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Q07798

- SPO75_YEAST

UniProt

Q07798 - SPO75_YEAST

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Protein
Sporulation-specific protein 75
Gene
SPO75, YLL005C, L1361
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 3 out of 5 - Experimental evidence at protein leveli

Functioni

Acts as an osmosensitive calcium-permeable cation channel By similarity. Required for spore wall assembly and ascus formation.2 Publications

GO - Biological processi

  1. ascospore formation Source: SGD
  2. ascospore wall assembly Source: SGD
Complete GO annotation...

Keywords - Molecular functioni

Ion channel

Keywords - Biological processi

Ion transport, Sporulation, Transport

Keywords - Ligandi

Calcium

Enzyme and pathway databases

BioCyciYEAST:G3O-32110-MONOMER.

Protein family/group databases

TCDBi1.A.17.5.7. the calcium-dependent chloride channel (ca-clc) family.

Names & Taxonomyi

Protein namesi
Recommended name:
Sporulation-specific protein 75
Gene namesi
Name:SPO75
Ordered Locus Names:YLL005C
ORF Names:L1361
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
ProteomesiUP000002311: Chromosome XII

Organism-specific databases

CYGDiYLL005c.
SGDiS000003928. SPO75.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 3434Extracellular Reviewed prediction
Add
BLAST
Transmembranei35 – 5521Helical; Reviewed prediction
Add
BLAST
Topological domaini56 – 12772Cytoplasmic Reviewed prediction
Add
BLAST
Transmembranei128 – 14821Helical; Reviewed prediction
Add
BLAST
Topological domaini149 – 18739Extracellular Reviewed prediction
Add
BLAST
Transmembranei188 – 20821Helical; Reviewed prediction
Add
BLAST
Topological domaini209 – 481273Cytoplasmic Reviewed prediction
Add
BLAST
Transmembranei482 – 50221Helical; Reviewed prediction
Add
BLAST
Topological domaini503 – 52725Extracellular Reviewed prediction
Add
BLAST
Transmembranei528 – 54821Helical; Reviewed prediction
Add
BLAST
Topological domaini549 – 56921Cytoplasmic Reviewed prediction
Add
BLAST
Transmembranei570 – 59021Helical; Reviewed prediction
Add
BLAST
Topological domaini591 – 61121Extracellular Reviewed prediction
Add
BLAST
Transmembranei612 – 63221Helical; Reviewed prediction
Add
BLAST
Topological domaini633 – 66028Cytoplasmic Reviewed prediction
Add
BLAST
Transmembranei661 – 68323Helical; Reviewed prediction
Add
BLAST
Topological domaini684 – 6929Extracellular Reviewed prediction
Transmembranei693 – 71321Helical; Reviewed prediction
Add
BLAST
Topological domaini714 – 73017Cytoplasmic Reviewed prediction
Add
BLAST
Transmembranei731 – 75121Helical; Reviewed prediction
Add
BLAST
Topological domaini752 – 7532Extracellular Reviewed prediction
Transmembranei754 – 77421Helical; Reviewed prediction
Add
BLAST
Topological domaini775 – 86894Cytoplasmic Reviewed prediction
Add
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 868868Sporulation-specific protein 75
PRO_0000072143Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi2 – 21N-linked (GlcNAc...) Reviewed prediction
Glycosylationi184 – 1841N-linked (GlcNAc...) Reviewed prediction
Glycosylationi503 – 5031N-linked (GlcNAc...) Reviewed prediction

Keywords - PTMi

Glycoprotein

Expressioni

Gene expression databases

GenevestigatoriQ07798.

Interactioni

Protein-protein interaction databases

BioGridi31246. 13 interactions.
DIPiDIP-8843N.
IntActiQ07798. 3 interactions.
MINTiMINT-2782453.
STRINGi4932.YLL005C.

Structurei

3D structure databases

ProteinModelPortaliQ07798.

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG5594.
GeneTreeiENSGT00530000068232.
HOGENOMiHOG000141747.
OMAiENISETH.
OrthoDBiEOG71ZP92.

Family and domain databases

InterProiIPR003864. DUF221.
[Graphical view]
PfamiPF02714. DUF221. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q07798-1 [UniParc]FASTAAdd to Basket

