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Protein

Protein FMP25, mitochondrial

Gene

FMP25

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

GO - Biological processi

  • mitochondrial respiratory chain complex III assembly Source: SGD
Complete GO annotation...

Enzyme and pathway databases

BioCyciYEAST:G3O-32228-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Protein FMP25, mitochondrial
Alternative name(s):
Found in mitochondrial proteome protein 25
Gene namesi
Name:FMP25
Ordered Locus Names:YLR077W
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome XII

Organism-specific databases

EuPathDBiFungiDB:YLR077W.
SGDiS000004067. FMP25.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei83 – 10523HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

  • integral component of mitochondrial inner membrane Source: SGD
Complete GO annotation...

Keywords - Cellular componenti

Membrane, Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transit peptidei1 – 2525MitochondrionSequence analysisAdd
BLAST
Chaini26 – 583558Protein FMP25, mitochondrialPRO_0000247338Add
BLAST

Proteomic databases

MaxQBiQ08023.

Interactioni

Protein-protein interaction databases

BioGridi31350. 12 interactions.
DIPiDIP-4474N.
IntActiQ08023. 2 interactions.
MINTiMINT-504101.

Structurei

3D structure databases

ProteinModelPortaliQ08023.
SMRiQ08023. Positions 295-546.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Repeati332 – 38958RCC1 1Add
BLAST
Repeati390 – 45263RCC1 2Add
BLAST
Repeati459 – 51052RCC1 3Add
BLAST
Repeati512 – 56958RCC1 4Add
BLAST

Sequence similaritiesi

Contains 4 RCC1 repeats.Curated

Keywords - Domaini

Repeat, Transit peptide, Transmembrane, Transmembrane helix

Phylogenomic databases

HOGENOMiHOG000111193.
InParanoidiQ08023.
OMAiSPEYKEQ.
OrthoDBiEOG092C12QD.

Family and domain databases

Gene3Di2.130.10.30. 2 hits.
InterProiIPR009091. RCC1/BLIP-II.
IPR000408. Reg_chr_condens.
[Graphical view]
PfamiPF00415. RCC1. 1 hit.
[Graphical view]
SUPFAMiSSF50985. SSF50985. 2 hits.
PROSITEiPS00626. RCC1_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q08023-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSFRLFTRTS QRLPRLNWVS PIRRYAKQPQ YDEAELFAEN INHGAYKAKK
60 70 80 90 100
RPSDEHFQWP EKSPDQITKE SELQWERMAK LSAVGQGILI LVVVGGLGTA
110 120 130 140 150
YLRWPELKSW WLIKMNGGRI NATQEQSGQD SLEKLIRQKA KNLLREIPQV
160 170 180 190 200
PAFQLGIDHP GVYIWGRCHS KDSLFPVRVP NLDGRKFRDI LLAPSDDFNT
210 220 230 240 250
NFAIDEKGDL ISWDDLGQTK TILPDQDLTS MKYSSHFLYA LNKKGEILVI
260 270 280 290 300
PIRTPDLIAS QVSSRRSKLL PWKTKLRYDW KLQTNQIFNG KEGEKRVVQF
310 320 330 340 350
DAGSHHLVLL SNLGKAYCCA TGNDQKQAQV SKGQFGIPTF SQFDEFPPNN
360 370 380 390 400
QLFEIELLNK FKHEGEDVVR KREIKKIACG SYHTLAIDKT GEIYAFGWNR
410 420 430 440 450
FGQLALPISY NLEYVSFPRS VTHAFKPHFP GMTNWKCVDI HCDDETSFVT
460 470 480 490 500
IRKPGSTSDH HYFAFGNGLF GELGNNTFKN SQCDPIKIKS DDKKLTNWSC
510 520 530 540 550
GSHCVFTETE QENEVIAWGN NDHGQLGIGK KTMKCAKPMN IPEVLKPGQD
560 570 580
TTDLDSIYNS KLHLKKEQRV VTNGNKSCLY WRV
Length:583
Mass (Da):66,690
Last modified:November 1, 1996 - v1
Checksum:iB2EE61451F2A9948
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti160 – 1601P → L in AAU09761 (PubMed:17322287).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z73249 Genomic DNA. Translation: CAA97635.1.
Z73250 Genomic DNA. Translation: CAA97637.1.
U53880 Genomic DNA. Translation: AAB67597.1.
AY723844 Genomic DNA. Translation: AAU09761.1.
BK006945 Genomic DNA. Translation: DAA09393.1.
PIRiS64909.
RefSeqiNP_013178.1. NM_001181964.1.

Genome annotation databases

EnsemblFungiiYLR077W; YLR077W; YLR077W.
GeneIDi850766.
KEGGisce:YLR077W.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z73249 Genomic DNA. Translation: CAA97635.1.
Z73250 Genomic DNA. Translation: CAA97637.1.
U53880 Genomic DNA. Translation: AAB67597.1.
AY723844 Genomic DNA. Translation: AAU09761.1.
BK006945 Genomic DNA. Translation: DAA09393.1.
PIRiS64909.
RefSeqiNP_013178.1. NM_001181964.1.

3D structure databases

ProteinModelPortaliQ08023.
SMRiQ08023. Positions 295-546.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi31350. 12 interactions.
DIPiDIP-4474N.
IntActiQ08023. 2 interactions.
MINTiMINT-504101.

Proteomic databases

MaxQBiQ08023.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYLR077W; YLR077W; YLR077W.
GeneIDi850766.
KEGGisce:YLR077W.

Organism-specific databases

EuPathDBiFungiDB:YLR077W.
SGDiS000004067. FMP25.

Phylogenomic databases

HOGENOMiHOG000111193.
InParanoidiQ08023.
OMAiSPEYKEQ.
OrthoDBiEOG092C12QD.

Enzyme and pathway databases

BioCyciYEAST:G3O-32228-MONOMER.

Miscellaneous databases

PROiQ08023.

Family and domain databases

Gene3Di2.130.10.30. 2 hits.
InterProiIPR009091. RCC1/BLIP-II.
IPR000408. Reg_chr_condens.
[Graphical view]
PfamiPF00415. RCC1. 1 hit.
[Graphical view]
SUPFAMiSSF50985. SSF50985. 2 hits.
PROSITEiPS00626. RCC1_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiFMP25_YEAST
AccessioniPrimary (citable) accession number: Q08023
Secondary accession number(s): D6VY77, Q66R51, Q7LI62
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 25, 2006
Last sequence update: November 1, 1996
Last modified: September 7, 2016
This is version 105 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome XII
    Yeast (Saccharomyces cerevisiae) chromosome XII: entries and gene names

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.