##gff-version 3
Q07352	UniProtKB	Chain	1	338	.	.	.	ID=PRO_0000089167;Note=MRNA decay activator protein ZFP36L1	
Q07352	UniProtKB	Zinc finger	114	142	.	.	.	Note=C3H1-type 1;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00723	
Q07352	UniProtKB	Zinc finger	152	180	.	.	.	Note=C3H1-type 2;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00723	
Q07352	UniProtKB	Region	1	111	.	.	.	Note=Necessary and sufficient for the association with mRNA decay enzymes and mRNA decay activation;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:15687258;Dbxref=PMID:15687258	
Q07352	UniProtKB	Region	93	113	.	.	.	Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q07352	UniProtKB	Region	185	338	.	.	.	Note=Necessary for mRNA decay activation;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:15687258;Dbxref=PMID:15687258	
Q07352	UniProtKB	Region	273	338	.	.	.	Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q07352	UniProtKB	Compositional bias	289	338	.	.	.	Note=Polar residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q07352	UniProtKB	Modified residue	54	54	.	.	.	Note=Phosphoserine%3B by MAPKAPK2;Ontology_term=ECO:0000269,ECO:0007744,ECO:0007744,ECO:0007744;evidence=ECO:0000269|PubMed:18326031,ECO:0007744|PubMed:21406692,ECO:0007744|PubMed:23186163,ECO:0007744|PubMed:24275569;Dbxref=PMID:18326031,PMID:21406692,PMID:23186163,PMID:24275569	
Q07352	UniProtKB	Modified residue	90	90	.	.	.	Note=Phosphoserine%3B by PKB/AKT1;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:15538381;Dbxref=PMID:15538381	
Q07352	UniProtKB	Modified residue	92	92	.	.	.	Note=Phosphoserine%3B by PKB/AKT1 and MAPKAPK2;Ontology_term=ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:15538381,ECO:0000269|PubMed:18326031;Dbxref=PMID:15538381,PMID:18326031	
Q07352	UniProtKB	Modified residue	203	203	.	.	.	Note=Phosphoserine%3B by PKB/AKT1 and MAPKAPK2;Ontology_term=ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:17030608,ECO:0000269|PubMed:18326031;Dbxref=PMID:17030608,PMID:18326031	
Q07352	UniProtKB	Modified residue	318	318	.	.	.	Note=Phosphoserine;Ontology_term=ECO:0007744;evidence=ECO:0007744|PubMed:24275569;Dbxref=PMID:24275569	
Q07352	UniProtKB	Modified residue	334	334	.	.	.	Note=Phosphoserine%3B by RPS6KA1;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:25106868;Dbxref=PMID:25106868	
Q07352	UniProtKB	Mutagenesis	54	54	.	.	.	Note=Inhibits MAPKAPK2-mediated ARE-containing mRNA stabilization%3B when associated with A-92 and A-203. S->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:18326031;Dbxref=PMID:18326031	
Q07352	UniProtKB	Mutagenesis	90	90	.	.	.	Note=Inhibits interaction with 14-3-3 proteins and AKT1-mediated ARE-containing mRNA stabilization%2C but does not affect ARE binding%3B when associated with A-92. S->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:15538381;Dbxref=PMID:15538381	
Q07352	UniProtKB	Mutagenesis	92	92	.	.	.	Note=Inhibits MAPKAPK2-mediated ARE-containing mRNA stabilization%3B when associated with A-54 and A-203. Inhibits interaction with 14-3-3 proteins and AKT1-mediated ARE-containing mRNA stabilization%3B when associated with A-203. Inhibits interaction with 14-3-3 proteins and AKT1-mediated ARE-containing mRNA stabilization%2C but does not affect ARE binding%3B when associated with A-90. S->A;Ontology_term=ECO:0000269,ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:15538381,ECO:0000269|PubMed:17030608,ECO:0000269|PubMed:18326031;Dbxref=PMID:15538381,PMID:17030608,PMID:18326031	
Q07352	UniProtKB	Mutagenesis	120	120	.	.	.	Note=Reduces binding to ARE-containing mRNAs and ARE-mediated mRNA decay. Inhibits binding to ARE-containing mRNAs and ARE-mediated mRNA decay%3B when associated with R-158. C->R;Ontology_term=ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:12198173,ECO:0000269|PubMed:24700863;Dbxref=PMID:12198173,PMID:24700863	
Q07352	UniProtKB	Mutagenesis	158	158	.	.	.	Note=Reduces binding to ARE-containing mRNAs and ARE-mediated mRNA decay. Inhibits binding to ARE-containing mRNAs and ARE-mediated mRNA decay%3B when associated with R-120. C->R;Ontology_term=ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:12198173,ECO:0000269|PubMed:24700863;Dbxref=PMID:12198173,PMID:24700863	
Q07352	UniProtKB	Mutagenesis	203	203	.	.	.	Note=Inhibits interaction with 14-3-3 proteins and AKT1-mediated ARE-containing mRNA stabilization%3B when associated with A-92. Inhibits MAPKAPK2-mediated ARE-containing mRNA stabilization%3B when associated with A-54 and A-92. S->A;Ontology_term=ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:17030608,ECO:0000269|PubMed:18326031;Dbxref=PMID:17030608,PMID:18326031	
Q07352	UniProtKB	Mutagenesis	334	334	.	.	.	Note=Inhibits p38 MAPK-mediated LDLR mRNA stabilization%2C but does not inhibit interaction with CNOT1 and CNOT7%3B when associated with A-336. S->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:25106868;Dbxref=PMID:25106868	
Q07352	UniProtKB	Mutagenesis	336	336	.	.	.	Note=Inhibits p38 MAPK-mediated LDLR mRNA stabilization%2C but does not inhibit interaction with CNOT1 and CNOT7%3B when associated with A-334. S->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:25106868;Dbxref=PMID:25106868	
Q07352	UniProtKB	Sequence conflict	63	63	.	.	.	Note=H->R;Ontology_term=ECO:0000305;evidence=ECO:0000305