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Protein

Endoglucanase

Gene

E1

Organism
Thermobifida fusca (Thermomonospora fusca)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

Endohydrolysis of (1->4)-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosidaseUniRule annotation, Hydrolase
Biological processCarbohydrate metabolism, Cellulose degradationUniRule annotation, Polysaccharide degradation

Protein family/group databases

CAZyiCBM2 Carbohydrate-Binding Module Family 2
CBM4 Carbohydrate-Binding Module Family 4
GH9 Glycoside Hydrolase Family 9

Names & Taxonomyi

Protein namesi
Recommended name:
EndoglucanaseUniRule annotation (EC:3.2.1.4UniRule annotation)
Gene namesi
Name:E1Imported
OrganismiThermobifida fusca (Thermomonospora fusca)Imported
Taxonomic identifieri2021 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaStreptosporangialesNocardiopsaceaeThermobifida

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 32UniRule annotationAdd BLAST32
ChainiPRO_500514237133 – 974EndoglucanaseUniRule annotationAdd BLAST942

Structurei

3D structure databases

ProteinModelPortaliQ08166
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini773 – 862Fibronectin type-IIIInterPro annotationAdd BLAST90
Domaini864 – 974CBM2InterPro annotationAdd BLAST111

Sequence similaritiesi

Belongs to the glycosyl hydrolase 9 (cellulase E) family.UniRule annotation

Keywords - Domaini

SignalUniRule annotation

Phylogenomic databases

eggNOGiENOG4105E08 Bacteria
ENOG410XNTA LUCA

Family and domain databases

CDDicd02850 E_set_Cellulase_N, 1 hit
cd00063 FN3, 1 hit
Gene3Di1.50.10.10, 1 hit
2.60.120.260, 1 hit
2.60.40.10, 2 hits
2.60.40.290, 1 hit
InterProiView protein in InterPro
IPR008928 6-hairpin_glycosidase_sf
IPR012341 6hp_glycosidase-like_sf
IPR001919 CBD2
IPR008965 CBM2/CBM3_carb-bd_dom_sf
IPR012291 CBM2_carb-bd_dom_sf
IPR004197 Cellulase_Ig-like
IPR003305 CenC_carb-bd
IPR003961 FN3_dom
IPR036116 FN3_sf
IPR008979 Galactose-bd-like_sf
IPR001701 Glyco_hydro_9
IPR033126 Glyco_hydro_9_Asp/Glu_AS
IPR013783 Ig-like_fold
IPR014756 Ig_E-set
PfamiView protein in Pfam
PF00553 CBM_2, 1 hit
PF02018 CBM_4_9, 1 hit
PF02927 CelD_N, 1 hit
PF00041 fn3, 1 hit
PF00759 Glyco_hydro_9, 1 hit
SMARTiView protein in SMART
SM00637 CBD_II, 1 hit
SM00060 FN3, 1 hit
SUPFAMiSSF48208 SSF48208, 1 hit
SSF49265 SSF49265, 1 hit
SSF49384 SSF49384, 1 hit
SSF49785 SSF49785, 1 hit
SSF81296 SSF81296, 1 hit
PROSITEiView protein in PROSITE
PS51173 CBM2, 1 hit
PS50853 FN3, 1 hit
PS00698 GLYCOSYL_HYDROL_F9_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q08166-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLRRPRSRSP LVALTAATCR VALGGTAVPA QADEVNQIRN GDFSSGTAPW
60 70 80 90 100
WGTENIQLNV TDGMLCVDVP GGTVNPWDVI IGQDDIPLIE GESYAFSFTA
110 120 130 140 150
SSTVPVSIRA LVQEPVEPWT TQMDERALLG PEAETYEFVF TSNVDWDDAQ
160 170 180 190 200
VAFQIGGSDE PWTFCLDDVA LLGRAEPPVY EPDTGPRVRV NQVGYLPHGP
210 220 230 240 250
KKATVVTDAT SALTWELADA DGNVVASGQT KPHGADSSSG LNVHTVDFSS
260 270 280 290 300
YTTKGSDYTL TVDGETSYPF DIDESVYEEL RVDALSFYYP QRSGIEILDS
310 320 330 340 350
IAPGYGRPAG HIGVPPNQGD TDVPCAPGTC DYSLDVSGGW YDAGDHGKYV
360 370 380 390 400
VNGGISVHQI MSIYERSQLA DTAQPDKLAD STLRLPETGN GVPDVLDEAR
410 420 430 440 450
WEMEFLLKMQ VPEGEPLAGM AHHKIHDEQW TGLPLLPSAD PQPRYLQPPS
460 470 480 490 500
TAATLNLAAT AAQCARVFEP FDEDFAAECL AAAETAWDAA KANPNIYAPA
510 520 530 540 550
FGEGGGPYND NNVTDEFYWA AAELFLTTGK EEYRDAVTSS PLHTDDEEVF
560 570 580 590 600
RDGAFDWGWT AALARLQLAT IPNDLADRDR VRQSVVDAAD MYLANVETSP
610 620 630 640 650
WGLAYKPNNG VFVWGSNSAV LNNMVILAVA FDLTGDTKYR DGVLEGMDYI
660 670 680 690 700
FGRNALNQSY VTGYGDKDSR NQHSRWYAHQ LDPRLPNPPK GTLAGGPNSD
710 720 730 740 750
STTWDPVAQS KLTGCAPQMC YIDHIESWST NELTINWNAP LSWIASFIAD
760 770 780 790 800
QDDAGEPGGE EPGPGDDETP PSKPGNLKAS DITATSATLT WDASTDNVGV
810 820 830 840 850
VGYKVSLVRD GDAEEVGTTA QTSYTLTGLS ADQEYTVQVV AYDAAGNLST
860 870 880 890 900
PATVTFTTEK EDETPTPSAS CAVTYQTNDW PGGFTASVTL TNTGSTPWDS
910 920 930 940 950
WELRFTFPSG QTVSHGWSAN WQQSGSDVTA TSLPWNGSVP PGGGSVNIGF
960 970
NGTWGGSNTK PEKFTVNGAV CSIG
Length:974
Mass (Da):104,578
Last modified:November 1, 1996 - v1
Checksum:i17FEE7330404A83C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L20094 Genomic DNA Translation: AAC06387.1

Similar proteinsi

Entry informationi

Entry nameiQ08166_THEFU
AccessioniPrimary (citable) accession number: Q08166
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: June 20, 2018
This is version 107 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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