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Q07798

- SPO75_YEAST

UniProt

Q07798 - SPO75_YEAST

Protein

Sporulation-specific protein 75

Gene

SPO75

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 90 (01 Oct 2014)
      Sequence version 1 (01 Nov 1996)
      Previous versions | rss
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    Functioni

    Acts as an osmosensitive calcium-permeable cation channel By similarity. Required for spore wall assembly and ascus formation.By similarity2 Publications

    GO - Biological processi

    1. ascospore formation Source: SGD
    2. ascospore wall assembly Source: SGD
    3. ion transport Source: UniProtKB-KW

    Keywords - Molecular functioni

    Ion channel

    Keywords - Biological processi

    Ion transport, Sporulation, Transport

    Keywords - Ligandi

    Calcium

    Enzyme and pathway databases

    BioCyciYEAST:G3O-32110-MONOMER.

    Protein family/group databases

    TCDBi1.A.17.5.7. the calcium-dependent chloride channel (ca-clc) family.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Sporulation-specific protein 75
    Gene namesi
    Name:SPO75
    Ordered Locus Names:YLL005C
    ORF Names:L1361
    OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
    Taxonomic identifieri559292 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
    ProteomesiUP000002311: Chromosome XII

    Organism-specific databases

    CYGDiYLL005c.
    SGDiS000003928. SPO75.

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW

    Keywords - Cellular componenti

    Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 868868Sporulation-specific protein 75PRO_0000072143Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Glycosylationi2 – 21N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi184 – 1841N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi503 – 5031N-linked (GlcNAc...)Sequence Analysis

    Keywords - PTMi

    Glycoprotein

    Expressioni

    Gene expression databases

    GenevestigatoriQ07798.

    Interactioni

    Protein-protein interaction databases

    BioGridi31246. 13 interactions.
    DIPiDIP-8843N.
    IntActiQ07798. 3 interactions.
    MINTiMINT-2782453.
    STRINGi4932.YLL005C.

    Structurei

    3D structure databases

    ProteinModelPortaliQ07798.
    ModBaseiSearch...
    MobiDBiSearch...

    Topological domain

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Topological domaini1 – 3434ExtracellularSequence AnalysisAdd
    BLAST
    Topological domaini56 – 12772CytoplasmicSequence AnalysisAdd
    BLAST
    Topological domaini149 – 18739ExtracellularSequence AnalysisAdd
    BLAST
    Topological domaini209 – 481273CytoplasmicSequence AnalysisAdd
    BLAST
    Topological domaini503 – 52725ExtracellularSequence AnalysisAdd
    BLAST
    Topological domaini549 – 56921CytoplasmicSequence AnalysisAdd
    BLAST
    Topological domaini591 – 61121ExtracellularSequence AnalysisAdd
    BLAST
    Topological domaini633 – 66028CytoplasmicSequence AnalysisAdd
    BLAST
    Topological domaini684 – 6929ExtracellularSequence Analysis
    Topological domaini714 – 73017CytoplasmicSequence AnalysisAdd
    BLAST
    Topological domaini752 – 7532ExtracellularSequence Analysis
    Topological domaini775 – 86894CytoplasmicSequence AnalysisAdd
    BLAST

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei35 – 5521HelicalSequence AnalysisAdd
    BLAST
    Transmembranei128 – 14821HelicalSequence AnalysisAdd
    BLAST
    Transmembranei188 – 20821HelicalSequence AnalysisAdd
    BLAST
    Transmembranei482 – 50221HelicalSequence AnalysisAdd
    BLAST
    Transmembranei528 – 54821HelicalSequence AnalysisAdd
    BLAST
    Transmembranei570 – 59021HelicalSequence AnalysisAdd
    BLAST
    Transmembranei612 – 63221HelicalSequence AnalysisAdd
    BLAST
    Transmembranei661 – 68323HelicalSequence AnalysisAdd
    BLAST
    Transmembranei693 – 71321HelicalSequence AnalysisAdd
    BLAST
    Transmembranei731 – 75121HelicalSequence AnalysisAdd
    BLAST
    Transmembranei754 – 77421HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiCOG5594.
    GeneTreeiENSGT00530000068232.
    HOGENOMiHOG000141747.
    OMAiENISETH.
    OrthoDBiEOG71ZP92.

    Family and domain databases

    InterProiIPR003864. DUF221.
    [Graphical view]
    PfamiPF02714. DUF221. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q07798-1 [UniParc]FASTAAdd to Basket

