Unreviewed, UniProtKB/TrEMBL Q08166 (Q08166_THEFU)

Names and origin

Protein names

Submitted name:
    Beta-1,4-endoglucanase EMBL AAC06387.1

Gene names

Name:

E1 EMBL AAC06387.1

Organism

Thermomonospora fusca EMBL AAC06387.1

Taxonomic identifier

2021 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Streptosporangineae › Nocardiopsaceae › Thermobifida

Protein attributes

Sequence length	974 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology.

General annotation (Comments)

Sequence similarities

Contains 1 fibronectin type-III domain. RuleBase RU000718V1

Ontologies

Keywords
Domain	Signal
Gene Ontology (GO)
Biological process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	cellulase activity Inferred from electronic annotation. Source: InterPro polysaccharide binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 32	32	Potential EMBL AAC06387.1
	Chain	33 – 974	942	beta-1,4-endoglucanase EMBL AAC06387.1		PRO_5000142289

Sequences

	Sequence		Length	Mass (Da)
	Q08166-1 [UniParc]. Last modified November 1, 1996. Version 1. Checksum: 17FEE7330404A83C	FASTA	974	104,578
	10 20 30 40 50 60 MLRRPRSRSP LVALTAATCR VALGGTAVPA QADEVNQIRN GDFSSGTAPW WGTENIQLNV 70 80 90 100 110 120 TDGMLCVDVP GGTVNPWDVI IGQDDIPLIE GESYAFSFTA SSTVPVSIRA LVQEPVEPWT 130 140 150 160 170 180 TQMDERALLG PEAETYEFVF TSNVDWDDAQ VAFQIGGSDE PWTFCLDDVA LLGRAEPPVY 190 200 210 220 230 240 EPDTGPRVRV NQVGYLPHGP KKATVVTDAT SALTWELADA DGNVVASGQT KPHGADSSSG 250 260 270 280 290 300 LNVHTVDFSS YTTKGSDYTL TVDGETSYPF DIDESVYEEL RVDALSFYYP QRSGIEILDS 310 320 330 340 350 360 IAPGYGRPAG HIGVPPNQGD TDVPCAPGTC DYSLDVSGGW YDAGDHGKYV VNGGISVHQI 370 380 390 400 410 420 MSIYERSQLA DTAQPDKLAD STLRLPETGN GVPDVLDEAR WEMEFLLKMQ VPEGEPLAGM 430 440 450 460 470 480 AHHKIHDEQW TGLPLLPSAD PQPRYLQPPS TAATLNLAAT AAQCARVFEP FDEDFAAECL 490 500 510 520 530 540 AAAETAWDAA KANPNIYAPA FGEGGGPYND NNVTDEFYWA AAELFLTTGK EEYRDAVTSS 550 560 570 580 590 600 PLHTDDEEVF RDGAFDWGWT AALARLQLAT IPNDLADRDR VRQSVVDAAD MYLANVETSP 610 620 630 640 650 660 WGLAYKPNNG VFVWGSNSAV LNNMVILAVA FDLTGDTKYR DGVLEGMDYI FGRNALNQSY 670 680 690 700 710 720 VTGYGDKDSR NQHSRWYAHQ LDPRLPNPPK GTLAGGPNSD STTWDPVAQS KLTGCAPQMC 730 740 750 760 770 780 YIDHIESWST NELTINWNAP LSWIASFIAD QDDAGEPGGE EPGPGDDETP PSKPGNLKAS 790 800 810 820 830 840 DITATSATLT WDASTDNVGV VGYKVSLVRD GDAEEVGTTA QTSYTLTGLS ADQEYTVQVV 850 860 870 880 890 900 AYDAAGNLST PATVTFTTEK EDETPTPSAS CAVTYQTNDW PGGFTASVTL TNTGSTPWDS 910 920 930 940 950 960 WELRFTFPSG QTVSHGWSAN WQQSGSDVTA TSLPWNGSVP PGGGSVNIGF NGTWGGSNTK 970 PEKFTVNGAV CSIG

References

[1]	"DNA sequences of three beta-1,4-endoglucanase genes from Thermomonospora fusca." Lao G., Ghangas G.S., Jung E.D., Wilson D.B. J. Bacteriol. 173:3397-3407(1991) [PubMed: 1904434] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: YX EMBL AAC06387.1.
[2]	"Identification of a celE binding protein and its potential role in induction of the celE gene in Thermomonospora fusca." Lin E., Wilson D.B. J. Bacteriol. 1701:3843-3846(1988) Cited for: NUCLEOTIDE SEQUENCE. Strain: YX EMBL AAC06387.1.
[3]	"Activity studies of eight purified cellulases: specificty, synergism, and binding domain effects." Irwin D.C., Spezio M., Walker L.P., Wilson D.B. Biotechnol. Bioeng. 42:1002-1013(1993) [PubMed: 18613149] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: YX EMBL AAC06387.1.
[4]	"DNA sequences and expression in Streptomyces lividans of an exoglucanase gene and an endoglucanase gene from Thermomonospora fusca." Jung E.D., Lao G., Irwin D., Barr B.K., Benjamin A., Wilson D.B. Appl. Environ. Microbiol. 59:3032-3043(1993) [PubMed: 8215374] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: YX EMBL AAC06387.1.

Cross-references

Sequence databases
EMBLGenBankDDBJ	L20094 Genomic DNA. Translation: AAC06387.1.
3D structure databases
HSSP	HSSP built from PDB template 1K85 based on UniProtKB P20533.
ModBase	Search...
Protein family/group databases
CAZy	CBM2. Carbohydrate-Binding Module Family 2. CBM4. Carbohydrate-Binding Module Family 4. GH9. Glycoside Hydrolase Family 9.
Family and domain databases
InterPro	IPR012341. 6hp_glycosidase. IPR001919. CBD_bac. IPR012291. CBD_carb_bd. IPR003305. CenC_carb_bd. IPR008957. Fibronectin_typ-III-like_fold. IPR003961. FN_III. IPR001701. Glyco_hydro_9. IPR018221. Glyco_hydro_9_AS. IPR004197. Glyco_hydro_9_Ig-like. IPR013783. Ig-like_fold. [Graphical view]
Gene3D	G3DSA:2.60.40.290. CBD_carb_bd. 1 hit. G3DSA:1.50.10.10. CelA/Cel48F_cat. 1 hit. G3DSA:2.60.40.30. FN_III-like. 1 hit. G3DSA:2.60.40.10. Ig-like_fold. 1 hit.
PANTHER	PTHR22298:SF3. Glyco_hydro_9. 1 hit.
Pfam	PF00553. CBM_2. 1 hit. PF02018. CBM_4_9. 1 hit. PF02927. CelD_N. 1 hit. PF00041. fn3. 1 hit. PF00759. Glyco_hydro_9. 1 hit. [Graphical view]
SMART	SM00637. CBD_II. 1 hit. SM00060. FN3. 1 hit. [Graphical view]
PROSITE	PS51173. CBM2. 1 hit. PS50853. FN3. 1 hit. PS00698. GLYCOSYL_HYDROL_F9_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q08166_THEFU

Accession

Primary (citable) accession number: Q08166

Entry history

Integrated into UniProtKB/TrEMBL:	November 1, 1996
Last sequence update:	November 1, 1996
Last modified:	April 14, 2009
This is version 61 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)