Q07YH6 (RLMG_SHEFN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Ribosomal RNA large subunit methyltransferase G
EC=2.1.1.174

Alternative name(s):
23S rRNA m2G1835 methyltransferase
rRNA (guanine-N(2)-)-methyltransferase RlmG

Gene names

Name:	rlmG
Ordered Locus Names:	Sfri_3101

Organism

Shewanella frigidimarina (strain NCIMB 400) [Complete proteome] [HAMAP]

Taxonomic identifier

318167 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Alteromonadales › Shewanellaceae › Shewanella

Protein attributes

Sequence length	392 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Specifically methylates the guanosine in position 1835 (m2G1835) of 23S rRNA By similarity. HAMAP MF_01859
Catalytic activity	S-adenosyl-L-methionine + guanosine(1835) in 23S rRNA = S-adenosyl-L-homocysteine + N(2)-methylguanosine(1835) in 23S rRNA. HAMAP MF_01859
Subcellular location	Cytoplasm Potential HAMAP MF_01859.
Sequence similarities	Belongs to the methyltransferase superfamily. RlmG family.

Ontologies

Keywords
Biological process	rRNA processing
Cellular component	Cytoplasm
Ligand	S-adenosyl-L-methionine
Molecular function	Methyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	nucleic acid binding Inferred from electronic annotation. Source: InterPro rRNA (guanine-N2-)-methyltransferase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 392	392	Ribosomal RNA large subunit methyltransferase G HAMAP MF_01859		PRO_0000366509

Sequences

	Sequence		Length	Mass (Da)
	Q07YH6 [UniParc]. Last modified October 31, 2006. Version 1. Checksum: EC646F5979966691	FASTA	392	43,460
	10 20 30 40 50 60 MTTQFACSGI ELELFRYPSQ QASNLQAWDA ADEHLVKYLI DTEITATTTA ILNDNFGALT 70 80 90 100 110 120 CALTMQYPHS ELLVETDAKT SLLGYQQNLL HNKLASTNIH WLNSRETLPQ NIQLVLMKLP 130 140 150 160 170 180 KNLHYFGQQL ARLSTVLPAG TQILIGAKAK SINPALLASI EKNLGPASAS LAWKKTRVIS 190 200 210 220 230 240 CISDGKKRSL AKAVSWNVDE LKLTISNLAN VFAANKLDIG ARIMLDNMPK GEFKHIIDLG 250 260 270 280 290 300 CGNGILGLHA KQCYPNAQIH FVDDSDMAIA SAKHNWQANE LDTPSQDLQS QDPQTEQMPQ 310 320 330 340 350 360 AFFHWDDCLS NLPADVEPDL VICNPPFHQG EAITDHIAWQ MFVDAHKRLK KGGLLHIVGN 370 380 390 RHLAYHVKIN RIFKNCTTVA SNGKFVILQA IK

References

[1]

"Complete sequence of Shewanella frigidimarina NCIMB 400." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Fredrickson J.K., Kolker E., McCuel L.A., DiChristina T., Nealson K.H., Newman D., Tiedje J.M. , Zhou J., Romine M.F., Culley D.E., Serres M., Chertkov O., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Richardson P. Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: NCIMB 400.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000447 Genomic DNA. Translation: ABI72938.1.
RefSeq	YP_751777.1. NC_008345.1.
3D structure databases
ProteinModelPortal	Q07YH6.
ModBase	Search...
Protein-protein interaction databases
STRING	Q07YH6.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4280004.
GenomeReviews	Gene locus Sfri_3101 in contig CP000447_GR.
KEGG	sfr:Sfri_3101.
NMPDR	fig|318167.10.peg.2976.
PATRIC	23500347. VBISheFri14343_3214.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG2813.
HOGENOM	HBG321931.
OMA	NRHLGYH.
PhylomeDB	Q07YH6.
ProtClustDB	CLSK906089.
Family and domain databases
HAMAP	MF_01859. 23SrRNA_methyltr_G. [Tree]
InterPro	IPR002052. DNA_methylase_N6_adenine_CS. IPR017237. rRNA_m2G-MeTrfase_RsmD. IPR007848. Small_mtfrase. [Graphical view]
KO	K00564.
Pfam	PF05175. MTS. 1 hit. [Graphical view]
PIRSF	PIRSF037565. RRNA_m2G_Mtase_RsmD_prd. 1 hit.
ProtoNet	Search...

Entry information

Entry name

RLMG_SHEFN

Accession

Primary (citable) accession number: Q07YH6

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 24, 2009
Last sequence update:	October 31, 2006
Last modified:	January 25, 2012
This is version 37 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program