Q084R1 (Q084R1_SHEFN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Peptide methionine sulfoxide reductase MsrA 1 HAMAP MF_01401
Short name=Protein-methionine-S-oxide reductase 1 HAMAP MF_01401
EC=1.8.4.11 HAMAP MF_01401

Alternative name(s):
Peptide-methionine (S)-S-oxide reductase 1 HAMAP MF_01401

Gene names

Name:	msrA1 HAMAP MF_01401
Ordered Locus Names:	Sfri_1402

Organism

Shewanella frigidimarina (strain NCIMB 400) [Complete proteome] [HAMAP] EMBL ABI71254.1

Taxonomic identifier

318167 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Alteromonadales › Shewanellaceae › Shewanella

Protein attributes

Sequence length	197 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine By similarity. HAMAP MF_01401
Catalytic activity	L-methionine + thioredoxin disulfide + H2O = L-methionine (S)-S-oxide + thioredoxin. HAMAP MF_01401 Peptide-L-methionine + thioredoxin disulfide + H2O = peptide-L-methionine (S)-S-oxide + thioredoxin. HAMAP MF_01401
Sequence similarities	Belongs to the MsrA Met sulfoxide reductase family. HAMAP MF_01401

Ontologies

Keywords
Domain	Signal EMBL ABI71254.1
Molecular function	Oxidoreductase HAMAP MF_01401 EMBL ABI71254.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	protein modification process Inferred from electronic annotation. Source: HAMAP
Molecular function	peptide-methionine-(S)-S-oxide reductase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 24	24	Potential EMBL ABI71254.1
	Chain	25 – 197	173	Potential EMBL ABI71254.1		PRO_5000130667
Sites
	Active site	32	1	By similarity HAMAP MF_01401

Sequences

	Sequence		Length	Mass (Da)
	Q084R1 [UniParc]. Last modified October 31, 2006. Version 1. Checksum: BD54A11B6074EA6A	FASTA	197	22,240
	10 20 30 40 50 60 MKSTLVLTIF AVSLLSYASN ATADKTILAG GCFWCMESDF EKLDGVTDVI SGFTGGNIKD 70 80 90 100 110 120 PIYNGNHRGH FEAVEITYDP SKVSYAELLE HYWVNIDPFD ASGQFCDKGS SYLSAIFVAN 130 140 150 160 170 180 DTERQIAQQS KSKVEKLFPN SKVVTPILNA STFYPIKGDE SYHQDYYKNN PIRYNAYRWN 190 CGRDKRLNEI WGDKATH

References

[1]

"Complete sequence of Shewanella frigidimarina NCIMB 400." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Fredrickson J.K., Kolker E., McCuel L.A., DiChristina T., Nealson K.H., Newman D., Tiedje J.M. , Zhou J., Romine M.F., Culley D.E., Serres M., Chertkov O., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Richardson P. Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: NCIMB 400.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000447 Genomic DNA. Translation: ABI71254.1.
RefSeq	YP_750092.1. NC_008345.1.
3D structure databases
ProteinModelPortal	Q084R1.
ModBase	Search...
Protein-protein interaction databases
STRING	Q084R1.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4277095.
GenomeReviews	Gene locus Sfri_1402 in contig CP000447_GR.
KEGG	sfr:Sfri_1402.
NMPDR	fig|318167.10.peg.1354.
PATRIC	23496711. VBISheFri14343_1455.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0225.
HOGENOM	HBG748152.
OMA	YEEVCTN.
ProtClustDB	CLSK765127.
Family and domain databases
HAMAP	MF_01401. MsrA. [Tree]
InterPro	IPR002569. Peptide_Met_Sox_Rdtase_MsrA. [Graphical view]
Gene3D	G3DSA:3.30.1060.10. MsrA. 1 hit.
KO	K07304.
Pfam	PF01625. PMSR. 1 hit. [Graphical view]
SUPFAM	SSF55068. MsrA. 1 hit.
TIGRFAMs	TIGR00401. MsrA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q084R1_SHEFN

Accession

Primary (citable) accession number: Q084R1

Entry history

Integrated into UniProtKB/TrEMBL:	October 31, 2006
Last sequence update:	October 31, 2006
Last modified:	December 14, 2011
This is version 43 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)