    « Hide

    MNATKELTFN LLNKFQDKER FGSAQRHAGI SLKGFISGIL FSFLYFLFQL    50
    SLFIILRSRF KTIYQANVVL KIHPGSKVCF AKKKIKNYWS LFAFLKQLPG 100
    RMLDPMEKFE RNERYGLDNY LFLRFLKLLI FFFAVLSIIN IPILIPIHYF 150
    SRDILKENEG ERYEQSFRTT SKLDKWTMSN LSPNSSNTLI CHLFLSIFVV 200
    LWFHFILSSE LRFVNRLGYS VLTKSKYQNI LYLEGFSSKL VTQSISLETF 250
    FQPLHSDCFG VTHFIPKNLK KVHKLEIKLN KLQKSKEQII FEIILEKYFR 300
    RVSIHRHLIA NHKRFFFSKL KNHLLFQYKK LVFLTQFRIS YYCTKIRLRW 350
    KKSSIFPLYY PKLYVNTETI LERKYRILDK IIRKEKLIKF QVNSLKATSE 400
    TKQALPDDLS SGTDIYMDKM FITFKSTLLS NVIGELLSYR LPTQNLKVII 450
    GPNVNDIIWR NILDSSPLWK SAKYFSANIL RIFVIIGWIL PVAFLGLISQ 500
    IPNISSLIPF TKIIHFQSPF IREVAKNLIP IVTLIIIIEI VPYFFRWLSY 550
    LRGLKTGAQI EADVQNWYFV FVFIHLFVVV TISSGFSIII ERLLNNPVSI 600
    PALLANDLPK CANFFCSFVL IRGMAYAGGN LLRIKELLFE LFYYKWKRST 650
    PHAQFKRLKT SLFFQLGSIY PIFSVLGCIG IIYSVVAPII LLLCCISFSM 700
    VFFSFSYLFK YQYNKENYSE TFGKLYIQAL MQLYAGIYFM EFCLLGLFTL 750
    FDQYTLSTIM LVVFALTVIT HSKISKQIKS KPQRIPTLEY LSNLTEERKD 800
    QFCQESYTFH DIFSICRNSD EIWLPRDKLG ISEEEQSFLE KSYHLKFDLN 850
    MYSMNLFGDC HLENSHLH 868
    Length:868
    Mass (Da):102,170
    Last modified:November 1, 1996 - v1
    Checksum:i10E4B5B8C7580653
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X91488 Genomic DNA. Translation: CAA62764.1.
    Z73110 Genomic DNA. Translation: CAA97448.1.
    BK006945 Genomic DNA. Translation: DAA09314.1.
    PIRiS64747.
    RefSeqiNP_013096.1. NM_001181825.1.

    Genome annotation databases

    EnsemblFungiiYLL005C; YLL005C; YLL005C.
    GeneIDi850655.
    KEGGisce:YLL005C.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X91488 Genomic DNA. Translation: CAA62764.1 .
    Z73110 Genomic DNA. Translation: CAA97448.1 .
    BK006945 Genomic DNA. Translation: DAA09314.1 .
    PIRi S64747.
    RefSeqi NP_013096.1. NM_001181825.1.

    3D structure databases

    ProteinModelPortali Q07798.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 31246. 13 interactions.
    DIPi DIP-8843N.
    IntActi Q07798. 3 interactions.
    MINTi MINT-2782453.
    STRINGi 4932.YLL005C.

    Protein family/group databases

    TCDBi 1.A.17.5.7. the calcium-dependent chloride channel (ca-clc) family.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblFungii YLL005C ; YLL005C ; YLL005C .
    GeneIDi 850655.
    KEGGi sce:YLL005C.

    Organism-specific databases

    CYGDi YLL005c.
    SGDi S000003928. SPO75.

    Phylogenomic databases

    eggNOGi COG5594.
    GeneTreei ENSGT00530000068232.
    HOGENOMi HOG000141747.
    OMAi ENISETH.
    OrthoDBi EOG71ZP92.

    Enzyme and pathway databases

    BioCyci YEAST:G3O-32110-MONOMER.

    Miscellaneous databases

    NextBioi 966614.

    Gene expression databases

    Genevestigatori Q07798.

    Family and domain databases

    InterProi IPR003864. DUF221.
    [Graphical view ]
    Pfami PF02714. DUF221. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Sequence analysis of the CEN12 region of Saccharomyces cerevisiae on a 43.7 kb fragment of chromosome XII including an open reading frame homologous to the human cystic fibrosis transmembrane conductance regulator protein CFTR."
      Miosga T., Zimmermann F.K.
      Yeast 12:693-708(1996) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    2. Cited for: GENOME REANNOTATION.
      Strain: ATCC 204508 / S288c.
    3. "The nucleotide sequence of Saccharomyces cerevisiae chromosome XII."
      Johnston M., Hillier L.W., Riles L., Albermann K., Andre B., Ansorge W., Benes V., Brueckner M., Delius H., Dubois E., Duesterhoeft A., Entian K.-D., Floeth M., Goffeau A., Hebling U., Heumann K., Heuss-Neitzel D., Hilbert H.
      , Hilger F., Kleine K., Koetter P., Louis E.J., Messenguy F., Mewes H.-W., Miosga T., Moestl D., Mueller-Auer S., Nentwich U., Obermaier B., Piravandi E., Pohl T.M., Portetelle D., Purnelle B., Rechmann S., Rieger M., Rinke M., Rose M., Scharfe M., Scherens B., Scholler P., Schwager C., Schwarz S., Underwood A.P., Urrestarazu L.A., Vandenbol M., Verhasselt P., Vierendeels F., Voet M., Volckaert G., Voss H., Wambutt R., Wedler E., Wedler H., Zimmermann F.K., Zollner A., Hani J., Hoheisel J.D.
      Nature 387:87-90(1997) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 204508 / S288c.
    4. Cited for: FUNCTION.
    5. "Morphogenetic pathway of spore wall assembly in Saccharomyces cerevisiae."
      Coluccio A., Bogengruber E., Conrad M.N., Dresser M.E., Briza P., Neiman A.M.
      Eukaryot. Cell 3:1464-1475(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: FUNCTION.
    6. "A global topology map of the Saccharomyces cerevisiae membrane proteome."
      Kim H., Melen K., Oesterberg M., von Heijne G.
      Proc. Natl. Acad. Sci. U.S.A. 103:11142-11147(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: TOPOLOGY [LARGE SCALE ANALYSIS].
      Strain: ATCC 208353 / W303-1A.

    Entry informationi

    Entry nameiSPO75_YEAST
    AccessioniPrimary (citable) accession number: Q07798
    Secondary accession number(s): D6VXZ8
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: August 16, 2005
    Last sequence update: November 1, 1996
    Last modified: October 1, 2014
    This is version 90 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families
    2. Yeast
      Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
    3. Yeast chromosome XII
      Yeast (Saccharomyces cerevisiae) chromosome XII: entries and gene names

    External Data

    Dasty 3