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Protein

Magnesium transporter ALR1

Gene

ALR1

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Plasma membrane magnesium transporter.1 Publication

GO - Molecular functioni

  • inorganic cation transmembrane transporter activity Source: SGD
  • magnesium ion transmembrane transporter activity Source: GO_Central

GO - Biological processi

  • cation transport Source: SGD
  • magnesium ion transport Source: SGD
Complete GO annotation...

Keywords - Biological processi

Transport

Keywords - Ligandi

Magnesium

Enzyme and pathway databases

BioCyciYEAST:G3O-33525-MONOMER.
BRENDAi3.6.3.2. 984.

Protein family/group databases

TCDBi1.A.35.2.1. the cora metal ion transporter (mit) family.

Names & Taxonomyi

Protein namesi
Recommended name:
Magnesium transporter ALR1
Alternative name(s):
Aluminum resistance protein 1
Gene namesi
Name:ALR1
Ordered Locus Names:YOL130W
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome XV

Organism-specific databases

EuPathDBiFungiDB:YOL130W.
SGDiS000005490. ALR1.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei744 – 764HelicalSequence analysisAdd BLAST21
Transmembranei773 – 793HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

  • integral component of membrane Source: UniProtKB-KW
  • plasma membrane Source: SGD
Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedCombined sources
ChainiPRO_00002015352 – 859Magnesium transporter ALR1Add BLAST858

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei2N-acetylserineCombined sources1
Modified residuei77PhosphotyrosineCombined sources1
Modified residuei85PhosphoserineCombined sources1
Modified residuei185PhosphoserineCombined sources1
Modified residuei188PhosphoserineCombined sources1
Modified residuei220PhosphoserineCombined sources1
Modified residuei221PhosphoserineCombined sources1
Modified residuei236PhosphoserineCombined sources1
Modified residuei242PhosphothreonineCombined sources1
Modified residuei850PhosphoserineCombined sources1

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

MaxQBiQ08269.
PRIDEiQ08269.

PTM databases

iPTMnetiQ08269.

Interactioni

Protein-protein interaction databases

BioGridi34245. 39 interactors.
DIPiDIP-1184N.
IntActiQ08269. 12 interactors.
MINTiMINT-387492.

Structurei

3D structure databases

ProteinModelPortaliQ08269.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

GeneTreeiENSGT00390000009621.
HOGENOMiHOG000171963.
InParanoidiQ08269.
KOiK16073.
OMAiCQDEANG.
OrthoDBiEOG092C0RNR.

Family and domain databases

InterProiIPR002523. MgTranspt_CorA/ZnTranspt_ZntB.
[Graphical view]
PfamiPF01544. CorA. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q08269-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSSSSSSES SPNLSRSNSL ANTMVSMKTE DHTGLYDHRQ HPDSLPVRHQ
60 70 80 90 100
PPTLKNKEIA KSTKPSIPKE QKSATRYNSH VDVGSVPSRG RMDFEDEGQG
110 120 130 140 150
MDETVAHHQL RASAILTSNA RPSRLAHSMP HQRQLYVESN IHTPPKDVGV
160 170 180 190 200
KRDYTMSSST ASSGNKSKLS ASSSASPITK VRKSSLVSPV LEIPHESKSD
210 220 230 240 250
THSKLAKPKK RTYSTTSAHS SINPAVLLTK STSQKSDADD DTLERKPVRM
260 270 280 290 300
NTRASFDSDV SQASRDSQET EEDVCFPMPP QLHTRVNGID FDELEEYAQF
310 320 330 340 350
ANAEKSQFLA SLQVPNEQKY SNVSQDIGFT SSTSTSGSSA ALKYTPRVSQ
360 370 380 390 400
TGEKSESTNE TEIHEKKEDE HEKIKPSLHP GISFGKNKVE GEENENIPSN
410 420 430 440 450
DPAYCSYQGT DFQIPNRFSF FCSESDETVH ASDIPSLVSE GQTFYELFRG
460 470 480 490 500
GEPTWWLDCS CPTDDEMRCI AKAFGIHPLT AEDIRMQETR EKVELFKSYY
510 520 530 540 550
FVCFHTFEND KESEDFLEPI NVYIVVCRSG VLTFHFGPIS HCANVRRRVR
560 570 580 590 600
QLRDYVNVNS DWLCYALIDD ITDSFAPVIQ SIEYEADAIE DSVFMARDMD
610 620 630 640 650
FAAMLQRIGE SRRKTMTLMR LLSGKADVIK MFAKRCQDEA NGIGPALTSQ
660 670 680 690 700
INIANLQARQ DNASHIKNNS STTVPNNYAP TTSQPRGDIA LYLGDIQDHL
710 720 730 740 750
LTMFQNLLAY EKIFSRSHTN YLAQLQVESF NSNNKVTEML GKVTMIGTML
760 770 780 790 800
VPLNVITGLF GMNVKVPGEN SSIAWWFGIL GVLLLLAVLG WFLASYWIKR
810 820 830 840 850
IDPPATLNEA AESGAKSVIS SFLPKRNKRF NDRSKNINVR AGPSNKSVAS

