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Protein

Polyphenol oxidase D, chloroplastic

Gene
N/A
Organism
Solanum lycopersicum (Tomato) (Lycopersicon esculentum)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the oxidation of mono- and o-diphenols to o-diquinones.

Catalytic activityi

2 catechol + O2 = 2 1,2-benzoquinone + 2 H2O.

Cofactori

Cu2+By similarityNote: Binds 2 copper ions per subunit.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi176Copper ABy similarity1
Metal bindingi194Copper ABy similarity1
Metal bindingi203Copper ABy similarity1
Metal bindingi324Copper BBy similarity1
Metal bindingi328Copper BBy similarity1
Metal bindingi366Copper BBy similarity1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductase
LigandCopper, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Polyphenol oxidase D, chloroplastic (EC:1.10.3.1)
Short name:
PPO
Alternative name(s):
Catechol oxidase
OrganismiSolanum lycopersicum (Tomato) (Lycopersicon esculentum)
Taxonomic identifieri4081 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaeasteridslamiidsSolanalesSolanaceaeSolanoideaeSolaneaeSolanumLycopersicon
Proteomesi

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Chloroplast, Plastid, Thylakoid

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transit peptidei1 – 83ChloroplastBy similarityAdd BLAST83
ChainiPRO_000003591384 – 591Polyphenol oxidase D, chloroplasticAdd BLAST508

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi94 ↔ 110By similarity
Disulfide bondi109 ↔ 177By similarity
Cross-linki180 ↔ 1942'-(S-cysteinyl)-histidine (Cys-His)By similarity

Keywords - PTMi

Disulfide bond, Thioether bond

Proteomic databases

PRIDEiQ08306

Expressioni

Gene expression databases

ExpressionAtlasiQ08306 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliQ08306
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the tyrosinase family.Curated

Keywords - Domaini

Transit peptide

Phylogenomic databases

eggNOGiENOG410II6J Eukaryota
ENOG410XS94 LUCA

Family and domain databases

Gene3Di1.10.1280.10, 1 hit
InterProiView protein in InterPro
IPR016213 Polyphenol_oxidase
IPR022740 Polyphenol_oxidase_C
IPR022739 Polyphenol_oxidase_cen
IPR002227 Tyrosinase_Cu-bd
IPR008922 Unchr_di-copper_centre
PfamiView protein in Pfam
PF12142 PPO1_DWL, 1 hit
PF12143 PPO1_KFDV, 1 hit
PF00264 Tyrosinase, 1 hit
PIRSFiPIRSF000290 PPO_plant, 1 hit
PRINTSiPR00092 TYROSINASE
SUPFAMiSSF48056 SSF48056, 1 hit
PROSITEiView protein in PROSITE
PS00497 TYROSINASE_1, 1 hit
PS00498 TYROSINASE_2, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q08306-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASLCSNSST TSLKTPFTSL GSTPKPCQLF LHGKRNKAFK VSCKVTNTNG
60 70 80 90 100
NQDETNSVDR RNVLLGLGGL YGVANAIPLA ASAAPTPPPD LSSCSIARID
110 120 130 140 150
ENQVVSYSCC APKPDDMEKV PYYKFPSMTK LRVRQPAHEA DEEYIAKYNV
160 170 180 190 200
SVTKMRDLDK TQPLNPIGFK QQANIHCAYC NGAYRIGGKE LQVHNSWLFF
210 220 230 240 250
PFHRWYLYFY ESNAGKLIDD PTFALPYWNW DHPKGMRFPA MYDREGTFLF
260 270 280 290 300
DETRDQSHRN GTVIDLGFFG NEVETTQLQM MSNNLTLMYR QMVTNAPCPR
310 320 330 340 350
MFFGDLMISG ITLNSPGTIE NIPHGPVHIW SGTVRGSTLP NGAISKRGEY
360 370 380 390 400
GHFYSAGLDP VFFCHHSNVD RMWSEWKATG GKRTDITHKD WLNSEFFFYD
410 420 430 440 450
ENENPYRVKV RDCLDTKKMG YDYKPMRTPW RNFKPLTKAS AGKVNTSSIP
460 470 480 490 500
PVSQAFPLAK LDKAVSFSIN RPTSSRTPQE KNAQEEMLTF NSIRYDNRGY
510 520 530 540 550
IRFDVFLNVD NNVNANELDK AEFAGSYTSL PHVHRAGETN HIATVDFQLA
560 570 580 590
ITELLEDIGL EDEDTIAVTL VPKRGGEGIS IENATISLAD C
Length:591
Mass (Da):66,529
Last modified:February 1, 1996 - v2
Checksum:i083C08429E80C85F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z12836 Genomic DNA Translation: CAA78298.1
PIRiS33542

Entry informationi

Entry nameiPPOD_SOLLC
AccessioniPrimary (citable) accession number: Q08306
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: February 1, 1996
Last modified: May 23, 2018
This is version 85 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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