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Q07940

- GUN4_RUMAL

UniProt

Q07940 - GUN4_RUMAL

Protein

Endoglucanase 4

Gene

Eg IV

Organism
Ruminococcus albus
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 69 (01 Oct 2014)
      Sequence version 1 (01 Feb 1995)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    Endohydrolysis of (1->4)-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.

    pH dependencei

    Optimum pH is 7.

    Temperature dependencei

    Optimum temperature is 40 degrees Celsius.

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei135 – 1351Proton donorBy similarity
    Active sitei222 – 2221NucleophileBy similarity

    GO - Molecular functioni

    1. cellulase activity Source: UniProtKB-EC

    GO - Biological processi

    1. cellulose catabolic process Source: UniProtKB-KW

    Keywords - Molecular functioni

    Glycosidase, Hydrolase

    Keywords - Biological processi

    Carbohydrate metabolism, Cellulose degradation, Polysaccharide degradation

    Protein family/group databases

    CAZyiGH5. Glycoside Hydrolase Family 5.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Endoglucanase 4 (EC:3.2.1.4)
    Alternative name(s):
    Cellulase 4
    Endo-1,4-beta-glucanase 4
    Endoglucanase IV
    Short name:
    EG-IV
    Gene namesi
    Name:Eg IV
    OrganismiRuminococcus albus
    Taxonomic identifieri1264 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesRuminococcaceaeRuminococcus

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 312312Endoglucanase 4PRO_0000184050Add
    BLAST

    Structurei

    3D structure databases

    ProteinModelPortaliQ07940.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Family and domain databases

    Gene3Di3.20.20.80. 1 hit.
    InterProiIPR001547. Glyco_hydro_5.
    IPR018087. Glyco_hydro_5_CS.
    IPR013781. Glyco_hydro_catalytic_dom.
    IPR017853. Glycoside_hydrolase_SF.
    [Graphical view]
    PfamiPF00150. Cellulase. 1 hit.
    [Graphical view]
    SUPFAMiSSF51445. SSF51445. 1 hit.
    PROSITEiPS00659. GLYCOSYL_HYDROL_F5. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q07940-1 [UniParc]FASTAAdd to Basket

    « Hide

    MLDKLKVING KLTAGEKPVR LFGLSTHGIA WYPEYICEES FNALKKDWRT    50
    NCIRIAMYTD EFRGYCKDGN KQHLKELIEK GVVIAEKLDM YVIVDWHVLC 100
    DQDPMKYIDE AEEFFSDMSK RFANKTNVIY EICNEPNCSG TWDKITEYAD 150
    RIIPIIRSNS PDALIVTGTS TWSQDIHCAL EKPLKWDNVM YSLHFYAATH 200
    KGTLRSRLER CIEAGLPVFI NEFNLCEASG KGDIDIDEAN AWYEVIDRLG 250
    LSCISWCLSN SGDTCGVFTQ NCTKLSGWTD EDIKTSGKII KGWFEAFADE 300
    ENTNEQCFRI DK 312
    Length:312
    Mass (Da):35,767
    Last modified:February 1, 1995 - v1
    Checksum:iA8BAADD9F93A8CBC
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB016777 Genomic DNA. Translation: BAA32286.1.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB016777 Genomic DNA. Translation: BAA32286.1 .

    3D structure databases

    ProteinModelPortali Q07940.
    ModBasei Search...
    MobiDBi Search...

    Protein family/group databases

    CAZyi GH5. Glycoside Hydrolase Family 5.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Family and domain databases

    Gene3Di 3.20.20.80. 1 hit.
    InterProi IPR001547. Glyco_hydro_5.
    IPR018087. Glyco_hydro_5_CS.
    IPR013781. Glyco_hydro_catalytic_dom.
    IPR017853. Glycoside_hydrolase_SF.
    [Graphical view ]
    Pfami PF00150. Cellulase. 1 hit.
    [Graphical view ]
    SUPFAMi SSF51445. SSF51445. 1 hit.
    PROSITEi PS00659. GLYCOSYL_HYDROL_F5. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Cloning and sequencing of a novel endo-1,4-beta-glucanase gene from Ruminococcus albus."
      Karita S., Morioka K., Kajino T., Sakka K., Shimada K., Ohmiya K.
      J. Ferment. Bioeng. 76:439-444(1993)
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], PROTEIN SEQUENCE OF 1-19.
      Strain: F-40.

    Entry informationi

    Entry nameiGUN4_RUMAL
    AccessioniPrimary (citable) accession number: Q07940
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 1, 1995
    Last sequence update: February 1, 1995
    Last modified: October 1, 2014
    This is version 69 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Direct protein sequencing

    Documents

    1. Glycosyl hydrolases
      Classification of glycosyl hydrolase families and list of entries
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3