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Q08347 (BDS1_YEAST) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 95. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Alkyl/aryl-sulfatase BDS1

EC=3.1.6.-
Alternative name(s):
Bacterially-derived sulfatase 1
Gene names
Name:BDS1
Ordered Locus Names:YOL164W
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]
Taxonomic identifier559292 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces

Protein attributes

Sequence length646 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Alkyl/aryl-sulfatase. Enables the use of SDS and 4-nitrocatechol as sulfur source. Ref.4

Induction

Expression is increased in sulfur-limited chemostat cultures. Ref.3

Miscellaneous

The presence of this bacterial-like protein in Saccharomyces cerevisiae results probably from a recent horizontal gene transfer event.

Sequence similarities

Belongs to the metallo-beta-lactamase superfamily.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 646646Alkyl/aryl-sulfatase BDS1
PRO_0000227682

Amino acid modifications

Modified residue11N-acetylmethionine Ref.5

Sequences

Sequence LengthMass (Da)Tools
Q08347 [UniParc].

Last modified November 1, 1996. Version 1.
Checksum: 153BA6F9831F4642

FASTA64672,646
        10         20         30         40         50         60 
MIGAFKRNRG SSQSFAKECQ PSTLKANLEV AKELPFSDRR DFEDATQGYI GSLSDEQIIG 

        70         80         90        100        110        120 
PDGGVVWCMK SYGFLEPETP ANTVNPSLWR QAQLNAIHGL FKITDNVYQV RGLDISNMTI 

       130        140        150        160        170        180 
IEGNTSLIII DTLFTTETAQ ESLKLYYRHR PQKPVRTVIY THSHSDHYGG VKGIVKEADV 

       190        200        210        220        230        240 
KSGEVQIIAP VGFMESVVAE NILAGNAMHR RSQYQFGMLL SPSVKGHVDC GIGKAASHGT 

       250        260        270        280        290        300 
VTLIAPTIII EEPVEERTID GVDFVFQLAP GSEAPSEMLI YMPQQRVLNM AEDVTHHMHN 

       310        320        330        340        350        360 
LYALRGVEVR DGNQWAKYID AARVAFGSKT DVLIAQHHWP TTGQMRINEL LKKQRDMYKF 

       370        380        390        400        410        420 
IHDQTLRLLN QGYTSRDIAE TLRMPSSLEQ EWSTRGYYGT LSHNVKAVYQ KYLGWYDANP 

       430        440        450        460        470        480 
ANLNPLPPVA YAKKAVEYMG GADAVLARAY KDFQKGEFRW VASVVNQLVF ADPNNHQARE 

       490        500        510        520        530        540 
LCADALEQLG YQAEASTWRN AYLVGAMELR QGVPKRRSTG KRNNIAVLNN EMFFDFLAVR 

       550        560        570        580        590        600 
LNATKAEGKI IVSNWCFINS NERFVITLEN CALTYIQGWQ TDADATITLK RTTFEALLAN 

