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Q07WM5 (SYR_SHEFN) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 51. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Arginine--tRNA ligase

EC=6.1.1.19
Alternative name(s):
Arginyl-tRNA synthetase
Short name=ArgRS
Gene names
Name:argS
Ordered Locus Names:Sfri_3762
OrganismShewanella frigidimarina (strain NCIMB 400) [Complete proteome] [HAMAP]
Taxonomic identifier318167 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesShewanellaceaeShewanella

Protein attributes

Sequence length581 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP-Rule MF_00123

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00123

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00123.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processarginyl-tRNA aminoacylation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

arginine-tRNA ligase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 581581Arginine--tRNA ligase HAMAP-Rule MF_00123
PRO_1000018115

Regions

Motif126 – 13611"HIGH" region HAMAP-Rule MF_00123

Sequences

Sequence LengthMass (Da)Tools
Q07WM5 [UniParc].

Last modified October 31, 2006. Version 1.
Checksum: F61D735E63EF6B35

FASTA58164,702
        10         20         30         40         50         60 
MKSHIESLLE QTIESFKQQG IVPADFQARI QVDRTKDKSH GDLATNLAMM LTKVAKKNPR 

        70         80         90        100        110        120 
ELAQLIIDTL PASSYVAKVE IAGPGFINFF IDDNALANQL QQALTSDHLG VALPTKQTIV 

       130        140        150        160        170        180 
VDYSSPNLAK EMHVGHLRST IIGDSVVRAL EYLGHNVIRQ NHVGDWGTQF GMLLALMEEL 

       190        200        210        220        230        240 
RAANGEQAKM ELSDLESFYR AAKVRFDEST EFATRARQLV VALQSGDEYC NKLWREFNDI 

       250        260        270        280        290        300 
SLSHCHDVYK RLGVSLTRAD VHGESAYNAD LAQVVKDLDA QGLLSESNGA KVVFQEAFRN 

       310        320        330        340        350        360 
KEGEPLPVII QKADGGYLYA TSDLAAMRYR SNVLKADRAM YFVDLRQALH FQQVFSLAKL 

       370        380        390        400        410        420 
AKFVRPEMSL EHTGFGTMNG EDGRPFKTRS GGVVKLVDLL DEADVRALEL VRSKNPDMDE 

       430        440        450        460        470        480 
ATLTEIARVV GISSVKYADL SKNRTSDYIF SFEQMLSFEG NTAPYLLYAY TRVAGIFKRA 

       490        500        510        520        530        540 
TDIDLSQAKI VLEHEKEKDL GTKLAQFGEV LTRMTDKGLP HVLCGYLYEL ASEFSSFYEA 

       550        560        570        580 
CPVLAAETEA QKQSRLLLAQ LTAKTLKTGL SLLGIETLER M 

« Hide

References

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000447 Genomic DNA. Translation: ABI73589.1.
RefSeqYP_752428.1. NC_008345.1.

3D structure databases

ProteinModelPortalQ07WM5.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING318167.Sfri_3762.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABI73589; ABI73589; Sfri_3762.
GeneID4280655.
KEGGsfr:Sfri_3762.
PATRIC23501713. VBISheFri14343_3893.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0018.
HOGENOMHOG000247212.
KOK01887.
OMANPNGPLH.
OrthoDBEOG6JB13C.
ProtClustDBPRK01611.

Enzyme and pathway databases

BioCycSFRI318167:GIXS-3880-MONOMER.

Family and domain databases

Gene3D1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPMF_00123. Arg_tRNA_synth.
InterProIPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERPTHR11956. PTHR11956. 1 hit.
PfamPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSPR01038. TRNASYNTHARG.
SMARTSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsTIGR00456. argS. 1 hit.
PROSITEPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSYR_SHEFN
AccessionPrimary (citable) accession number: Q07WM5
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: October 31, 2006
Last modified: April 16, 2014
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries