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Protein

Putative carboxymethylenebutenolidase

Gene

YDL086W

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Catalytic activityi

4-carboxymethylenebut-2-en-4-olide + H2O = 4-oxohex-2-enedioate.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei130By similarity1
Active sitei191By similarity1
Active sitei223By similarity1

GO - Molecular functioni

  • carboxymethylenebutenolidase activity Source: SGD

Keywordsi

Molecular functionHydrolase

Enzyme and pathway databases

BioCyciYEAST:YDL086W-MONOMER

Protein family/group databases

ESTHERiyeast-dlhh Dienelactone_hydrolase

Names & Taxonomyi

Protein namesi
Recommended name:
Putative carboxymethylenebutenolidase (EC:3.1.1.45)
Alternative name(s):
Dienelactone hydrolase
Short name:
DLH
Gene namesi
Ordered Locus Names:YDL086W
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome IV

Organism-specific databases

EuPathDBiFungiDB:YDL086W
SGDiS000002244 YDL086W

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001615851 – 273Putative carboxymethylenebutenolidaseAdd BLAST273

Proteomic databases

MaxQBiQ07505
PaxDbiQ07505
PRIDEiQ07505

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
PRP40P332032EBI-5951,EBI-701

Protein-protein interaction databases

BioGridi31974, 45 interactors
DIPiDIP-3879N
IntActiQ07505, 8 interactors
MINTiQ07505
STRINGi4932.YDL086W

Structurei

3D structure databases

ProteinModelPortaliQ07505
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the dienelactone hydrolase family.Curated

Phylogenomic databases

HOGENOMiHOG000157122
InParanoidiQ07505
KOiK01061
OMAiHTFMRDD
OrthoDBiEOG092C44SV

Family and domain databases

Gene3Di3.40.50.1820, 1 hit
InterProiView protein in InterPro
IPR029058 AB_hydrolase
IPR002925 Dienelactn_hydro
PfamiView protein in Pfam
PF01738 DLH, 1 hit
SUPFAMiSSF53474 SSF53474, 1 hit

Sequencei

Sequence statusi: Complete.

Q07505-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLITETFHDV QTSYGTTLRI YVYSPKIAGY PQAKFPGVIL YSEIYQVTGP
60 70 80 90 100
VRRFGQRIAS EGYVVVAPAI YHNFMGPEAL PYDVQGTDIG NEYKIKKPLE
110 120 130 140 150
SYDEDNKLCC DLLFQLPQFD GKRIGSTGMC LGGHLAFRAL LDKRVTCATC
160 170 180 190 200
FFPTDIHSRT LGLGQNDNSL ERVSKELGNN QEMVLIFGTA DTHVDPQGRD
210 220 230 240 250
LIRKTLRDHG VKFTFLEILA AQHAFIRDEF SKGRFDSAIT QSCLGFLFEQ
260 270
FNRKLRIDLG EFVDDNTPLE HVC
Length:273
Mass (Da):30,837
Last modified:November 1, 1996 - v1
Checksum:i9A4A9B7577243D46
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z74134 Genomic DNA Translation: CAA98652.1
BK006938 Genomic DNA Translation: DAA11772.1
PIRiS67622
RefSeqiNP_010197.1, NM_001180145.1

Genome annotation databases

EnsemblFungiiYDL086W; YDL086W; YDL086W
GeneIDi851472
KEGGisce:YDL086W

Similar proteinsi

Entry informationi

Entry nameiDLHH_YEAST
AccessioniPrimary (citable) accession number: Q07505
Secondary accession number(s): D6VRR2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 15, 1998
Last sequence update: November 1, 1996
Last modified: May 23, 2018
This is version 132 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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