       610        620        630        640 
EITMVDFLRS KEVEIEGNRL RIEELLKLFD DFDQSFPVVE PMGGST 

« Hide

References

« Hide 'large scale' references
[1]"The nucleotide sequence of Saccharomyces cerevisiae chromosome XV."
Dujon B., Albermann K., Aldea M., Alexandraki D., Ansorge W., Arino J., Benes V., Bohn C., Bolotin-Fukuhara M., Bordonne R., Boyer J., Camasses A., Casamayor A., Casas C., Cheret G., Cziepluch C., Daignan-Fornier B., Dang V.-D. expand/collapse author list , de Haan M., Delius H., Durand P., Fairhead C., Feldmann H., Gaillon L., Galisson F., Gamo F.-J., Gancedo C., Goffeau A., Goulding S.E., Grivell L.A., Habbig B., Hand N.J., Hani J., Hattenhorst U., Hebling U., Hernando Y., Herrero E., Heumann K., Hiesel R., Hilger F., Hofmann B., Hollenberg C.P., Hughes B., Jauniaux J.-C., Kalogeropoulos A., Katsoulou C., Kordes E., Lafuente M.J., Landt O., Louis E.J., Maarse A.C., Madania A., Mannhaupt G., Marck C., Martin R.P., Mewes H.-W., Michaux G., Paces V., Parle-McDermott A.G., Pearson B.M., Perrin A., Pettersson B., Poch O., Pohl T.M., Poirey R., Portetelle D., Pujol A., Purnelle B., Ramezani Rad M., Rechmann S., Schwager C., Schweizer M., Sor F., Sterky F., Tarassov I.A., Teodoru C., Tettelin H., Thierry A., Tobiasch E., Tzermia M., Uhlen M., Unseld M., Valens M., Vandenbol M., Vetter I., Vlcek C., Voet M., Volckaert G., Voss H., Wambutt R., Wedler H., Wiemann S., Winsor B., Wolfe K.H., Zollner A., Zumstein E., Kleine K.
Nature 387:98-102(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[2]"The reference genome sequence of Saccharomyces cerevisiae: Then and now."
Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R., Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S., Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.
G3 (Bethesda) 4:389-398(2014) [PubMed] [Europe PMC] [Abstract]
Cited for: GENOME REANNOTATION.
Strain: ATCC 204508 / S288c.
[3]"The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur."
Boer V.M., de Winde J.H., Pronk J.T., Piper M.D.W.
J. Biol. Chem. 278:3265-3274(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: INDUCTION.
[4]"Contribution of horizontal gene transfer to the evolution of Saccharomyces cerevisiae."
Hall C.R., Brachat S., Dietrich F.S.
Eukaryot. Cell 4:1102-1115(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: FUNCTION.
[5]"N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB."
Van Damme P., Lasa M., Polevoda B., Gazquez C., Elosegui-Artola A., Kim D.S., De Juan-Pardo E., Demeyer K., Hole K., Larrea E., Timmerman E., Prieto J., Arnesen T., Sherman F., Gevaert K., Aldabe R.
Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012) [PubMed] [Europe PMC] [Abstract]
Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT MET-1, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
Z74906 Genomic DNA. Translation: CAA99186.1.
BK006948 Genomic DNA. Translation: DAA10622.1.
PIRS66863.
RefSeqNP_014478.1. NM_001183417.1.

3D structure databases

ProteinModelPortalQ08347.
SMRQ08347. Positions 16-640.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid34254. 2 interactions.
STRING4932.YOL164W.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiYOL164W; YOL164W; YOL164W.
GeneID854000.
KEGGsce:YOL164W.

Organism-specific databases

CYGDYOL164w.
SGDS000005524. BDS1.

Phylogenomic databases

eggNOGCOG2015.
GeneTreeENSGT00390000013976.
HOGENOMHOG000050609.
OMATWGNDNV.
OrthoDBEOG7C5MHV.

Enzyme and pathway databases

BioCycYEAST:G3O-33551-MONOMER.

Gene expression databases

GenevestigatorQ08347.

Family and domain databases

Gene3D3.30.1050.10. 1 hit.
3.60.15.10. 2 hits.
InterProIPR029229. Alkyl_sulf_C.
IPR029228. Alkyl_sulf_dimr.
IPR001279. Beta-lactamas-like.
IPR003033. SCP2_sterol-bd_dom.
[Graphical view]
PfamPF14864. Alkyl_sulf_C. 1 hit.
PF14863. Alkyl_sulf_dimr. 1 hit.
PF00753. Lactamase_B. 1 hit.
[Graphical view]
SMARTSM00849. Lactamase_B. 1 hit.
[Graphical view]
SUPFAMSSF55718. SSF55718. 1 hit.
SSF56281. SSF56281. 1 hit.
ProtoNetSearch...

Other

NextBio975497.
PROQ08347.

Entry information

Entry nameBDS1_YEAST
AccessionPrimary (citable) accession number: Q08347
Secondary accession number(s): D6W1Q6
Entry history
Integrated into UniProtKB/Swiss-Prot: March 21, 2006
Last sequence update: November 1, 1996
Last modified: June 11, 2014
This is version 95 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Yeast chromosome XV

Yeast (Saccharomyces cerevisiae) chromosome XV: entries and gene names

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD

SIMILARITY comments

Index of protein domains and families