Sporulation-specific protein 75 - Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

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Q07798 (SPO75_YEAST) Reviewed, UniProtKB/Swiss-Prot

Last modified April 3, 2013. Version 79. History...

Clusters with 100%, 90%, 50% identity |

Documents (3) |

Third-party data

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Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents Customize order

Names and origin

Protein names

Recommended name:
Sporulation-specific protein 75

Gene names

Name:	SPO75
Ordered Locus Names:	YLL005C
ORF Names:	L1361

Organism

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]

Taxonomic identifier

559292 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces ›

Protein attributes

Sequence length	868 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	Required for spore wall assembly and ascus formation. Ref.4 Ref.5
Subcellular location	Membrane; Multi-pass membrane protein.
Sequence similarities	Belongs to the SPO75/TMEM63 family.

Ontologies

Keywords
Biological process	Sporulation
Cellular component	Membrane
Domain	Transmembrane Transmembrane helix
PTM	Glycoprotein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	ascospore wall assembly Inferred from mutant phenotype Ref.5. Source: SGD
Cellular_component	integral to membrane Inferred from sequence model PubMed 12192589. Source: SGD
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Molecule processing

Chain

1 – 868

868

Sporulation-specific protein 75

PRO_0000072143

Regions

Topological domain

1 – 34

Extracellular Potential

Transmembrane

35 – 55

Helical; Potential

Topological domain

56 – 127

Cytoplasmic Potential

Transmembrane

128 – 148

Helical; Potential

Topological domain

149 – 187

Extracellular Potential

Transmembrane

188 – 208

Helical; Potential

Topological domain

209 – 481

273

Cytoplasmic Potential

Transmembrane

482 – 502

Helical; Potential

Topological domain

503 – 527

Extracellular Potential

Transmembrane

528 – 548

Helical; Potential

Topological domain

549 – 569

Cytoplasmic Potential

Transmembrane

570 – 590

Helical; Potential

Topological domain

591 – 611

Extracellular Potential

Transmembrane

612 – 632

Helical; Potential

Topological domain

633 – 660

Cytoplasmic Potential

Transmembrane

661 – 683

Helical; Potential

Topological domain

684 – 692

Extracellular Potential

Transmembrane

693 – 713

Helical; Potential

Topological domain

714 – 730

Cytoplasmic Potential

Transmembrane

731 – 751

Helical; Potential

Topological domain

752 – 753

Extracellular Potential

Transmembrane

754 – 774

Helical; Potential

Topological domain

775 – 868

Cytoplasmic Potential

Amino acid modifications

Glycosylation

N-linked (GlcNAc...) Potential

Glycosylation

184

N-linked (GlcNAc...) Potential

Glycosylation

503

N-linked (GlcNAc...) Potential

Sequences

Sequence

Length

Mass (Da)

Tools

Q07798 [UniParc].

Last modified November 1, 1996. Version 1.
Checksum: 10E4B5B8C7580653
Show »

FASTA

868

102,170

        10         20         30         40         50         60 
MNATKELTFN LLNKFQDKER FGSAQRHAGI SLKGFISGIL FSFLYFLFQL SLFIILRSRF 

        70         80         90        100        110        120 
KTIYQANVVL KIHPGSKVCF AKKKIKNYWS LFAFLKQLPG RMLDPMEKFE RNERYGLDNY 

       130        140        150        160        170        180 
LFLRFLKLLI FFFAVLSIIN IPILIPIHYF SRDILKENEG ERYEQSFRTT SKLDKWTMSN 

       190        200        210        220        230        240 
LSPNSSNTLI CHLFLSIFVV LWFHFILSSE LRFVNRLGYS VLTKSKYQNI LYLEGFSSKL 

       250        260        270        280        290        300 
VTQSISLETF FQPLHSDCFG VTHFIPKNLK KVHKLEIKLN KLQKSKEQII FEIILEKYFR 

       310        320        330        340        350        360 
RVSIHRHLIA NHKRFFFSKL KNHLLFQYKK LVFLTQFRIS YYCTKIRLRW KKSSIFPLYY 

       370        380        390        400        410        420 
PKLYVNTETI LERKYRILDK IIRKEKLIKF QVNSLKATSE TKQALPDDLS SGTDIYMDKM 

       430        440        450        460        470        480 
FITFKSTLLS NVIGELLSYR LPTQNLKVII GPNVNDIIWR NILDSSPLWK SAKYFSANIL 

       490        500        510        520        530        540 
RIFVIIGWIL PVAFLGLISQ IPNISSLIPF TKIIHFQSPF IREVAKNLIP IVTLIIIIEI 

       550        560        570        580        590        600 
VPYFFRWLSY LRGLKTGAQI EADVQNWYFV FVFIHLFVVV TISSGFSIII ERLLNNPVSI 

       610        620        630        640        650        660 
PALLANDLPK CANFFCSFVL IRGMAYAGGN LLRIKELLFE LFYYKWKRST PHAQFKRLKT 

