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Protein

Alkyl/aryl-sulfatase BDS1

Gene

BDS1

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Alkyl/aryl-sulfatase. Enables the use of SDS and 4-nitrocatechol as sulfur source.1 Publication

Miscellaneous

The presence of this bacterial-like protein in Saccharomyces cerevisiae results probably from a recent horizontal gene transfer event.1 Publication

Cofactori

Zn2+By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi162Zinc; via tele nitrogenBy similarity1
Metal bindingi164Zinc; via pros nitrogenBy similarity1
Metal bindingi166ZincBy similarity1

GO - Molecular functioni

  • alkyl sulfatase activity Source: SGD
  • arylsulfatase activity Source: SGD
  • metal ion binding Source: UniProtKB-KW
  • protein dimerization activity Source: InterPro

GO - Biological processi

  • dodecyl sulfate metabolic process Source: SGD

Keywordsi

Molecular functionHydrolase
LigandMetal-binding, Zinc

Enzyme and pathway databases

BioCyciYEAST:G3O-33551-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Alkyl/aryl-sulfatase BDS11 Publication (EC:3.1.6.-)
Alternative name(s):
Bacterially-derived sulfatase 11 Publication
Gene namesi
Name:BDS1
Ordered Locus Names:YOL164W
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome XV

Organism-specific databases

EuPathDBiFungiDB:YOL164W
SGDiS000005524 BDS1

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002276821 – 646Alkyl/aryl-sulfatase BDS1Add BLAST646

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei1N-acetylmethionineCombined sources1

Keywords - PTMi

Acetylation

Proteomic databases

PaxDbiQ08347
PRIDEiQ08347

PTM databases

iPTMnetiQ08347

Expressioni

Inductioni

Expression is increased in sulfur-limited chemostat cultures.1 Publication

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

BioGridi34254, 14 interactors
IntActiQ08347, 4 interactors
STRINGi4932.YOL164W

Structurei

3D structure databases

ProteinModelPortaliQ08347
SMRiQ08347
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the metallo-beta-lactamase superfamily.Curated

Phylogenomic databases

GeneTreeiENSGT00390000013976
HOGENOMiHOG000050609
InParanoidiQ08347
OMAiYFGSHHW
OrthoDBiEOG092C0XNX

Family and domain databases

Gene3Di1.25.40.880, 1 hit
3.30.1050.10, 1 hit
InterProiView protein in InterPro
IPR038536 Alkyl/aryl-sulf_dimr_sf
IPR029229 Alkyl_sulf_C
IPR029228 Alkyl_sulf_dimr
IPR001279 Metallo-B-lactamas
IPR036866 RibonucZ/Hydroxyglut_hydro
IPR036527 SCP2_sterol-bd_dom_sf
PfamiView protein in Pfam
PF14864 Alkyl_sulf_C, 1 hit
PF14863 Alkyl_sulf_dimr, 1 hit
PF00753 Lactamase_B, 1 hit
SMARTiView protein in SMART
SM00849 Lactamase_B, 1 hit
SUPFAMiSSF55718 SSF55718, 1 hit
SSF56281 SSF56281, 1 hit

Sequencei

Sequence statusi: Complete.

Q08347-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIGAFKRNRG SSQSFAKECQ PSTLKANLEV AKELPFSDRR DFEDATQGYI
60 70 80 90 100
GSLSDEQIIG PDGGVVWCMK SYGFLEPETP ANTVNPSLWR QAQLNAIHGL
110 120 130 140 150
FKITDNVYQV RGLDISNMTI IEGNTSLIII DTLFTTETAQ ESLKLYYRHR
160 170 180 190 200
PQKPVRTVIY THSHSDHYGG VKGIVKEADV KSGEVQIIAP VGFMESVVAE
210 220 230 240 250
NILAGNAMHR RSQYQFGMLL SPSVKGHVDC GIGKAASHGT VTLIAPTIII
260 270 280 290 300
EEPVEERTID GVDFVFQLAP GSEAPSEMLI YMPQQRVLNM AEDVTHHMHN
310 320 330 340 350
LYALRGVEVR DGNQWAKYID AARVAFGSKT DVLIAQHHWP TTGQMRINEL
360 370 380 390 400
LKKQRDMYKF IHDQTLRLLN QGYTSRDIAE TLRMPSSLEQ EWSTRGYYGT
410 420 430 440 450
LSHNVKAVYQ KYLGWYDANP ANLNPLPPVA YAKKAVEYMG GADAVLARAY
460 470 480 490 500
KDFQKGEFRW VASVVNQLVF ADPNNHQARE LCADALEQLG YQAEASTWRN
510 520 530 540 550
AYLVGAMELR QGVPKRRSTG KRNNIAVLNN EMFFDFLAVR LNATKAEGKI
560 570 580 590 600
IVSNWCFINS NERFVITLEN CALTYIQGWQ TDADATITLK RTTFEALLAN
610 620 630 640
EITMVDFLRS KEVEIEGNRL RIEELLKLFD DFDQSFPVVE PMGGST
Length:646
Mass (Da):72,646
Last modified:November 1, 1996 - v1
Checksum:i153BA6F9831F4642
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z74906 Genomic DNA Translation: CAA99186.1
BK006948 Genomic DNA Translation: DAA10622.1
PIRiS66863
RefSeqiNP_014478.1, NM_001183417.1

Genome annotation databases

EnsemblFungiiYOL164W; YOL164W; YOL164W
GeneIDi854000
KEGGisce:YOL164W

Similar proteinsi

Entry informationi

Entry nameiBDS1_YEAST
AccessioniPrimary (citable) accession number: Q08347
Secondary accession number(s): D6W1Q6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 21, 2006
Last sequence update: November 1, 1996
Last modified: March 28, 2018
This is version 124 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health