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Protein

Holliday junction ATP-dependent DNA helicase RuvA

Gene

ruvA

Organism
Rhodopseudomonas palustris (strain BisA53)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.UniRule annotation

Catalytic activityi

ATP + H2O = ADP + phosphate.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-binding, Helicase, Hydrolase
Biological processDNA damage, DNA recombination, DNA repair, SOS response
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciRPAL316055:G1G7C-4804-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Holliday junction ATP-dependent DNA helicase RuvAUniRule annotation (EC:3.6.4.12UniRule annotation)
Gene namesi
Name:ruvAUniRule annotation
Ordered Locus Names:RPE_4769
OrganismiRhodopseudomonas palustris (strain BisA53)
Taxonomic identifieri316055 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBradyrhizobiaceaeRhodopseudomonas
Proteomesi

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000025281 – 205Holliday junction ATP-dependent DNA helicase RuvAAdd BLAST205

Proteomic databases

PRIDEiQ07H96

Interactioni

Subunit structurei

Forms a complex with RuvB.UniRule annotation

Protein-protein interaction databases

STRINGi316055.RPE_4769

Structurei

3D structure databases

ProteinModelPortaliQ07H96
SMRiQ07H96
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the RuvA family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105KA4 Bacteria
COG0632 LUCA
HOGENOMiHOG000057115
KOiK03550
OMAiDCHGVGY
OrthoDBiPOG091H02EF

Family and domain databases

HAMAPiMF_00031 DNA_helic_RuvA, 1 hit
InterProiView protein in InterPro
IPR013849 DNA_helicase_Holl-junc_RuvA_I
IPR003583 Hlx-hairpin-Hlx_DNA-bd_motif
IPR012340 NA-bd_OB-fold
IPR000085 RuvA
IPR010994 RuvA_2-like
IPR011114 RuvA_C
IPR036267 RuvA_C_sf
PANTHERiPTHR33796 PTHR33796, 1 hit
PfamiView protein in Pfam
PF07499 RuvA_C, 1 hit
PF01330 RuvA_N, 1 hit
SMARTiView protein in SMART
SM00278 HhH1, 2 hits
SUPFAMiSSF46929 SSF46929, 1 hit
SSF47781 SSF47781, 1 hit
SSF50249 SSF50249, 1 hit
TIGRFAMsiTIGR00084 ruvA, 1 hit

Sequencei

Sequence statusi: Complete.

Q07H96-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIGKLKGLID SYGEDYVILD VQGVGYQVHC ASRTLQALPQ AGEAAVLSIE
60 70 80 90 100
TYVREDQIKL FGFRSDLERE WFRLLQTVQG VGAKVALSVL STLPPSDLAD
110 120 130 140 150
AIALRDKAAV ARTPGVGPKV AERIVTELKD KAPGFASVDP AVAHLSGAIE
160 170 180 190 200
ERSAPRPVAD AISALVNLGY GQPQAAAAIA AAARSAGDAA QTAQLIKLGL

KELSK
Length:205
Mass (Da):21,471
Last modified:October 31, 2006 - v1
Checksum:iD255C860CC226873
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000463 Genomic DNA Translation: ABJ08688.1
RefSeqiWP_011666143.1, NC_008435.1

Genome annotation databases

EnsemblBacteriaiABJ08688; ABJ08688; RPE_4769
KEGGirpe:RPE_4769

Entry informationi

Entry nameiRUVA_RHOP5
AccessioniPrimary (citable) accession number: Q07H96
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: October 31, 2006
Last modified: May 23, 2018
This is version 72 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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