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Protein

Sensor protein ChvG

Gene

chvG

Organism
Agrobacterium fabrum (strain C58 / ATCC 33970) (Agrobacterium tumefaciens (strain C58))
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Member of a two-component regulatory system ChvG/ChvI. Activates ChvI by phosphorylation (Potential).Curated

Catalytic activityi

ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Biological processi

Two-component regulatory system

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciAGRO:ATU0033-MONOMER.
BRENDAi2.7.13.3. 200.

Names & Taxonomyi

Protein namesi
Recommended name:
Sensor protein ChvG (EC:2.7.13.3)
Gene namesi
Name:chvG
Ordered Locus Names:Atu0033
ORF Names:AGR_C_52
OrganismiAgrobacterium fabrum (strain C58 / ATCC 33970) (Agrobacterium tumefaciens (strain C58))
Taxonomic identifieri176299 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeRhizobium/Agrobacterium groupAgrobacteriumAgrobacterium tumefaciens complex
Proteomesi
  • UP000000813 Componenti: Chromosome circular

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 4747CytoplasmicSequence analysisAdd
BLAST
Transmembranei48 – 6821HelicalSequence analysisAdd
BLAST
Topological domaini69 – 283215PeriplasmicSequence analysisAdd
BLAST
Transmembranei284 – 30421HelicalSequence analysisAdd
BLAST
Topological domaini305 – 596292CytoplasmicSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 596596Sensor protein ChvGPRO_0000074720Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei367 – 3671PhosphohistidineBy similarity

Keywords - PTMi

Phosphoprotein

Interactioni

Protein-protein interaction databases

STRINGi176299.Atu0033.

Structurei

3D structure databases

ProteinModelPortaliQ07737.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini301 – 35656HAMPPROSITE-ProRule annotationAdd
BLAST
Domaini364 – 592229Histidine kinasePROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 1 HAMP domain.PROSITE-ProRule annotation
Contains 1 histidine kinase domain.PROSITE-ProRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105EB3. Bacteria.
COG0642. LUCA.
HOGENOMiHOG000226685.
KOiK14980.
OMAiPGIRSEN.

Family and domain databases

CDDicd06225. HAMP. 1 hit.
Gene3Di1.10.287.130. 1 hit.
3.30.565.10. 1 hit.
InterProiIPR003660. HAMP_dom.
IPR003594. HATPase_C.
IPR005467. His_kinase_dom.
IPR003661. HisK_dim/P.
IPR025908. Sensor_TM1.
IPR004358. Sig_transdc_His_kin-like_C.
IPR025919. Stimulus_sens_dom.
[Graphical view]
PfamiPF00672. HAMP. 1 hit.
PF02518. HATPase_c. 1 hit.
PF00512. HisKA. 1 hit.
PF13755. Sensor_TM1. 1 hit.
PF13756. Stimulus_sens_1. 1 hit.
[Graphical view]
PRINTSiPR00344. BCTRLSENSOR.
SMARTiSM00304. HAMP. 1 hit.
SM00387. HATPase_c. 1 hit.
SM00388. HisKA. 1 hit.
[Graphical view]
SUPFAMiSSF47384. SSF47384. 1 hit.
SSF55874. SSF55874. 1 hit.
PROSITEiPS50885. HAMP. 1 hit.
PS50109. HIS_KIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q07737-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLKKTPETVS DSDDAEERGS ERRHRIHPLT IIRRIFGNAV FSSLTRRILF
60 70 80 90 100
FNVAATVVLV GGILYLNQFR EGLIDARVES LLTQGEIIAG AVSASASVDT
110 120 130 140 150
NSITINPEKL LELQAGQSIT PAPNDEDLSF PINPERVAPV LRRLISPTRT
160 170 180 190 200
RARLFDADAN LLLDSRHLYS RGQVLRFDLP PVTPETQTWG DWFTSMFNRM
210 220 230 240 250
LQPSSLPQYK EAPGGDGSIY PEVMNALTGV RGAVVRVTEK GELIVSVAVP
260 270 280 290 300
VQRFRAVLGV LLLSTQAGDI DKIVHAERLA IMRVFGIATL VNIVLSLLLS
310 320 330 340 350
STIATPLRRL SAAAIRVRRG ARTREEIPDF SARQDEIGNL SIALREMTTA
360 370 380 390 400
LYDRIDAIES FAADVSHELK NPLTSLRSAV ETLPRAKTEE SKQRLTEIIF
410 420 430 440 450
HDVRRLDRLI SDISDASRLD AELARADASP LDLDVLMKGL VDISRQISTK
460 470 480 490 500
KKSVAIDYVA DRKAGAKTSF VVNGHDLRIG QIVTNLIENA RSFVSEESGR
510 520 530 540 550
ITVRLSRHKD RCIVQVEDNG PGIQAEDIDR IFERFYTDRP ASEGFGQNSG
560 570 580 590
LGLSISRQIA EAHGGSLRAE NVVDKYGVIS GARFTLSLPA AETHER
Length:596
Mass (Da):65,722
Last modified:March 27, 2002 - v2
Checksum:i8931990E49736C4B
GO

