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Protein

Sporulation-specific protein 75

Gene

SPO75

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Acts as an osmosensitive calcium-permeable cation channel (By similarity). Required for spore wall assembly and ascus formation.By similarity2 Publications

GO - Biological processi

  • ascospore formation Source: SGD
  • ascospore wall assembly Source: SGD
  • ion transport Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Ion channel

Keywords - Biological processi

Ion transport, Sporulation, Transport

Keywords - Ligandi

Calcium

Enzyme and pathway databases

BioCyciYEAST:G3O-32110-MONOMER.

Protein family/group databases

TCDBi1.A.17.5.7. the calcium-dependent chloride channel (ca-clc) family.

Names & Taxonomyi

Protein namesi
Recommended name:
Sporulation-specific protein 75
Gene namesi
Name:SPO75
Ordered Locus Names:YLL005C
ORF Names:L1361
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome XII

Organism-specific databases

EuPathDBiFungiDB:YLL005C.
SGDiS000003928. SPO75.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 34ExtracellularSequence analysisAdd BLAST34
Transmembranei35 – 55HelicalSequence analysisAdd BLAST21
Topological domaini56 – 127CytoplasmicSequence analysisAdd BLAST72
Transmembranei128 – 148HelicalSequence analysisAdd BLAST21
Topological domaini149 – 187ExtracellularSequence analysisAdd BLAST39
Transmembranei188 – 208HelicalSequence analysisAdd BLAST21
Topological domaini209 – 481CytoplasmicSequence analysisAdd BLAST273
Transmembranei482 – 502HelicalSequence analysisAdd BLAST21
Topological domaini503 – 527ExtracellularSequence analysisAdd BLAST25
Transmembranei528 – 548HelicalSequence analysisAdd BLAST21
Topological domaini549 – 569CytoplasmicSequence analysisAdd BLAST21
Transmembranei570 – 590HelicalSequence analysisAdd BLAST21
Topological domaini591 – 611ExtracellularSequence analysisAdd BLAST21
Transmembranei612 – 632HelicalSequence analysisAdd BLAST21
Topological domaini633 – 660CytoplasmicSequence analysisAdd BLAST28
Transmembranei661 – 683HelicalSequence analysisAdd BLAST23
Topological domaini684 – 692ExtracellularSequence analysis9
Transmembranei693 – 713HelicalSequence analysisAdd BLAST21
Topological domaini714 – 730CytoplasmicSequence analysisAdd BLAST17
Transmembranei731 – 751HelicalSequence analysisAdd BLAST21
Topological domaini752 – 753ExtracellularSequence analysis2
Transmembranei754 – 774HelicalSequence analysisAdd BLAST21
Topological domaini775 – 868CytoplasmicSequence analysisAdd BLAST94

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000721431 – 868Sporulation-specific protein 75Add BLAST868

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi2N-linked (GlcNAc...)Sequence analysis1
Glycosylationi184N-linked (GlcNAc...)Sequence analysis1
Glycosylationi503N-linked (GlcNAc...)Sequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

PRIDEiQ07798.

Interactioni

Protein-protein interaction databases

BioGridi31246. 13 interactors.
DIPiDIP-8843N.
IntActiQ07798. 3 interactors.
MINTiMINT-2782453.

Structurei

3D structure databases

ProteinModelPortaliQ07798.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

GeneTreeiENSGT00530000068232.
HOGENOMiHOG000141747.
InParanoidiQ07798.
OMAiLIRGMAY.
OrthoDBiEOG092C23E4.

