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Q07QM0 (Q07QM0_RHOP5) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 40. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
4-hydroxy-3-methylbut-2-enyl diphosphate reductase 1 HAMAP MF_00191
EC=1.17.1.2 HAMAP MF_00191
Gene names
Name:ispH1 HAMAP MF_00191
Ordered Locus Names:RPE_1816
OrganismRhodopseudomonas palustris (strain BisA53) [Complete proteome] [HAMAP]
Taxonomic identifier316055 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Bradyrhizobiaceae › Rhodopseudomonas

Protein attributes

Sequence length314 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) By similarity. HAMAP MF_00191 SAAS SAAS003451

Catalytic activity

Dimethylallyl diphosphate + NAD(P)+ + H2O = (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate + NAD(P)H. HAMAP MF_00191 SAAS SAAS003451

Isopentenyl diphosphate + NAD(P)+ + H2O = (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate + NAD(P)H. HAMAP MF_00191 SAAS SAAS003451

Cofactor

Binds 1 3Fe-4S cluster By similarity. HAMAP MF_00191

Pathway

Isoprenoid biosynthesis; dimethylallyl diphosphate biosynthesis; dimethylallyl diphosphate from (2E)-4-hydroxy-3-methylbutenyl diphosphate: step 1/1. HAMAP MF_00191 SAAS SAAS003451

Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via DXP pathway; isopentenyl diphosphate from 1-deoxy-D-xylulose 5-phosphate: step 6/6. HAMAP MF_00191 SAAS SAAS003451

Sequence similarities

Belongs to the IspH family. HAMAP MF_00191

Sequences

Sequence LengthMass (Da)Tools
Q07QM0 [UniParc].

Last modified October 31, 2006. Version 1.
Checksum: 8F9076AE08D21817

FASTA31433,698
        10         20         30         40         50         60 
MYNVRPLEVF LAQPRGFCAG VVRAIEIVER ALEKYGPPVY VRHEIVHNKY VVESLKAKGA 

        70         80         90        100        110        120 
IFVEDLSAVP PKAVTVFSAH GVARSVEEEA AQRGLPVLNA TCPLVTKVHN QGKRYMAKGR 

       130        140        150        160        170        180 
VLILIGHAGH PEVEGTMGQV PGPVLLVQNV EDVAGLTLPS QTPVAYITQT TLSVDDTKDI 

       190        200        210        220        230        240 
IAALSERFPD IQGPDTRDIC YATQNRQSAV RDLSKLVDLI LVVGANNSSN SNRLREIGTE 

       250        260        270        280        290        300 
AGIPSYLIAD GSELDPDWLT GVKAVGITAG ASAPEVLVDD VIEALRRIGP VVVSVLPGRE 

       310 
ENIEFLLPPE LAPA

« Hide

References

[1]"Complete sequence of Rhodopseudomonas palustris BisA53."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M. expand/collapse author list , Hauser L., Pelletier D.A., Kyrpides N., Kim E., Harwood C.S., Oda Y., Richardson P.
Submitted (SEP-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: BisA53.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000463 Genomic DNA. Translation: ABJ05764.1.
RefSeqYP_780744.1. NC_008435.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGQ07QM0.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4358395.
GenomeReviewsGene locus RPE_1816 in contig CP000463_GR.
KEGGrpe:RPE_1816.
PATRIC23258196. VBIRhoPal93214_1850.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0761.
HOGENOMHBG335228.
OMAHNQGKRY.
ProtClustDBPRK01045.

Enzyme and pathway databases

BioCycRPAL316055:RPE_1816-MONOMER.

Family and domain databases

HAMAPMF_00191. IspH.
[Tree]
InterProIPR003451. LytB.
[Graphical view]
KOK03527.
PfamPF02401. LYTB. 1 hit.
[Graphical view]
TIGRFAMsTIGR00216. IspH_lytB. 1 hit.
ProtoNetSearch...

Entry information

Entry nameQ07QM0_RHOP5
AccessionPrimary (citable) accession number: Q07QM0
Entry history
Integrated into UniProtKB/TrEMBL: October 31, 2006
Last sequence update: October 31, 2006
Last modified: December 14, 2011
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info