       670        680        690        700        710        720 
SLFFQLGSIY PIFSVLGCIG IIYSVVAPII LLLCCISFSM VFFSFSYLFK YQYNKENYSE 

       730        740        750        760        770        780 
TFGKLYIQAL MQLYAGIYFM EFCLLGLFTL FDQYTLSTIM LVVFALTVIT HSKISKQIKS 

       790        800        810        820        830        840 
KPQRIPTLEY LSNLTEERKD QFCQESYTFH DIFSICRNSD EIWLPRDKLG ISEEEQSFLE 

       850        860 
KSYHLKFDLN MYSMNLFGDC HLENSHLH

« Hide

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Sequence analysis of the CEN12 region of Saccharomyces cerevisiae on a 43.7 kb fragment of chromosome XII including an open reading frame homologous to the human cystic fibrosis transmembrane conductance regulator protein CFTR." Miosga T., Zimmermann F.K. Yeast 12:693-708(1996) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]	Saccharomyces Genome Database Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases Cited for: GENOME REANNOTATION. Strain: ATCC 204508 / S288c.
[3]	"The nucleotide sequence of Saccharomyces cerevisiae chromosome XII." Johnston M., Hillier L.W., Riles L., Albermann K., Andre B., Ansorge W., Benes V., Brueckner M., Delius H., Dubois E., Duesterhoeft A., Entian K.-D., Floeth M., Goffeau A., Hebling U., Heumann K., Heuss-Neitzel D., Hilbert H. Hoheisel J.D. Nature 387:87-90(1997) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 204511 / S288c / AB972.
[4]	"A screen for genes required for meiosis and spore formation based on whole-genome expression." Rabitsch K.P., Toth A., Galova M., Schleiffer A., Schaffner G., Aigner E., Rupp C., Penkner A.M., Moreno-Borchart A.C., Primig M., Esposito R.E., Klein F., Knop M., Nasmyth K. Curr. Biol. 11:1001-1009(2001) [PubMed] [Europe PMC] [Abstract] Cited for: FUNCTION.
[5]	"Morphogenetic pathway of spore wall assembly in Saccharomyces cerevisiae." Coluccio A., Bogengruber E., Conrad M.N., Dresser M.E., Briza P., Neiman A.M. Eukaryot. Cell 3:1464-1475(2004) [PubMed] [Europe PMC] [Abstract] Cited for: FUNCTION.
[6]	"A global topology map of the Saccharomyces cerevisiae membrane proteome." Kim H., Melen K., Oesterberg M., von Heijne G. Proc. Natl. Acad. Sci. U.S.A. 103:11142-11147(2006) [PubMed] [Europe PMC] [Abstract] Cited for: TOPOLOGY [LARGE SCALE ANALYSIS]. Strain: ATCC 208353 / W303-1A.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	X91488 Genomic DNA. Translation: CAA62764.1. Z73110 Genomic DNA. Translation: CAA97448.1. BK006945 Genomic DNA. Translation: DAA09314.1.
PIR	S64747.
RefSeq	NP_013096.1. NM_001181825.1.
3D structure databases
ProteinModelPortal	Q07798.
ModBase	Search...
Protein-protein interaction databases
DIP	DIP-8843N.
MINT	MINT-2782453.
STRING	4932.YLL005C.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblFungi	YLL005C; YLL005C; YLL005C.
GeneID	850655.
KEGG	sce:YLL005C.
Organism-specific databases
CYGD	YLL005c.
SGD	S000003928. SPO75.
Phylogenomic databases
eggNOG	COG5594.
GeneTree	ENSGT00530000068232.
HOGENOM	HOG000141747.
OMA	ENISETH.
OrthoDB	EOG4QVGM2.
Gene expression databases
Genevestigator	Q07798.
GermOnline	YLL005C. Saccharomyces cerevisiae.
Family and domain databases
InterPro	IPR003864. DUF221. [Graphical view]
Pfam	PF02714. DUF221. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	966614.

Entry information

Entry name

SPO75_YEAST

Accession

Primary (citable) accession number: Q07798
Secondary accession number(s): D6VXZ8

Entry history

Integrated into UniProtKB/Swiss-Prot:	August 16, 2005
Last sequence update:	November 1, 1996
Last modified:	April 3, 2013
This is version 79 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program

Relevant documents

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD

Yeast chromosome XII

Yeast (Saccharomyces cerevisiae) chromosome XII: entries and gene names

SIMILARITY comments

Index of protein domains and families

Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents

Preferred order of sections

Names and origin

Protein attributes

General annotation (Comments)

Ontologies

Sequence annotation (Features)

Molecule processing

Regions

Amino acid modifications

Sequences

References

Cross-references

Sequence databases

3D structure databases

Protein-protein interaction databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Gene expression databases

Family and domain databases

Other

Entry information

Relevant documents