Sequence cautioni

The sequence AAA03552 differs from that shown. Reason: Frameshift at positions 18, 152, 183, 216, 234 and 567. Curated

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti94 – 941A → R in AAA03552 (PubMed:8407839).Curated
Sequence conflicti236 – 2361R → P (PubMed:8407839).Curated
Sequence conflicti314 – 3185AIRVR → RSGA in AAA03552 (PubMed:8407839).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L18860 Unassigned DNA. Translation: AAA03552.1. Frameshift.
AE007869 Genomic DNA. Translation: AAK85857.1.
PIRiA49902.
AB2581.
H97362.
RefSeqiNP_353072.1. NC_003062.2.
WP_006311105.1. NC_003062.2.

Genome annotation databases

EnsemblBacteriaiAAK85857; AAK85857; Atu0033.
GeneIDi1132071.
KEGGiatu:Atu0033.
PATRICi20809754. VBIAgrTum91616_0033.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L18860 Unassigned DNA. Translation: AAA03552.1. Frameshift.
AE007869 Genomic DNA. Translation: AAK85857.1.
PIRiA49902.
AB2581.
H97362.
RefSeqiNP_353072.1. NC_003062.2.
WP_006311105.1. NC_003062.2.

3D structure databases

ProteinModelPortaliQ07737.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi176299.Atu0033.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAK85857; AAK85857; Atu0033.
GeneIDi1132071.
KEGGiatu:Atu0033.
PATRICi20809754. VBIAgrTum91616_0033.

Phylogenomic databases

eggNOGiENOG4105EB3. Bacteria.
COG0642. LUCA.
HOGENOMiHOG000226685.
KOiK14980.
OMAiPGIRSEN.

Enzyme and pathway databases

BioCyciAGRO:ATU0033-MONOMER.
BRENDAi2.7.13.3. 200.

Family and domain databases

CDDicd06225. HAMP. 1 hit.
Gene3Di1.10.287.130. 1 hit.
3.30.565.10. 1 hit.
InterProiIPR003660. HAMP_dom.
IPR003594. HATPase_C.
IPR005467. His_kinase_dom.
IPR003661. HisK_dim/P.
IPR025908. Sensor_TM1.
IPR004358. Sig_transdc_His_kin-like_C.
IPR025919. Stimulus_sens_dom.
[Graphical view]
PfamiPF00672. HAMP. 1 hit.
PF02518. HATPase_c. 1 hit.
PF00512. HisKA. 1 hit.
PF13755. Sensor_TM1. 1 hit.
PF13756. Stimulus_sens_1. 1 hit.
[Graphical view]
PRINTSiPR00344. BCTRLSENSOR.
SMARTiSM00304. HAMP. 1 hit.
SM00387. HATPase_c. 1 hit.
SM00388. HisKA. 1 hit.
[Graphical view]
SUPFAMiSSF47384. SSF47384. 1 hit.
SSF55874. SSF55874. 1 hit.
PROSITEiPS50885. HAMP. 1 hit.
PS50109. HIS_KIN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiCHVG_AGRFC
AccessioniPrimary (citable) accession number: Q07737
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: March 27, 2002
Last modified: September 7, 2016
This is version 121 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.