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Protein
Submitted name:

Chorionic somatomammotropin-3

Gene

GHB2

Organism
Macaca mulatta (Rhesus macaque)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

Keywords - Molecular functioni

HormoneUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Chorionic somatomammotropin-3Imported
Submitted name:
Growth hormone B2Imported
Gene namesi
Name:GHB2Imported
OrganismiMacaca mulatta (Rhesus macaque)Imported
Taxonomic identifieri9544 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniCercopithecidaeCercopithecinaeMacaca

Subcellular locationi

  • Secreted UniRule annotationSAAS annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

SecretedSAAS annotation

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2424Sequence analysisAdd
BLAST
Chaini25 – 217193Sequence analysisPRO_5006963746Add
BLAST

Keywords - PTMi

Disulfide bondSAAS annotation

Structurei

3D structure databases

ProteinModelPortaliQ07369.
SMRiQ07369. Positions 28-216.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the somatotropin/prolactin family.UniRule annotationSAAS annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

HOGENOMiHOG000068443.
HOVERGENiHBG011318.

Family and domain databases

Gene3Di1.20.1250.10. 1 hit.
InterProiIPR009079. 4_helix_cytokine-like_core.
IPR012351. 4_helix_cytokine_core.
IPR001400. Somatotropin.
IPR018116. Somatotropin_CS.
[Graphical view]
PANTHERiPTHR11417. PTHR11417. 1 hit.
PfamiPF00103. Hormone_1. 1 hit.
[Graphical view]
PRINTSiPR00836. SOMATOTROPIN.
SUPFAMiSSF47266. SSF47266. 1 hit.
PROSITEiPS00266. SOMATOTROPIN_1. 1 hit.
PS00338. SOMATOTROPIN_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q07369-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAAGSRTSLL LVFALLCLPW LQEAGRVPSV PLSRLFDNIM MQAHRLHQLA
60 70 80 90 100
FDTYQEFEKT YIPKEKKHSL MGNPQASFCF SESIPTPSNR EETQQKSNLE
110 120 130 140 150
LLRISLLLIQ SWLEPVQLLG SVFANNLVYG TSESDAYDLL KNLEEGIQTL
160 170 180 190 200
MRRLQDGSPR TGQIFKQTYS TFDTDSQNDD SLLKNYELLH CFRKDMDMVE
210
TFLRMVQCRT VEGSCGF
Length:217
Mass (Da):24,874
Last modified:November 1, 1996 - v1
Checksum:iF1EB6AFDBBA1B185
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L16554 mRNA. Translation: AAA18841.1.
LM644155 mRNA. Translation: CDW51402.1.
PIRiI67409.
RefSeqiNP_001036205.1. NM_001042740.1.
UniGeneiMmu.12494.

Genome annotation databases

GeneIDi717562.
KEGGimcc:717562.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L16554 mRNA. Translation: AAA18841.1.
LM644155 mRNA. Translation: CDW51402.1.
PIRiI67409.
RefSeqiNP_001036205.1. NM_001042740.1.
UniGeneiMmu.12494.

3D structure databases

ProteinModelPortaliQ07369.
SMRiQ07369. Positions 28-216.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi717562.
KEGGimcc:717562.

Organism-specific databases

CTDi1443.

Phylogenomic databases

HOGENOMiHOG000068443.
HOVERGENiHBG011318.

Family and domain databases

Gene3Di1.20.1250.10. 1 hit.
InterProiIPR009079. 4_helix_cytokine-like_core.
IPR012351. 4_helix_cytokine_core.
IPR001400. Somatotropin.
IPR018116. Somatotropin_CS.
[Graphical view]
PANTHERiPTHR11417. PTHR11417. 1 hit.
PfamiPF00103. Hormone_1. 1 hit.
[Graphical view]
PRINTSiPR00836. SOMATOTROPIN.
SUPFAMiSSF47266. SSF47266. 1 hit.
PROSITEiPS00266. SOMATOTROPIN_1. 1 hit.
PS00338. SOMATOTROPIN_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Cloning of four growth hormone/chorionic somatomammotropin-related complementary deoxyribonucleic acids differentially expressed during pregnancy in the rhesus monkey placenta."
    Golos T.G., Durning M., Fisher J.M., Fowler P.D.
    Endocrinology 133:1744-1752(1993) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: Midpregnancy placentaImported.
  2. "Third party data gene data set of eutherian growth hormone genes."
    Premzl M.
    Genomics Data 6:166-169(2015) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
  3. "Curated eutherian third party data gene data sets."
    Premzl M.
    Data Brief 6:208-213(2016) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiQ07369_MACMU
AccessioniPrimary (citable) accession number: Q07369
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: June 8, 2016
This is version 90 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.