« Hide

MNATKELTFN LLNKFQDKER FGSAQRHAGI SLKGFISGIL FSFLYFLFQL    50
SLFIILRSRF KTIYQANVVL KIHPGSKVCF AKKKIKNYWS LFAFLKQLPG 100
RMLDPMEKFE RNERYGLDNY LFLRFLKLLI FFFAVLSIIN IPILIPIHYF 150
SRDILKENEG ERYEQSFRTT SKLDKWTMSN LSPNSSNTLI CHLFLSIFVV 200
LWFHFILSSE LRFVNRLGYS VLTKSKYQNI LYLEGFSSKL VTQSISLETF 250
FQPLHSDCFG VTHFIPKNLK KVHKLEIKLN KLQKSKEQII FEIILEKYFR 300
RVSIHRHLIA NHKRFFFSKL KNHLLFQYKK LVFLTQFRIS YYCTKIRLRW 350
KKSSIFPLYY PKLYVNTETI LERKYRILDK IIRKEKLIKF QVNSLKATSE 400
TKQALPDDLS SGTDIYMDKM FITFKSTLLS NVIGELLSYR LPTQNLKVII 450
GPNVNDIIWR NILDSSPLWK SAKYFSANIL RIFVIIGWIL PVAFLGLISQ 500
IPNISSLIPF TKIIHFQSPF IREVAKNLIP IVTLIIIIEI VPYFFRWLSY 550
LRGLKTGAQI EADVQNWYFV FVFIHLFVVV TISSGFSIII ERLLNNPVSI 600
PALLANDLPK CANFFCSFVL IRGMAYAGGN LLRIKELLFE LFYYKWKRST 650
PHAQFKRLKT SLFFQLGSIY PIFSVLGCIG IIYSVVAPII LLLCCISFSM 700
VFFSFSYLFK YQYNKENYSE TFGKLYIQAL MQLYAGIYFM EFCLLGLFTL 750
FDQYTLSTIM LVVFALTVIT HSKISKQIKS KPQRIPTLEY LSNLTEERKD 800
QFCQESYTFH DIFSICRNSD EIWLPRDKLG ISEEEQSFLE KSYHLKFDLN 850
MYSMNLFGDC HLENSHLH 868
Length:868
Mass (Da):102,170
Last modified:November 1, 1996 - v1
Checksum:i10E4B5B8C7580653
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X91488 Genomic DNA. Translation: CAA62764.1.
Z73110 Genomic DNA. Translation: CAA97448.1.
BK006945 Genomic DNA. Translation: DAA09314.1.
PIRiS64747.
RefSeqiNP_013096.1. NM_001181825.1.

Genome annotation databases

EnsemblFungiiYLL005C; YLL005C; YLL005C.
GeneIDi850655.
KEGGisce:YLL005C.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X91488 Genomic DNA. Translation: CAA62764.1 .
Z73110 Genomic DNA. Translation: CAA97448.1 .
BK006945 Genomic DNA. Translation: DAA09314.1 .
PIRi S64747.
RefSeqi NP_013096.1. NM_001181825.1.

3D structure databases

ProteinModelPortali Q07798.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 31246. 13 interactions.
DIPi DIP-8843N.
IntActi Q07798. 3 interactions.
MINTi MINT-2782453.
STRINGi 4932.YLL005C.

Protein family/group databases

TCDBi 1.A.17.5.7. the calcium-dependent chloride channel (ca-clc) family.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblFungii YLL005C ; YLL005C ; YLL005C .
GeneIDi 850655.
KEGGi sce:YLL005C.

Organism-specific databases

CYGDi YLL005c.
SGDi S000003928. SPO75.

Phylogenomic databases

eggNOGi COG5594.
GeneTreei ENSGT00530000068232.
HOGENOMi HOG000141747.
OMAi ENISETH.
OrthoDBi EOG71ZP92.

Enzyme and pathway databases

BioCyci YEAST:G3O-32110-MONOMER.

Miscellaneous databases

NextBioi 966614.

Gene expression databases

Genevestigatori Q07798.

Family and domain databases

InterProi IPR003864. DUF221.
[Graphical view ]
Pfami PF02714. DUF221. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Sequence analysis of the CEN12 region of Saccharomyces cerevisiae on a 43.7 kb fragment of chromosome XII including an open reading frame homologous to the human cystic fibrosis transmembrane conductance regulator protein CFTR."
    Miosga T., Zimmermann F.K.
    Yeast 12:693-708(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Cited for: GENOME REANNOTATION.
    Strain: ATCC 204508 / S288c.
  3. "The nucleotide sequence of Saccharomyces cerevisiae chromosome XII."
    Johnston M., Hillier L.W., Riles L., Albermann K., Andre B., Ansorge W., Benes V., Brueckner M., Delius H., Dubois E., Duesterhoeft A., Entian K.-D., Floeth M., Goffeau A., Hebling U., Heumann K., Heuss-Neitzel D., Hilbert H.
    , Hilger F., Kleine K., Koetter P., Louis E.J., Messenguy F., Mewes H.-W., Miosga T., Moestl D., Mueller-Auer S., Nentwich U., Obermaier B., Piravandi E., Pohl T.M., Portetelle D., Purnelle B., Rechmann S., Rieger M., Rinke M., Rose M., Scharfe M., Scherens B., Scholler P., Schwager C., Schwarz S., Underwood A.P., Urrestarazu L.A., Vandenbol M., Verhasselt P., Vierendeels F., Voet M., Volckaert G., Voss H., Wambutt R., Wedler E., Wedler H., Zimmermann F.K., Zollner A., Hani J., Hoheisel J.D.
    Nature 387:87-90(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  4. Cited for: FUNCTION.
  5. "Morphogenetic pathway of spore wall assembly in Saccharomyces cerevisiae."
    Coluccio A., Bogengruber E., Conrad M.N., Dresser M.E., Briza P., Neiman A.M.
    Eukaryot. Cell 3:1464-1475(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION.
  6. "A global topology map of the Saccharomyces cerevisiae membrane proteome."
    Kim H., Melen K., Oesterberg M., von Heijne G.
    Proc. Natl. Acad. Sci. U.S.A. 103:11142-11147(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: TOPOLOGY [LARGE SCALE ANALYSIS].
    Strain: ATCC 208353 / W303-1A.

Entry informationi

Entry nameiSPO75_YEAST
AccessioniPrimary (citable) accession number: Q07798
Secondary accession number(s): D6VXZ8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 16, 2005
Last sequence update: November 1, 1996
Last modified: July 9, 2014
This is version 89 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome XII
    Yeast (Saccharomyces cerevisiae) chromosome XII: entries and gene names

External Data

Dasty 3

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