Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Epsin-4

Gene

ENT4

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • clathrin binding Source: SGD

GO - Biological processi

  • actin cortical patch assembly Source: SGD
  • actin filament organization Source: SGD
  • endocytosis Source: SGD
  • establishment of protein localization to plasma membrane Source: SGD
Complete GO annotation...

Enzyme and pathway databases

BioCyciYEAST:G3O-32140-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Epsin-4
Gene namesi
Name:ENT4
Ordered Locus Names:YLL038C
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome XII

Organism-specific databases

EuPathDBiFungiDB:YLL038C.
SGDiS000003961. ENT4.

Subcellular locationi

GO - Cellular componenti

  • actin cortical patch Source: SGD
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 247247Epsin-4PRO_0000074527Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei195 – 1951PhosphoserineCombined sources

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiQ07872.
TopDownProteomicsiQ07872.

PTM databases

iPTMnetiQ07872.

Interactioni

GO - Molecular functioni

  • clathrin binding Source: SGD

Protein-protein interaction databases

BioGridi31216. 50 interactions.
DIPiDIP-2685N.
IntActiQ07872. 5 interactions.
MINTiMINT-1578275.

Structurei

3D structure databases

ProteinModelPortaliQ07872.
SMRiQ07872. Positions 13-146.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini7 – 146140ENTHPROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 1 ENTH (epsin N-terminal homology) domain.PROSITE-ProRule annotation

Phylogenomic databases

HOGENOMiHOG000112378.
InParanoidiQ07872.
OMAiIQFRSSI.
OrthoDBiEOG092C4V1P.

Family and domain databases

Gene3Di1.25.40.90. 1 hit.
InterProiIPR013809. ENTH.
IPR008942. ENTH_VHS.
[Graphical view]
PfamiPF01417. ENTH. 1 hit.
[Graphical view]
SMARTiSM00273. ENTH. 1 hit.
[Graphical view]
SUPFAMiSSF48464. SSF48464. 1 hit.
PROSITEiPS50942. ENTH. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q07872-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPLLDTFKSF IQSPTESKVK QATNEDETSG ATGTLMNEIS ILTYSPKTVR
60 70 80 90 100
EIIQVIRKRL LLGQNRRNSH RNCIQVMKTL TLVSYLMNNG SNEFIKWLKG
110 120 130 140 150
NMILIEILED FQVQDPRDER KAEDIQKLSR NVLGLLQDDG LLEKQRKDVI
160 170 180 190 200
QFRSSISTPG RKSTDNSHLK LEEMRSELTR QSLEKKAKPP TTSTSLDFQR
210 220 230 240
QRTRNTHEYA RFSLDPLAEE DSEDTPGVAG GISKLSFRPK SSNNPFR
Length:247
Mass (Da):28,271
Last modified:November 1, 1996 - v1
Checksum:iF5C95AA2402918D0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z73143 Genomic DNA. Translation: CAA97488.1.
AY558191 Genomic DNA. Translation: AAS56517.1.
BK006945 Genomic DNA. Translation: DAA09284.1.
PIRiS64789.
RefSeqiNP_013062.1. NM_001181858.1.

Genome annotation databases

EnsemblFungiiYLL038C; YLL038C; YLL038C.
GeneIDi850621.
KEGGisce:YLL038C.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z73143 Genomic DNA. Translation: CAA97488.1.
AY558191 Genomic DNA. Translation: AAS56517.1.
BK006945 Genomic DNA. Translation: DAA09284.1.
PIRiS64789.
RefSeqiNP_013062.1. NM_001181858.1.

3D structure databases

ProteinModelPortaliQ07872.
SMRiQ07872. Positions 13-146.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi31216. 50 interactions.
DIPiDIP-2685N.
IntActiQ07872. 5 interactions.
MINTiMINT-1578275.

PTM databases

iPTMnetiQ07872.

Proteomic databases

MaxQBiQ07872.
TopDownProteomicsiQ07872.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYLL038C; YLL038C; YLL038C.
GeneIDi850621.
KEGGisce:YLL038C.

Organism-specific databases

EuPathDBiFungiDB:YLL038C.
SGDiS000003961. ENT4.

Phylogenomic databases

HOGENOMiHOG000112378.
InParanoidiQ07872.
OMAiIQFRSSI.
OrthoDBiEOG092C4V1P.

Enzyme and pathway databases

BioCyciYEAST:G3O-32140-MONOMER.

Miscellaneous databases

PROiQ07872.

Family and domain databases

Gene3Di1.25.40.90. 1 hit.
InterProiIPR013809. ENTH.
IPR008942. ENTH_VHS.
[Graphical view]
PfamiPF01417. ENTH. 1 hit.
[Graphical view]
SMARTiSM00273. ENTH. 1 hit.
[Graphical view]
SUPFAMiSSF48464. SSF48464. 1 hit.
PROSITEiPS50942. ENTH. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiENT4_YEAST
AccessioniPrimary (citable) accession number: Q07872
Secondary accession number(s): D6VXW8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 26, 2005
Last sequence update: November 1, 1996
Last modified: September 7, 2016
This is version 108 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Miscellaneous

Present with 1960 molecules/cell in log phase SD medium.1 Publication

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome XII
    Yeast (Saccharomyces cerevisiae) chromosome XII: entries and gene names

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.