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Q07V74

- TRMB_RHOP5

UniProt

Q07V74 - TRMB_RHOP5

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Protein
tRNA (guanine-N(7)-)-methyltransferase
Gene
trmB, RPE_0200
Organism
Rhodopseudomonas palustris (strain BisA53)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA By similarity.UniRule annotation

Catalytic activityi

S-adenosyl-L-methionine + guanine(46) in tRNA = S-adenosyl-L-homocysteine + N(7)-methylguanine(46) in tRNA.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei79 – 791S-adenosyl-L-methionine By similarity
Binding sitei104 – 1041S-adenosyl-L-methionine By similarity
Binding sitei131 – 1311S-adenosyl-L-methionine By similarity
Active sitei153 – 1531 By similarity
Binding sitei153 – 1531S-adenosyl-L-methionine By similarity
Binding sitei157 – 1571Substrate By similarity
Binding sitei189 – 1891Substrate By similarity

GO - Molecular functioni

  1. tRNA (guanine-N7-)-methyltransferase activity Source: UniProtKB-HAMAP
Complete GO annotation...

GO - Biological processi

    Complete GO annotation...

    Keywords - Molecular functioni

    Methyltransferase, Transferase

    Keywords - Biological processi

    tRNA processing

    Keywords - Ligandi

    S-adenosyl-L-methionine

    Enzyme and pathway databases

    BioCyciRPAL316055:GHR9-203-MONOMER.
    UniPathwayiUPA00989.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    tRNA (guanine-N(7)-)-methyltransferase (EC:2.1.1.33)
    Alternative name(s):
    tRNA (guanine(46)-N(7))-methyltransferase
    tRNA(m7G46)-methyltransferase
    Gene namesi
    Name:trmB
    Ordered Locus Names:RPE_0200
    OrganismiRhodopseudomonas palustris (strain BisA53)
    Taxonomic identifieri316055 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBradyrhizobiaceaeRhodopseudomonas
    ProteomesiUP000000654: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 250250tRNA (guanine-N(7)-)-methyltransferaseUniRule annotation
    PRO_0000288213Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi316055.RPE_0200.

    Structurei

    3D structure databases

    ProteinModelPortaliQ07V74.

    Family & Domainsi

    Sequence similaritiesi

    Phylogenomic databases

    eggNOGiCOG0220.
    HOGENOMiHOG000073969.
    KOiK03439.
    OMAiRAFYGRR.
    OrthoDBiEOG6K6VBC.

    Family and domain databases

    Gene3Di3.40.50.150. 1 hit.
    HAMAPiMF_01057. tRNA_methyltr_TrmB.
    InterProiIPR029063. SAM-dependent_MTases-like.
    IPR003358. tRNA_(Gua-N-7)_MeTrfase.
    [Graphical view]
    PfamiPF02390. Methyltransf_4. 1 hit.
    [Graphical view]
    SUPFAMiSSF53335. SSF53335. 1 hit.
    TIGRFAMsiTIGR00091. TIGR00091. 1 hit.
    PROSITEiPS51625. SAM_MT_TRMB. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q07V74-1 [UniParc]FASTAAdd to Basket

    « Hide

    MTPDDPRDAS DASLADATAD SASRGHGSFF GRRKGHKLRA HQAELIADLL    50
    PQLSFDLAAP PPADLRALFE PGVDQVKLEI GFGGGEHLVA EAEAHPATGF 100
    IGCEPYVNGM AKILAQIEAR GIRNIRLFAG DAAELLAWAP KASLARIDLI 150
    HPDPWPKRRH WKRRFVQDAT VTAMARALRD DGEFRFVCDI DDYSAWTLSH 200
    LTRSPDFAWT AERARDWQNP FAGYTMTRYG RKAEREGRRA AYLHFQRNAA 250
    Length:250
    Mass (Da):27,846
    Last modified:October 31, 2006 - v1
    Checksum:iD21C4991F89731EF
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000463 Genomic DNA. Translation: ABJ04160.1.
    RefSeqiWP_011661654.1. NC_008435.1.
    YP_779140.1. NC_008435.1.

    Genome annotation databases

    EnsemblBacteriaiABJ04160; ABJ04160; RPE_0200.
    GeneIDi4358501.
    KEGGirpe:RPE_0200.
    PATRICi23254868. VBIRhoPal93214_0200.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000463 Genomic DNA. Translation: ABJ04160.1 .
    RefSeqi WP_011661654.1. NC_008435.1.
    YP_779140.1. NC_008435.1.

    3D structure databases

    ProteinModelPortali Q07V74.
    ModBasei Search...

    Protein-protein interaction databases

    STRINGi 316055.RPE_0200.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABJ04160 ; ABJ04160 ; RPE_0200 .
    GeneIDi 4358501.
    KEGGi rpe:RPE_0200.
    PATRICi 23254868. VBIRhoPal93214_0200.

    Phylogenomic databases

    eggNOGi COG0220.
    HOGENOMi HOG000073969.
    KOi K03439.
    OMAi RAFYGRR.
    OrthoDBi EOG6K6VBC.

    Enzyme and pathway databases

    UniPathwayi UPA00989 .
    BioCyci RPAL316055:GHR9-203-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.150. 1 hit.
    HAMAPi MF_01057. tRNA_methyltr_TrmB.
    InterProi IPR029063. SAM-dependent_MTases-like.
    IPR003358. tRNA_(Gua-N-7)_MeTrfase.
    [Graphical view ]
    Pfami PF02390. Methyltransf_4. 1 hit.
    [Graphical view ]
    SUPFAMi SSF53335. SSF53335. 1 hit.
    TIGRFAMsi TIGR00091. TIGR00091. 1 hit.
    PROSITEi PS51625. SAM_MT_TRMB. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: BisA53.

    Entry informationi

    Entry nameiTRMB_RHOP5
    AccessioniPrimary (citable) accession number: Q07V74
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 29, 2007
    Last sequence update: October 31, 2006
    Last modified: September 3, 2014
    This is version 52 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3

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