LPSRYSRYD
Length:859
Mass (Da):95,869
Last modified:November 1, 1996 - v1
Checksum:i6DA44CA70EFA2693
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti13N → Y in AAC49462 (PubMed:8896265).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U41293 Genomic DNA. Translation: AAC49462.1.
Z74872 Genomic DNA. Translation: CAA99150.1.
Z74871 Genomic DNA. Translation: CAA99149.1.
AY692762 Genomic DNA. Translation: AAT92781.1.
BK006948 Genomic DNA. Translation: DAA10654.1.
PIRiS66827.
RefSeqiNP_014511.1. NM_001183384.1.

Genome annotation databases

EnsemblFungiiYOL130W; YOL130W; YOL130W.
GeneIDi853990.
KEGGisce:YOL130W.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U41293 Genomic DNA. Translation: AAC49462.1.
Z74872 Genomic DNA. Translation: CAA99150.1.
Z74871 Genomic DNA. Translation: CAA99149.1.
AY692762 Genomic DNA. Translation: AAT92781.1.
BK006948 Genomic DNA. Translation: DAA10654.1.
PIRiS66827.
RefSeqiNP_014511.1. NM_001183384.1.

3D structure databases

ProteinModelPortaliQ08269.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi34245. 39 interactors.
DIPiDIP-1184N.
IntActiQ08269. 12 interactors.
MINTiMINT-387492.

Protein family/group databases

TCDBi1.A.35.2.1. the cora metal ion transporter (mit) family.

PTM databases

iPTMnetiQ08269.

Proteomic databases

MaxQBiQ08269.
PRIDEiQ08269.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYOL130W; YOL130W; YOL130W.
GeneIDi853990.
KEGGisce:YOL130W.

Organism-specific databases

EuPathDBiFungiDB:YOL130W.
SGDiS000005490. ALR1.

Phylogenomic databases

GeneTreeiENSGT00390000009621.
HOGENOMiHOG000171963.
InParanoidiQ08269.
KOiK16073.
OMAiCQDEANG.
OrthoDBiEOG092C0RNR.

Enzyme and pathway databases

BioCyciYEAST:G3O-33525-MONOMER.
BRENDAi3.6.3.2. 984.

Miscellaneous databases

PROiQ08269.

Family and domain databases

InterProiIPR002523. MgTranspt_CorA/ZnTranspt_ZntB.
[Graphical view]
PfamiPF01544. CorA. 2 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiALR1_YEAST
AccessioniPrimary (citable) accession number: Q08269
Secondary accession number(s): D6W1T8, Q02811
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1996
Last modified: November 2, 2016
This is version 141 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome XV
    Yeast (Saccharomyces cerevisiae) chromosome XV: entries and gene names

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.