Family and domain databases

InterProiIPR032880. Csc1_N.
IPR003864. RSN1_7TM.
[Graphical view]
PfamiPF02714. RSN1_7TM. 1 hit.
PF13967. RSN1_TM. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q07798-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNATKELTFN LLNKFQDKER FGSAQRHAGI SLKGFISGIL FSFLYFLFQL
60 70 80 90 100
SLFIILRSRF KTIYQANVVL KIHPGSKVCF AKKKIKNYWS LFAFLKQLPG
110 120 130 140 150
RMLDPMEKFE RNERYGLDNY LFLRFLKLLI FFFAVLSIIN IPILIPIHYF
160 170 180 190 200
SRDILKENEG ERYEQSFRTT SKLDKWTMSN LSPNSSNTLI CHLFLSIFVV
210 220 230 240 250
LWFHFILSSE LRFVNRLGYS VLTKSKYQNI LYLEGFSSKL VTQSISLETF
260 270 280 290 300
FQPLHSDCFG VTHFIPKNLK KVHKLEIKLN KLQKSKEQII FEIILEKYFR
310 320 330 340 350
RVSIHRHLIA NHKRFFFSKL KNHLLFQYKK LVFLTQFRIS YYCTKIRLRW
360 370 380 390 400
KKSSIFPLYY PKLYVNTETI LERKYRILDK IIRKEKLIKF QVNSLKATSE
410 420 430 440 450
TKQALPDDLS SGTDIYMDKM FITFKSTLLS NVIGELLSYR LPTQNLKVII
460 470 480 490 500
GPNVNDIIWR NILDSSPLWK SAKYFSANIL RIFVIIGWIL PVAFLGLISQ
510 520 530 540 550
IPNISSLIPF TKIIHFQSPF IREVAKNLIP IVTLIIIIEI VPYFFRWLSY
560 570 580 590 600
LRGLKTGAQI EADVQNWYFV FVFIHLFVVV TISSGFSIII ERLLNNPVSI
610 620 630 640 650
PALLANDLPK CANFFCSFVL IRGMAYAGGN LLRIKELLFE LFYYKWKRST
660 670 680 690 700
PHAQFKRLKT SLFFQLGSIY PIFSVLGCIG IIYSVVAPII LLLCCISFSM
710 720 730 740 750
VFFSFSYLFK YQYNKENYSE TFGKLYIQAL MQLYAGIYFM EFCLLGLFTL
760 770 780 790 800
FDQYTLSTIM LVVFALTVIT HSKISKQIKS KPQRIPTLEY LSNLTEERKD
810 820 830 840 850
QFCQESYTFH DIFSICRNSD EIWLPRDKLG ISEEEQSFLE KSYHLKFDLN
860
MYSMNLFGDC HLENSHLH
Length:868
Mass (Da):102,170
Last modified:November 1, 1996 - v1
Checksum:i10E4B5B8C7580653
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X91488 Genomic DNA. Translation: CAA62764.1.
Z73110 Genomic DNA. Translation: CAA97448.1.
BK006945 Genomic DNA. Translation: DAA09314.1.
PIRiS64747.
RefSeqiNP_013096.1. NM_001181825.1.

Genome annotation databases

EnsemblFungiiYLL005C; YLL005C; YLL005C.
GeneIDi850655.
KEGGisce:YLL005C.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X91488 Genomic DNA. Translation: CAA62764.1.
Z73110 Genomic DNA. Translation: CAA97448.1.
BK006945 Genomic DNA. Translation: DAA09314.1.
PIRiS64747.
RefSeqiNP_013096.1. NM_001181825.1.

3D structure databases

ProteinModelPortaliQ07798.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi31246. 13 interactors.
DIPiDIP-8843N.
IntActiQ07798. 3 interactors.
MINTiMINT-2782453.

Protein family/group databases

TCDBi1.A.17.5.7. the calcium-dependent chloride channel (ca-clc) family.

Proteomic databases

PRIDEiQ07798.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYLL005C; YLL005C; YLL005C.
GeneIDi850655.
KEGGisce:YLL005C.

Organism-specific databases

EuPathDBiFungiDB:YLL005C.
SGDiS000003928. SPO75.

Phylogenomic databases

GeneTreeiENSGT00530000068232.
HOGENOMiHOG000141747.
InParanoidiQ07798.
OMAiLIRGMAY.
OrthoDBiEOG092C23E4.

Enzyme and pathway databases

BioCyciYEAST:G3O-32110-MONOMER.

Miscellaneous databases

PROiQ07798.

Family and domain databases

InterProiIPR032880. Csc1_N.
IPR003864. RSN1_7TM.
[Graphical view]
PfamiPF02714. RSN1_7TM. 1 hit.
PF13967. RSN1_TM. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiSPO75_YEAST
AccessioniPrimary (citable) accession number: Q07798
Secondary accession number(s): D6VXZ8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 16, 2005
Last sequence update: November 1, 1996
Last modified: November 2, 2016
This is version 105 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome XII
    Yeast (Saccharomyces cerevisiae) chromosome XII: entries and gene names

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.