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Protein

Bypass of stop codon protein 6

Gene

BSC6

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Probable transporter.

Miscellaneous

Present with 414 molecules/cell in log phase SD medium.1 Publication

GO - Biological processi

Keywordsi

Biological processTransport

Enzyme and pathway databases

BioCyciYEAST:G3O-33530-MONOMER

Protein family/group databases

TCDBi2.A.1.7.13 the major facilitator superfamily (mfs)

Names & Taxonomyi

Protein namesi
Recommended name:
Bypass of stop codon protein 6
Gene namesi
Name:BSC6
Ordered Locus Names:YOL137W
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome XV

Organism-specific databases

EuPathDBiFungiDB:YOL137W
SGDiS000005497 BSC6

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 72LumenalSequence analysisAdd BLAST72
Transmembranei73 – 93HelicalSequence analysisAdd BLAST21
Topological domaini94 – 144CytoplasmicSequence analysisAdd BLAST51
Transmembranei145 – 165HelicalSequence analysisAdd BLAST21
Topological domaini166 – 167LumenalSequence analysis2
Transmembranei168 – 188HelicalSequence analysisAdd BLAST21
Topological domaini189 – 205CytoplasmicSequence analysisAdd BLAST17
Transmembranei206 – 226HelicalSequence analysisAdd BLAST21
Topological domaini227 – 232LumenalSequence analysis6
Transmembranei233 – 253HelicalSequence analysisAdd BLAST21
Topological domaini254 – 300CytoplasmicSequence analysisAdd BLAST47
Transmembranei301 – 321HelicalSequence analysisAdd BLAST21
Topological domaini322 – 340LumenalSequence analysisAdd BLAST19
Transmembranei341 – 361HelicalSequence analysisAdd BLAST21
Topological domaini362 – 373CytoplasmicSequence analysisAdd BLAST12
Transmembranei374 – 394HelicalSequence analysisAdd BLAST21
Topological domaini395 – 397LumenalSequence analysis3
Transmembranei398 – 418HelicalSequence analysisAdd BLAST21
Topological domaini419 – 439CytoplasmicSequence analysisAdd BLAST21
Transmembranei440 – 460HelicalSequence analysisAdd BLAST21
Topological domaini461 – 462LumenalSequence analysis2
Transmembranei463 – 483HelicalSequence analysisAdd BLAST21
Topological domaini484 – 497CytoplasmicSequence analysisAdd BLAST14

Keywords - Cellular componenti

Golgi apparatus, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000848641 – 497Bypass of stop codon protein 6Add BLAST497

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei37PhosphoserineCombined sources1
Modified residuei41PhosphoserineCombined sources1
Glycosylationi49N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein, Phosphoprotein

Proteomic databases

MaxQBiQ08280
PaxDbiQ08280
PRIDEiQ08280

PTM databases

iPTMnetiQ08280

Interactioni

Protein-protein interaction databases

BioGridi34239, 73 interactors
DIPiDIP-4683N
IntActiQ08280, 7 interactors
MINTiQ08280
STRINGi4932.YOL137W

Structurei

3D structure databases

ProteinModelPortaliQ08280
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the major facilitator superfamily.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

HOGENOMiHOG000095266
InParanoidiQ08280
OMAiRFGFVLM
OrthoDBiEOG092C3Y59

Family and domain databases

CDDicd06174 MFS, 1 hit
InterProiView protein in InterPro
IPR011701 MFS
IPR020846 MFS_dom
IPR036259 MFS_trans_sf
PfamiView protein in Pfam
PF07690 MFS_1, 1 hit
SUPFAMiSSF103473 SSF103473, 1 hit
PROSITEiView protein in PROSITE
PS50850 MFS, 1 hit

Sequencei

Sequence statusi: Complete.

Q08280-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDASSVPPKV DDYGMYTTEI SHHNPIELKN LLSSSDSRRN SQDEDSLPNN
60 70 80 90 100
TNLIKEIDWQ GEKVKTYPLN YQTVPLVKLQ VIACLIMFVV FGMNDQTVGA
110 120 130 140 150
LLPTLIEYYH ISRVDVSNVF IVQLCGYVMA SLSKERLNKH FGMRGGMLLA
160 170 180 190 200
AGLCIVFLII LATAPSSFYV CMFCGLPLGL GIGILDSTGN VLMGSLLVHK
210 220 230 240 250
NELMGIMHGL YGAAAMVTPP LVSYFVEWGH WSLFFLIPLF FSIIGMIVIF
260 270 280 290 300
PAFKFETASK YDYLCSVENK ESNNDVEEAG DNSLMESTKA SPGFFELLRN
310 320 330 340 350
PAIFLYSLYL FLYLGAEITT GSWFFSYLLE TKSSNKVAMS YIAASFWTGL
360 370 380 390 400
TVGRLCLGFV TERFFENEYK ASKAYAFLTL SSYTLFVLVG LINSSSVFYF
410 420 430 440 450
VVLFFVVFCC GTFIGPLFPN ASIVALQVLP KRLHVSGVGV AVAVGGCGGA
460 470 480 490
AIPYLAGVIA HTVGIQYIPL LCWIMVALFT LEWTLYPKFI KGHEEYF
Length:497
Mass (Da):55,084
Last modified:November 1, 1996 - v1
Checksum:i2458A5A8DA6BC731
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti472C → R in AAT92920 (PubMed:17322287).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X95465 Genomic DNA Translation: CAA64736.1
Z74879 Genomic DNA Translation: CAA99158.1
AY692901 Genomic DNA Translation: AAT92920.1
BK006948 Genomic DNA Translation: DAA10648.1
PIRiS66834
RefSeqiNP_014504.1, NM_001183391.1

Genome annotation databases

EnsemblFungiiYOL137W; YOL137W; YOL137W
GeneIDi853983
KEGGisce:YOL137W

Similar proteinsi

Entry informationi

Entry nameiBSC6_YEAST
AccessioniPrimary (citable) accession number: Q08280
Secondary accession number(s): D6W1T2, Q6B229
Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 16, 2005
Last sequence update: November 1, 1996
Last modified: May 23, 2018
This is version 135 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome XV
    Yeast (Saccharomyces cerevisiae) chromosome XV: entries and gene names

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