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Protein

Sensor protein ChvG

Gene

chvG

Organism
Agrobacterium fabrum (strain C58 / ATCC 33970) (Agrobacterium tumefaciens (strain C58))
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Member of a two-component regulatory system ChvG/ChvI. Activates ChvI by phosphorylation (Potential).Curated

Catalytic activityi

ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.

GO - Molecular functioni

Keywordsi

Molecular functionKinase, Transferase
Biological processTwo-component regulatory system
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciAGRO:ATU0033-MONOMER.
BRENDAi2.7.13.3. 200.

Names & Taxonomyi

Protein namesi
Recommended name:
Sensor protein ChvG (EC:2.7.13.3)
Gene namesi
Name:chvG
Ordered Locus Names:Atu0033
ORF Names:AGR_C_52
OrganismiAgrobacterium fabrum (strain C58 / ATCC 33970) (Agrobacterium tumefaciens (strain C58))
Taxonomic identifieri176299 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeRhizobium/Agrobacterium groupAgrobacteriumAgrobacterium tumefaciens complex
Proteomesi
  • UP000000813 Componenti: Chromosome circular

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 47CytoplasmicSequence analysisAdd BLAST47
Transmembranei48 – 68HelicalSequence analysisAdd BLAST21
Topological domaini69 – 283PeriplasmicSequence analysisAdd BLAST215
Transmembranei284 – 304HelicalSequence analysisAdd BLAST21
Topological domaini305 – 596CytoplasmicSequence analysisAdd BLAST292

GO - Cellular componenti

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000747201 – 596Sensor protein ChvGAdd BLAST596

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei367PhosphohistidineBy similarity1

Keywords - PTMi

Phosphoprotein

Interactioni

Protein-protein interaction databases

STRINGi176299.Atu0033.

Structurei

3D structure databases

ProteinModelPortaliQ07737.
SMRiQ07737.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini301 – 356HAMPPROSITE-ProRule annotationAdd BLAST56
Domaini364 – 592Histidine kinasePROSITE-ProRule annotationAdd BLAST229

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105EB3. Bacteria.
COG0642. LUCA.
HOGENOMiHOG000226685.
KOiK14980.
OMAiVPIQRFR.

Family and domain databases

CDDicd06225. HAMP. 1 hit.
cd00082. HisKA. 1 hit.
Gene3Di3.30.565.10. 1 hit.
InterProiView protein in InterPro
IPR003660. HAMP_dom.
IPR003594. HATPase_C.
IPR005467. His_kinase_dom.
IPR003661. HisK_dim/P.
IPR025908. Sensor_TM1.
IPR004358. Sig_transdc_His_kin-like_C.
IPR025919. Stimulus_sens_dom.
PfamiView protein in Pfam
PF00672. HAMP. 1 hit.
PF02518. HATPase_c. 1 hit.
PF00512. HisKA. 1 hit.
PF13755. Sensor_TM1. 1 hit.
PF13756. Stimulus_sens_1. 1 hit.
PRINTSiPR00344. BCTRLSENSOR.
SMARTiView protein in SMART
SM00304. HAMP. 1 hit.
SM00387. HATPase_c. 1 hit.
SM00388. HisKA. 1 hit.
SUPFAMiSSF47384. SSF47384. 1 hit.
SSF55874. SSF55874. 1 hit.
PROSITEiView protein in PROSITE
PS50885. HAMP. 1 hit.
PS50109. HIS_KIN. 1 hit.

Sequencei

Sequence statusi: Complete.

Q07737-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLKKTPETVS DSDDAEERGS ERRHRIHPLT IIRRIFGNAV FSSLTRRILF
60 70 80 90 100
FNVAATVVLV GGILYLNQFR EGLIDARVES LLTQGEIIAG AVSASASVDT
110 120 130 140 150
NSITINPEKL LELQAGQSIT PAPNDEDLSF PINPERVAPV LRRLISPTRT
160 170 180 190 200
RARLFDADAN LLLDSRHLYS RGQVLRFDLP PVTPETQTWG DWFTSMFNRM
210 220 230 240 250
LQPSSLPQYK EAPGGDGSIY PEVMNALTGV RGAVVRVTEK GELIVSVAVP
260 270 280 290 300
VQRFRAVLGV LLLSTQAGDI DKIVHAERLA IMRVFGIATL VNIVLSLLLS
310 320 330 340 350
STIATPLRRL SAAAIRVRRG ARTREEIPDF SARQDEIGNL SIALREMTTA
360 370 380 390 400
LYDRIDAIES FAADVSHELK NPLTSLRSAV ETLPRAKTEE SKQRLTEIIF
410 420 430 440 450
HDVRRLDRLI SDISDASRLD AELARADASP LDLDVLMKGL VDISRQISTK
460 470 480 490 500
KKSVAIDYVA DRKAGAKTSF VVNGHDLRIG QIVTNLIENA RSFVSEESGR
510 520 530 540 550
ITVRLSRHKD RCIVQVEDNG PGIQAEDIDR IFERFYTDRP ASEGFGQNSG
560 570 580 590
LGLSISRQIA EAHGGSLRAE NVVDKYGVIS GARFTLSLPA AETHER
Length:596
Mass (Da):65,722
Last modified:March 27, 2002 - v2
Checksum:i8931990E49736C4B
GO

Sequence cautioni

The sequence AAA03552 differs from that shown. Reason: Frameshift at positions 18, 152, 183, 216, 234 and 567.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti94A → R in AAA03552 (PubMed:8407839).Curated1
Sequence conflicti236R → P (PubMed:8407839).Curated1
Sequence conflicti314 – 318AIRVR → RSGA in AAA03552 (PubMed:8407839).Curated5

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L18860 Unassigned DNA. Translation: AAA03552.1. Frameshift.
AE007869 Genomic DNA. Translation: AAK85857.1.
PIRiA49902.
AB2581.
H97362.
RefSeqiNP_353072.1. NC_003062.2.
WP_006311105.1. NC_003062.2.

Genome annotation databases

EnsemblBacteriaiAAK85857; AAK85857; Atu0033.
GeneIDi1132071.
KEGGiatu:Atu0033.
PATRICifig|176299.10.peg.33.

Similar proteinsi

Entry informationi

Entry nameiCHVG_AGRFC
AccessioniPrimary (citable) accession number: Q07737
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: March 27, 2002
Last modified: September 27, 2017
This is version 126 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome