Reviewed, UniProtKB/Swiss-Prot Q08479 (KAD1_ORYSJ)

Names and origin

Protein names

Recommended name:
    Adenylate kinase A
      Short name=AK A
    EC=2.7.4.3
Alternative name(s):
    ATP-AMP transphosphorylase A

Gene names

Name:	ADK-A
Ordered Locus Names:	Os12g0236400, LOC_Os12g13380

Organism

Oryza sativa subsp. japonica (Rice)

Taxonomic identifier

39947 [NCBI]

Taxonomic lineage

Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › Liliopsida › Poales › Poaceae › BEP clade › Ehrhartoideae › Oryzeae › Oryza

Protein attributes

Sequence length	241 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Function	This small ubiquitous enzyme is essential for maintenance and cell growth.
Catalytic activity	ATP + AMP = 2 ADP.
Sequence similarities	Belongs to the adenylate kinase family.

Ontologies

Keywords
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Gene Ontology (GO)
Biological process	purine nucleotide metabolic process Ref.1 Inferred from expression pattern. Source: Gramene
Molecular function	ATP binding Ref.1 Inferred from expression pattern. Source: Gramene adenylate kinase activity Ref.1 Inferred from expression pattern. Source: Gramene
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 241	241	Adenylate kinase A		PRO_0000158942
Regions
	Nucleotide binding	35 – 43	9	ATP By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q08479-1 [UniParc]. Last modified October 1, 1994. Version 1. Checksum: 7B087909DD2CEE9A	FASTA	241	26,406
	10 20 30 40 50 60 MAANLEDVPS MELMTELLRR MKCSSKPDKR VILVGPPGCG KGTQSPLIKD EFCLCHLATG 70 80 90 100 110 120 DMLRAAVAAK TPLGIKAKEA MDKGELVSDD LVVGIIDEAM KKTSCQKGFI LDGFPRTVVQ 130 140 150 160 170 180 AQKLDEMLAK QGTKIDKVLN FAIDDAILEE RITGRWIHPS SGRSYHTKFA PPKTPGLDDV 190 200 210 220 230 240 TGEPLIQRKD DTAAVLKSRL EAFHVQTKPV IDYYTKKGIV ANLHAEKPPK EVTVEVQKAL S

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Molecular characterization of cDNA encoding for adenylate kinase of rice (Oryza sativa L.)." Kawai M., Kidou S., Kato A., Uchimiya H. Plant J. 2:845-854(1992) [PubMed: 1302636] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA]. Strain: cv. Yamahoushi.
[2]	"The sequence of rice chromosomes 11 and 12, rich in disease resistance genes and recent gene duplications." The rice chromosomes 11 and 12 sequencing consortia BMC Biol. 3:20-20(2005) [PubMed: 16188032] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Nipponbare.
[3]	"Oryza sativa AK-a gene, promoter region and partial ORF." Fukuzawa H., Uchimiya H., Tagawa M., Arai S. Submitted (APR-2000) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-209.

Cross-references

Sequence databases
EMBLGenBankDDBJ	D10334 mRNA. Translation: BAA01180.1. DP000011 Genomic DNA. Translation: ABA96905.1. AB041773 Genomic DNA. Translation: BAA94761.1.
RefSeq	NP_001066462.1.
UniGene	Os.134
3D structure databases
HSSP	HSSP built from PDB template 1AKY based on UniProtKB P07170.
ModBase	Search...
Genome annotation databases
GeneID	4351850.
KEGG	osa:4351850.
Organism-specific databases
Gramene	Q08479.
Family and domain databases
InterPro	IPR006259. Adenyl_kin_sub. IPR000850. Adenylate_kin. IPR007862. Adenylate_kinase_Znf_lid. [Graphical view]
PANTHER	PTHR23359. Adenylate_kin. 1 hit.
Pfam	PF00406. ADK. 1 hit. PF05191. ADK_lid. 1 hit. [Graphical view]
PRINTS	PR00094. ADENYLTKNASE.
ProDom	PD000657. Adenylate_kin. 1 hit. [Graphical view] [Entries sharing at least one domain]
TIGRFAMs	TIGR01351. adk. 1 hit.
PROSITE	PS00113. ADENYLATE_KINASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

KAD1_ORYSJ

Accession

Primary (citable) accession number: Q08479
Secondary accession number(s): Q2QVB5, Q9MAY0

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 1, 1994
Last sequence update:	October 1, 1994
Last modified:	June 16, 2009
This is version 60 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

PPAP (Plant Proteome Annotation Project)