GeneID2667591.
KEGGbpe:BP1197.
PATRIC21155580. VBIBorPer7866_1289.

Phylogenomic databases

eggNOGCOG0664.
HOGENOMHOG000186461.
KOK01420.
OMAVREHGVM.
OrthoDBEOG6RVFWF.

Enzyme and pathway databases

BioCycBPER257313:BP1197-MONOMER.

Family and domain databases

Gene3D1.10.10.10. 1 hit.
2.60.120.10. 1 hit.
InterProIPR018490. cNMP-bd-like.
IPR000595. cNMP-bd_dom.
IPR012318. HTH_CRP_2.
IPR014710. RmlC-like_jellyroll.
IPR001808. Tscrpt_reg_HTH_Crp.
IPR018335. Tscrpt_reg_HTH_Crp-type_CS.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamPF00027. cNMP_binding. 1 hit.
PF00325. Crp. 1 hit.
[Graphical view]
PRINTSPR00034. HTHCRP.
SMARTSM00100. cNMP. 1 hit.
SM00419. HTH_CRP. 1 hit.
[Graphical view]
SUPFAMSSF51206. SSF51206. 1 hit.
PROSITEPS00042. HTH_CRP_1. 1 hit.
PS51063. HTH_CRP_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameBTR_BORPE
AccessionPrimary (citable) accession number: Q08530
Entry history
Integrated into UniProtKB/Swiss-Prot: October 1, 1994
Last sequence update: September 19, 2003
Last modified: May 14, 2014
This is version 89 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families