Reviewed, UniProtKB/Swiss-Prot Q07Y94 (CYSC_SHEFN)

Names and origin

Protein names

Recommended name:
    Adenylyl-sulfate kinase
    EC=2.7.1.25
Alternative name(s):
    APS kinase
    Adenosine-5'-phosphosulfate kinase
    ATP adenosine-5'-phosphosulfate 3'-phosphotransferase

Gene names

Name:	cysC
Ordered Locus Names:	Sfri_3184

Organism

Shewanella frigidimarina (strain NCIMB 400) [Complete proteome] [HAMAP]

Taxonomic identifier

318167 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Alteromonadales › Shewanellaceae › Shewanella

Protein attributes

Sequence length	207 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Catalyzes the synthesis of activated sulfate. HAMAP MF_00065
Catalytic activity	ATP + adenylyl sulfate = ADP + 3'-phosphoadenylyl sulfate. HAMAP MF_00065
Pathway	Sulfur metabolism; hydrogen sulfide biosynthesis; sulfite from sulfate: step 2/3. HAMAP MF_00065
Sequence similarities	Belongs to the APS kinase family.

Ontologies

Keywords
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
PTM	Phosphoprotein
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	sulfate assimilation Inferred from electronic annotation. Source: HAMAP
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP adenylylsulfate kinase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 207	207	Adenylyl-sulfate kinase HAMAP MF_00065		PRO_1000009025
Regions
	Nucleotide binding	31 – 38	8	ATP By similarity
Sites
	Active site	105	1	Phosphoserine intermediate By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q07Y94-1 [UniParc]. Last modified October 31, 2006. Version 1. Checksum: 21E01D46448CA4EB	FASTA	207	22,580
	10 20 30 40 50 60 MSNIVWHQHA IDQAARGAQK GQNPVLLWFT GLSGSGKSTL AGALERALFE HGFHTYLLDG 70 80 90 100 110 120 DNVRHGLCKD LGFSIEDRDE NLRRVGEVAK LMVDSGLVVL SAFISPTREE RDRVRALFPQ 130 140 150 160 170 180 GQFVEVHVST PLSVCESRDP KGLYAKARKG EITNFTGISS PYEVPESAEL TIDTSKGDLD 190 200 TQVHGLLAYL KAIDVLNPPR EIAGAGI

References

[1]

"Complete sequence of Shewanella frigidimarina NCIMB 400." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Fredrickson J.K., Kolker E., McCuel L.A., DiChristina T., Nealson K.H., Newman D., Tiedje J.M. , Zhou J., Romine M.F., Culley D.E., Serres M., Chertkov O., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Richardson P. Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000447 Genomic DNA. Translation: ABI73020.1.
RefSeq	YP_751859.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	4280086.
GenomeReviews	Gene locus Sfri_3184 in contig CP000447_GR.
KEGG	sfr:Sfri_3184.
NMPDR	fig|318167.10.peg.3057.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q07Y94.
OMA	Q07Y94. IVWHQHS.
Family and domain databases
HAMAP	MF_00065. [Tree]
InterPro	IPR002891. APS_kinase_C. [Graphical view]
Pfam	PF01583. APS_kinase. 1 hit. [Graphical view]
ProDom	PD002350. APS_kinase. 1 hit. [Graphical view] [Entries sharing at least one domain]
TIGRFAMs	TIGR00455. apsK. 1 hit.
ProtoNet	Search...

Entry information

Entry name

CYSC_SHEFN

Accession

Primary (citable) accession number: Q07Y94

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	October 31, 2006
Last modified:	June 16, 2009
This is version 19 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)