Q07U47 (Q07U47_RHOP5) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
NH(3)-dependent NAD(+) synthetase HAMAP MF_00193 RuleBase RU003812
EC=6.3.1.5 HAMAP MF_00193 RuleBase RU003812

Gene names

Name:	nadE HAMAP MF_00193
Ordered Locus Names:	RPE_0579

Organism

Rhodopseudomonas palustris (strain BisA53) [Complete proteome] [HAMAP]

Taxonomic identifier

316055 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Bradyrhizobiaceae › Rhodopseudomonas

Protein attributes

Sequence length	345 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + deamido-NAD+ + NH3 = AMP + diphosphate + NAD+. HAMAP MF_00193 RuleBase RU003812 SAAS SAAS003694
Pathway	Cofactor biosynthesis; NAD(+) biosynthesis; NAD(+) from deamido-NAD(+) (ammonia route): step 1/1. HAMAP MF_00193 SAAS SAAS003694 RuleBase RU004252
Sequence similarities	Belongs to the NAD synthetase family. HAMAP MF_00193 RuleBase RU003811

Ontologies

Keywords
Ligand	ATP-binding SAAS SAAS003694 HAMAP MF_00193 RuleBase RU003811 NAD HAMAP MF_00193 SAAS SAAS003694 RuleBase RU003811 Nucleotide-binding
Molecular function	Ligase SAAS SAAS003694 HAMAP MF_00193 RuleBase RU003811 EMBL ABJ04537.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	NAD biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP NAD+ synthase (glutamine-hydrolyzing) activity Inferred from electronic annotation. Source: InterPro NAD+ synthase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Regions
	Nucleotide binding	54 – 61	8	ATP By similarity HAMAP MF_00193
Sites
	Active site	56	1	By similarity HAMAP MF_00193

Sequences

	Sequence		Length	Mass (Da)
	Q07U47 [UniParc]. Last modified October 31, 2006. Version 1. Checksum: 654927B83686B95C	FASTA	345	38,079
	10 20 30 40 50 60 MNTIFRDPAP ASAEPLADFS LSLRIDAEAE TARIVEAIRT QVLRRLKRRG AVLGLSGGID 70 80 90 100 110 120 SSVTVALCVR ALGPDKVLAL LMPEHDSDPD SLRLGRLMAE TVGVEAVTED IAPILAGAGC 130 140 150 160 170 180 YQRRDAFIRA VVPEFGPGWG CKVVIANSLG ASYSITSLVV QSPDGEQRKV RLPLDLYLGI 190 200 210 220 230 240 IAATNMKQRT RKQVEYFHAD RLNFAVAGTP NLLEYDQGFF VKNGDGAADF KPIAHLYKSQ 250 260 270 280 290 300 VYQLADYLGV PDEIRRRPPT TDTWSLPQTQ EEFYFSLPYQ RMDLCLYALN NGVPAEIAAP 310 320 330 340 VTGLTPVQIK QVWRDIEAKR RATRYLHEPP LLVEGACVKE IEEVV

References

[1]

"Complete sequence of Rhodopseudomonas palustris BisA53." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M. , Hauser L., Pelletier D.A., Kyrpides N., Kim E., Harwood C.S., Oda Y., Richardson P. Submitted (SEP-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: BisA53.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000463 Genomic DNA. Translation: ABJ04537.1.
RefSeq	YP_779517.1. NC_008435.1.
3D structure databases
ProteinModelPortal	Q07U47.
ModBase	Search...
Protein-protein interaction databases
STRING	Q07U47.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4359104.
GenomeReviews	Gene locus RPE_0579 in contig CP000463_GR.
KEGG	rpe:RPE_0579.
PATRIC	23255650. VBIRhoPal93214_0587.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0171.
HOGENOM	HBG351567.
OMA	AHLYKSQ.
ProtClustDB	PRK00876.
Enzyme and pathway databases
BioCyc	RPAL316055:RPE_0579-MONOMER.
Family and domain databases
HAMAP	MF_00193. NadE. [Tree]
InterPro	IPR022310. NAD/GMP_synthase. IPR003694. NAD_synthase. IPR022926. NH(3)-dep_NAD(+)_synth. IPR014729. Rossmann-like_a/b/a_fold. [Graphical view]
Gene3D	G3DSA:3.40.50.620. Rossmann-like_a/b/a_fold. 2 hits.
KO	K01916.
Pfam	PF02540. NAD_synthase. 2 hits. [Graphical view]
TIGRFAMs	TIGR00552. NadE. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q07U47_RHOP5

Accession

Primary (citable) accession number: Q07U47

Entry history

Integrated into UniProtKB/TrEMBL:	October 31, 2006
Last sequence update:	October 31, 2006
Last modified:	December 14, 2011
This is version 35 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)