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Protein

Transcriptional regulatory protein btr

Gene

btr

Organism
Bordetella pertussis (strain Tohama I / ATCC BAA-589 / NCTC 13251)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

May regulate gene expression in response to changes in oxygen levels or to changes in the redox potential of the bacterial environment.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi191 – 210H-T-H motifPROSITE-ProRule annotationAdd BLAST20

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-binding
Biological processTranscription, Transcription regulation

Names & Taxonomyi

Protein namesi
Recommended name:
Transcriptional regulatory protein btr
Gene namesi
Name:btr
Ordered Locus Names:BP1197
OrganismiBordetella pertussis (strain Tohama I / ATCC BAA-589 / NCTC 13251)
Taxonomic identifieri257313 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesAlcaligenaceaeBordetella
Proteomesi
  • UP000002676 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001001431 – 242Transcriptional regulatory protein btrAdd BLAST242

Proteomic databases

PRIDEiQ08530.

Interactioni

Protein-protein interaction databases

STRINGi257313.BP1197.

Structurei

3D structure databases

ProteinModelPortaliQ08530.
SMRiQ08530.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini158 – 231HTH crp-typePROSITE-ProRule annotationAdd BLAST74

Phylogenomic databases

eggNOGiENOG4105DS0. Bacteria.
COG0664. LUCA.
HOGENOMiHOG000186461.
KOiK01420.
OMAiAEVCVMP.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
2.60.120.10. 1 hit.
InterProiView protein in InterPro
IPR018490. cNMP-bd-like.
IPR000595. cNMP-bd_dom.
IPR012318. HTH_CRP.
IPR014710. RmlC-like_jellyroll.
IPR018335. Tscrpt_reg_HTH_Crp-type_CS.
IPR011991. WHTH_DNA-bd_dom.
PfamiView protein in Pfam
PF00027. cNMP_binding. 1 hit.
PF13545. HTH_Crp_2. 1 hit.
PRINTSiPR00034. HTHCRP.
SMARTiView protein in SMART
SM00100. cNMP. 1 hit.
SM00419. HTH_CRP. 1 hit.
SUPFAMiSSF46785. SSF46785. 1 hit.
SSF51206. SSF51206. 1 hit.
PROSITEiView protein in PROSITE
PS00042. HTH_CRP_1. 1 hit.
PS51063. HTH_CRP_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q08530-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQRRVPLSPD AAHCSSCMLG HVCVPVGMPA NEVEKLDELV KERVRVERGK
60 70 80 90 100
TLYELDDPLD AVYGVRFGSL KTQLEDSSGQ LQITGFHLPG EIVGLDGMIE
110 120 130 140 150
SKHVSSAVAL EDSEVCVIRL PEIDRVSTQL PSLQQQFRRL MSREITRSHQ
160 170 180 190 200
MLATVGAMRS EQRLAAFLLN LSQRYAALGY SSTEFVLRMS REEIGNYLGL
210 220 230 240
TLETVSRLFS RFGREGLIRI NQREVRLIDL PGLKQLIGQE SC
Length:242
Mass (Da):27,130
Last modified:September 19, 2003 - v2
Checksum:iCD07103C2AFDAC12
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti27 – 64GMPAN…DAVYG → ACLPTKSRNWTNSSRRPCAW SAAKRSTNSTIPWSRLR in AAC36850 (PubMed:7693656).CuratedAdd BLAST38
Sequence conflicti96D → V in AAC36850 (PubMed:7693656).Curated1
Sequence conflicti174 – 187RYAAL…TEFVL → ATRRSAIRRPNSCV in AAC36850 (PubMed:7693656).CuratedAdd BLAST14
Sequence conflicti223R → A in AAC36850 (PubMed:7693656).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L20602 Unassigned DNA. Translation: AAC36850.1.
BX640414 Genomic DNA. Translation: CAE41493.1.
PIRiA49926.
RefSeqiNP_879971.1. NC_002929.2.
WP_010930241.1. NC_002929.2.

Genome annotation databases

EnsemblBacteriaiCAE41493; CAE41493; BP1197.
GeneIDi2667591.
KEGGibpe:BP1197.
PATRICifig|257313.5.peg.1289.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiBTR_BORPE
AccessioniPrimary (citable) accession number: Q08530
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1994
Last sequence update: September 19, 2003
Last modified: June 7, 2017
This is version 104 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome