Q08361 (AAD15_YEAST) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Putative aryl-alcohol dehydrogenase AAD15
EC=1.1.1.-

Gene names

Name:	AAD15
Ordered Locus Names:	YOL165C

Organism

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

Taxonomic identifier

559292 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces

Protein attributes

Sequence length	143 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Putative aryl-alcohol dehydrogenase By similarity.
Sequence similarities	Belongs to the aldo/keto reductase 2 family.
Caution	In contrast to other aldo/keto reductase 2 proteins, it lacks the N-terminal half which contains the active site. It is therefore unlikely that it acts as a functional oxydoreductase.

Ontologies

Keywords
Molecular function	Oxidoreductase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Molecular function	oxidoreductase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 143	143	Putative aryl-alcohol dehydrogenase AAD15		PRO_0000070370

Sequences

	Sequence		Length	Mass (Da)
	Q08361 [UniParc]. Last modified November 1, 1996. Version 1. Checksum: B1D8F0399364F354	FASTA	143	15,722
	10 20 30 40 50 60 MARHFGMALA PWDVMGGGRF QSKKAMEERR KNGECIRSFV GASEQTDAEI KISEALAKVA 70 80 90 100 110 120 EEHGTESVTA IAIAYVRSKA KNVFPSVEGG KIEDLKENIK ALSIDLTPDN IKYLENVVPF 130 140 DIGFPNTFIV LNSLTQKYGT NNV

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The nucleotide sequence of Saccharomyces cerevisiae chromosome XV." Dujon B., Albermann K., Aldea M., Alexandraki D., Ansorge W., Arino J., Benes V., Bohn C., Bolotin-Fukuhara M., Bordonne R., Boyer J., Camasses A., Casamayor A., Casas C., Cheret G., Cziepluch C., Daignan-Fornier B., Dang V.-D. , de Haan M., Delius H., Durand P., Fairhead C., Feldmann H., Gaillon L., Galisson F., Gamo F.-J., Gancedo C., Goffeau A., Goulding S.E., Grivell L.A., Habbig B., Hand N.J., Hani J., Hattenhorst U., Hebling U., Hernando Y., Herrero E., Heumann K., Hiesel R., Hilger F., Hofmann B., Hollenberg C.P., Hughes B., Jauniaux J.-C., Kalogeropoulos A., Katsoulou C., Kordes E., Lafuente M.J., Landt O., Louis E.J., Maarse A.C., Madania A., Mannhaupt G., Marck C., Martin R.P., Mewes H.-W., Michaux G., Paces V., Parle-McDermott A.G., Pearson B.M., Perrin A., Pettersson B., Poch O., Pohl T.M., Poirey R., Portetelle D., Pujol A., Purnelle B., Ramezani Rad M., Rechmann S., Schwager C., Schweizer M., Sor F., Sterky F., Tarassov I.A., Teodoru C., Tettelin H., Thierry A., Tobiasch E., Tzermia M., Uhlen M., Unseld M., Valens M., Vandenbol M., Vetter I., Vlcek C., Voet M., Volckaert G., Voss H., Wambutt R., Wedler H., Wiemann S., Winsor B., Wolfe K.H., Zollner A., Zumstein E., Kleine K. Nature 387:98-102(1997) [PubMed: 9169874] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 96604 / S288c / FY1679.
[2]	Saccharomyces Genome Database Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases Cited for: GENOME REANNOTATION. Strain: ATCC 204508 / S288c.
[3]	"Analysis of the seven-member AAD gene set demonstrates that genetic redundancy in yeast may be more apparent than real." Delneri D., Gardner D.C.J., Oliver S.G. Genetics 153:1591-1600(1999) [PubMed: 10581269] [Abstract] Cited for: NOMENCLATURE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	Z74907 Genomic DNA. Translation: CAA99187.1. BK006948 Genomic DNA. Translation: DAA10620.1.
PIR	S66864.
RefSeq	NP_014477.1. NM_001183418.1.
3D structure databases
ProteinModelPortal	Q08361.
ModBase	Search...
Protein-protein interaction databases
IntAct	Q08361. 1 interaction.
STRING	Q08361.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblFungi	YOL165C; YOL165C; YOL165C.
GeneID	853999.
KEGG	sce:YOL165C.
NMPDR	fig|4932.3.peg.5560.
Organism-specific databases
CYGD	YOL165c.
SGD	S000005525. AAD15.
Phylogenomic databases
eggNOG	fuNOG05818.
GeneTree	EFGT00050000001340.
HOGENOM	HBG203571.
OrthoDB	EOG45TGWW.
Gene expression databases
Genevestigator	Q08361.
GermOnline	YOL165C. Saccharomyces cerevisiae.
Family and domain databases
InterPro	IPR001395. Aldo/ket_red. IPR023210. NADP_OxRdtase_dom. [Graphical view]
Gene3D	G3DSA:3.20.20.100. Aldo/ket_red. 1 hit.
PANTHER	PTHR11732. Aldo/ket_red. 1 hit.
Pfam	PF00248. Aldo_ket_red. 1 hit. [Graphical view]
SUPFAM	SSF51430. Aldo/ket_red. 1 hit.
ProtoNet	Search...
Other
NextBio	975494.

Entry information

Entry name

AAD15_YEAST

Accession

Primary (citable) accession number: Q08361
Secondary accession number(s): D6W1Q4

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 25, 2005
Last sequence update:	November 1, 1996
Last modified:	December 14, 2011
This is version 69 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program