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Q07505 (DLHH_YEAST) Reviewed, UniProtKB/Swiss-Prot

Last modified April 3, 2013. Version 98. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Interactions·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Putative carboxymethylenebutenolidase

EC=3.1.1.45
Alternative name(s):
Dienelactone hydrolase
Short name=DLH
Gene names
Ordered Locus Names:YDL086W
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]
Taxonomic identifier559292 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces

Protein attributes

Sequence length273 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Catalytic activity

4-carboxymethylenebut-2-en-4-olide + H2O = 4-oxohex-2-enedioate.

Sequence similarities

Belongs to the dienelactone hydrolase family.

Binary interactions

With

Entry

#Exp.

IntAct

Notes

PRP40P332032EBI-5951,EBI-701

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 273273Putative carboxymethylenebutenolidase
PRO_0000161585

Sites

Active site1301 By similarity
Active site1911 By similarity
Active site2231 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q07505 [UniParc].

Last modified November 1, 1996. Version 1.
Checksum: 9A4A9B7577243D46

FASTA27330,837
        10         20         30         40         50         60 
MLITETFHDV QTSYGTTLRI YVYSPKIAGY PQAKFPGVIL YSEIYQVTGP VRRFGQRIAS 

        70         80         90        100        110        120 
EGYVVVAPAI YHNFMGPEAL PYDVQGTDIG NEYKIKKPLE SYDEDNKLCC DLLFQLPQFD 

       130        140        150        160        170        180 
GKRIGSTGMC LGGHLAFRAL LDKRVTCATC FFPTDIHSRT LGLGQNDNSL ERVSKELGNN 

       190        200        210        220        230        240 
QEMVLIFGTA DTHVDPQGRD LIRKTLRDHG VKFTFLEILA AQHAFIRDEF SKGRFDSAIT 

       250        260        270 
QSCLGFLFEQ FNRKLRIDLG EFVDDNTPLE HVC 

« Hide

References

« Hide 'large scale' references
[1]"The nucleotide sequence of Saccharomyces cerevisiae chromosome IV."
Jacq C., Alt-Moerbe J., Andre B., Arnold W., Bahr A., Ballesta J.P.G., Bargues M., Baron L., Becker A., Biteau N., Bloecker H., Blugeon C., Boskovic J., Brandt P., Brueckner M., Buitrago M.J., Coster F., Delaveau T. expand/collapse author list , del Rey F., Dujon B., Eide L.G., Garcia-Cantalejo J.M., Goffeau A., Gomez-Peris A., Granotier C., Hanemann V., Hankeln T., Hoheisel J.D., Jaeger W., Jimenez A., Jonniaux J.-L., Kraemer C., Kuester H., Laamanen P., Legros Y., Louis E.J., Moeller-Rieker S., Monnet A., Moro M., Mueller-Auer S., Nussbaumer B., Paricio N., Paulin L., Perea J., Perez-Alonso M., Perez-Ortin J.E., Pohl T.M., Prydz H., Purnelle B., Rasmussen S.W., Remacha M.A., Revuelta J.L., Rieger M., Salom D., Saluz H.P., Saiz J.E., Saren A.-M., Schaefer M., Scharfe M., Schmidt E.R., Schneider C., Scholler P., Schwarz S., Soler-Mira A., Urrestarazu L.A., Verhasselt P., Vissers S., Voet M., Volckaert G., Wagner G., Wambutt R., Wedler E., Wedler H., Woelfl S., Harris D.E., Bowman S., Brown D., Churcher C.M., Connor R., Dedman K., Gentles S., Hamlin N., Hunt S., Jones L., McDonald S., Murphy L.D., Niblett D., Odell C., Oliver K., Rajandream M.A., Richards C., Shore L., Walsh S.V., Barrell B.G., Dietrich F.S., Mulligan J.T., Allen E., Araujo R., Aviles E., Berno A., Carpenter J., Chen E., Cherry J.M., Chung E., Duncan M., Hunicke-Smith S., Hyman R.W., Komp C., Lashkari D., Lew H., Lin D., Mosedale D., Nakahara K., Namath A., Oefner P., Oh C., Petel F.X., Roberts D., Schramm S., Schroeder M., Shogren T., Shroff N., Winant A., Yelton M.A., Botstein D., Davis R.W., Johnston M., Andrews S., Brinkman R., Cooper J., Ding H., Du Z., Favello A., Fulton L., Gattung S., Greco T., Hallsworth K., Hawkins J., Hillier L.W., Jier M., Johnson D., Johnston L., Kirsten J., Kucaba T., Langston Y., Latreille P., Le T., Mardis E., Menezes S., Miller N., Nhan M., Pauley A., Peluso D., Rifkin L., Riles L., Taich A., Trevaskis E., Vignati D., Wilcox L., Wohldman P., Vaudin M., Wilson R., Waterston R., Albermann K., Hani J., Heumann K., Kleine K., Mewes H.-W., Zollner A., Zaccaria P.
Nature 387:75-78(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[2]Saccharomyces Genome Database
Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: ATCC 204508 / S288c.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
Z74134 Genomic DNA. Translation: CAA98652.1.
BK006938 Genomic DNA. Translation: DAA11772.1.
PIRS67622.
RefSeqNP_010197.1. NM_001180145.1.

3D structure databases

ProteinModelPortalQ07505.
ModBaseSearch...

Protein-protein interaction databases

DIPDIP-3879N.
IntActQ07505. 8 interactions.
MINTMINT-483224.
STRING4932.YDL086W.

Proteomic databases

PaxDbQ07505.
PeptideAtlasQ07505.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiYDL086W; YDL086W; YDL086W.
GeneID851472.
KEGGsce:YDL086W.

Organism-specific databases

CYGDYDL086w.
SGDS000002244. YDL086W.

Phylogenomic databases

eggNOGCOG0412.
HOGENOMHOG000157122.
KOK01061.
OMAWGKQDPH.
OrthoDBEOG4XSPZS.

Gene expression databases

GenevestigatorQ07505.
GermOnlineYDL086W. Saccharomyces cerevisiae.

Family and domain databases

InterProIPR002925. Dienelactn_hydro.
[Graphical view]
PfamPF01738. DLH. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio968768.

Entry information

Entry nameDLHH_YEAST
AccessionPrimary (citable) accession number: Q07505
Secondary accession number(s): D6VRR2
Entry history
Integrated into UniProtKB/Swiss-Prot: December 15, 1998
Last sequence update: November 1, 1996
Last modified: April 3, 2013
This is version 98 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD

Yeast chromosome IV

Yeast (Saccharomyces cerevisiae) chromosome IV: entries and gene names

SIMILARITY comments

Index of protein domains and families