Reviewed, UniProtKB/Swiss-Prot Q07QK9 (DNAE2_RHOP5)

Names and origin

Protein names

Recommended name:
    Error-prone DNA polymerase
    EC=2.7.7.7

Gene names

Name:	dnaE2
Ordered Locus Names:	RPE_1827

Organism

Rhodopseudomonas palustris (strain BisA53) [Complete proteome] [HAMAP]

Taxonomic identifier

316055 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Bradyrhizobiaceae › Rhodopseudomonas

Protein attributes

Sequence length	1153 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase By similarity.
Catalytic activity	Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
Subcellular location	CytoplasmProbable.
Sequence similarities	Belongs to the DNA polymerase type-C family. DnaE2 subfamily.

Ontologies

Keywords
Biological process	DNA damage DNA repair DNA replication
Cellular component	Cytoplasm
Molecular function	DNA-directed DNA polymerase Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	DNA replication Inferred from electronic annotation. Source: InterPro error-prone DNA repair Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: HAMAP
Molecular function	3'-5' exonuclease activity Inferred from electronic annotation. Source: InterPro DNA binding Inferred from electronic annotation. Source: InterPro DNA-directed DNA polymerase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 1153	1153	Error-prone DNA polymerase		PRO_1000070596

Sequences

	Sequence		Length	Mass (Da)
	Q07QK9-1 [UniParc]. Last modified October 31, 2006. Version 1. Checksum: 85A2C7AC6B3E3148	FASTA	1,153	128,709
	10 20 30 40 50 60 MTAPRYAEIG VTSNFSFLEG GSHPQEFVQQ ASALGLAAIG IADRNTLAGV VRAYSELDNE 70 80 90 100 110 120 ELFYKPKLLI GARLCFADGT PDILAYPTDR AAYGRLCRLL SAGKLRAGKG ECHLSFADLE 130 140 150 160 170 180 AFTKTSTPSW PGLSRPSTSS SKAVQVSVDA RVKPGHDEAK RAAGESRLLL VLMPPYRFQS 190 200 210 220 230 240 HEITAALTRL TALQGAGVWL ALVPYYRGDD KRRLARLQRI AAAARVPGIA SNDVLYHHES 250 260 270 280 290 300 RRALQDVLTC VRDKTTIDKA GRLLESNAER YLKPTEEMAR LFRADPDAIA ETLRFADRIS 310 320 330 340 350 360 FTLDELKYQY PDEPVPPGKT AQQHLKDLTE QGIAEYFPNG IDAKLRATID KELTIIAHRQ 370 380 390 400 410 420 YAPYFLTVHD IVRYARSQNI LCQGRGSAAN SAVCYVLGIT CVDPTEIDLL FERFVSEERD 430 440 450 460 470 480 EPPDIDVDFE HSRREEVMQY IYRRYGRHRA AIVSTVIHYR PRSAIRDVGK ALGLSEDVTA 490 500 510 520 530 540 ALADTVWGSW GKGLNEMQVR QAGLDPTNPM IVRAIDLATE LIGFPRHLSQ HVGGYVLTQD 550 560 570 580 590 600 RLDEFVPIGN AAMEERTFIE WDKDDIDAVK MMKVDVLALG MLTCIRKGFD LIAQHKGKRY 610 620 630 640 650 660 ELADIKSEDD NEVYKMLQRG ESVGVFQVES RAQMNMLPRL RPRCFYDLVI EVAIVRPGPI 670 680 690 700 710 720 QGDMVHPYLR RRNGQEPVVY PSPAGHAGEA NELKTILGKT LGVPLFQEQA MRIAIEAAHF 730 740 750 760 770 780 TPDEANQLRR AMATFRNVGT IGKFEAKMTG NLVARGYDPV FAQNCFEQIK GFGSYGFPES 790 800 810 820 830 840 HAASFAKLVY VSAWLKHAHP DAFCCALLNS QPMGFYAPAQ IVGDARQNGV EIRGVDVAYS 850 860 870 880 890 900 FSQNTLEERC GQHHAVRLGF RQIDGFRWAD FDEANLWQAR GDAPPEDWGA RIVEAREKSP 910 920 930 940 950 960 FTSLEQFARA TALPKRALIL LADADAFRSL KLDRRAALWA VRRLPDDVPL PLFEVAKARE 970 980 990 1000 1010 1020 QQDENAAPLP LMPLAEHVVA DYQTVRLSLK GHPMQFLRAL FAAEGVNTCR AVSETRRNGR 1030 1040 1050 1060 1070 1080 RARCAGVVLV RQRPGSAKGV VFITLEDETG IANLVVWPAV MEKFRKEVMG ARLLWVEGKI 1090 1100 1110 1120 1130 1140 QASPEGVVHL VAEELVDRSA EMARLSDELI APSASTEREA PLNDDRRDHP DLPAQQIRHP 1150 RNVRILPPSR DFH

References

[1]

"Complete sequence of Rhodopseudomonas palustris BisA53." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M. , Hauser L., Pelletier D.A., Kyrpides N., Kim E., Harwood C.S., Oda Y., Richardson P. Submitted (SEP-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000463 Genomic DNA. Translation: ABJ05775.1.
RefSeq	YP_780755.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	4359268.
GenomeReviews	Gene locus RPE_1827 in contig CP000463_GR.
KEGG	rpe:RPE_1827.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q07QK9.
Family and domain databases
HAMAP	MF_01902. [Tree]
InterPro	IPR011708. DNA_pol3_alpha. IPR004365. NA_bd_OB_tRNA-helicase. IPR004013. PHP_C. IPR003141. PHP_N. IPR004805. PolC_alpha. [Graphical view]
Pfam	PF07733. DNA_pol3_alpha. 1 hit. PF02811. PHP. 1 hit. PF01336. tRNA_anti. 1 hit. [Graphical view]
SMART	SM00481. POLIIIAc. 1 hit. [Graphical view]
TIGRFAMs	TIGR00594. polc. 1 hit.
ProtoNet	Search...

Entry information

Entry name

DNAE2_RHOP5

Accession

Primary (citable) accession number: Q07QK9

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 5, 2008
Last sequence update:	October 31, 2006
Last modified:	November 25, 2008
This is version 16 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)