Reviewed, UniProtKB/Swiss-Prot Q07310 (NRX3A_RAT)

Names and origin

Protein names

Recommended name:
    Neurexin-3-alpha
Alternative name(s):
    Neurexin III-alpha

Gene names

Name:

Nrxn3

Organism

Rattus norvegicus (Rat)

Taxonomic identifier

10116 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Rattus

Protein attributes

Sequence length	1578 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at protein level.

General annotation (Comments)

Function	Neuronal cell surface protein that may be involved in cell recognition and cell adhesion. May mediate intracellular signaling.
Subunit structure	The laminin G-like domain 2 binds to NXPH1. Isoforms alpha 4B bind to alpha-dystroglycan. The cytoplasmic C-terminal region binds to CASK.
Subcellular location	Cell membrane; Single-pass type I membrane proteinPotential. Secreted. Note= Some isoforms seems to be secreted.
Tissue specificity	Brain.
Sequence similarities	Belongs to the neurexin family. Contains 3 EGF-like domains. Contains 6 laminin G-like domains.

Ontologies

Keywords
Biological process	Cell adhesion
Cellular component	Cell membrane Membrane Secreted
Coding sequence diversity	Alternative splicing
Domain	EGF-like domain Repeat Signal Transmembrane
Ligand	Calcium Metal-binding
PTM	Glycoprotein
Technical term	Direct protein sequencing
Gene Ontology (GO)
Biological process	cell adhesion Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	extracellular region Inferred from electronic annotation. Source: UniProtKB-KW integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membrane Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	calcium ion binding Inferred from electronic annotation. Source: UniProtKB-KW protein binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Alternative products

This entry describes 19 isoforms produced by alternative splicing. [Align] [Select]

Notes: There are five major alternatively spliced sites, each of which may be spliced in up to twelve different ways. Combinatorial splicing at each of these five sites may lead to the generation of at least 288 isoforms but for simplicity only individual splice events are explicitly described below. Isoforms Alpha 5A to isoform Alpha 5H lack the transmembrane domain. Experimental confirmation may be lacking for some isoforms.

Isoform 1 (identifier: Q07310-1)

Also known as: Alpha-5I;

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Isoform 2 (identifier: Q07310-2)

Also known as: Alpha-1B;

The sequence of this isoform differs from the canonical sequence as follows:
     253-256: Missing.

Isoform 3 (identifier: Q07310-3)

Also known as: Alpha-1C;

The sequence of this isoform differs from the canonical sequence as follows:
     237-242: Missing.

Isoform 4 (identifier: Q07310-4)

Also known as: Alpha-1D;

The sequence of this isoform differs from the canonical sequence as follows:
     237-242: Missing.
     253-256: Missing.

Isoform 5 (identifier: Q07310-5)

Also known as: Alpha-1E;

The sequence of this isoform differs from the canonical sequence as follows:
     243-256: Missing.

Isoform 6 (identifier: Q07310-6)

Also known as: Alpha-1F;

The sequence of this isoform differs from the canonical sequence as follows:
     237-256: Missing.

Isoform 7 (identifier: Q07310-7)

Also known as: Alpha-3B;

The sequence of this isoform differs from the canonical sequence as follows:
     754-763: DCIRINCNSS → G

Isoform 8 (identifier: Q07310-8)

Also known as: Alpha-4B;

The sequence of this isoform differs from the canonical sequence as follows:
     1210-1239: Missing.

Isoform 9 (identifier: Q07310-9)

Also known as: Alpha-5A;

The sequence of this isoform differs from the canonical sequence as follows:
     1372-1478: Missing.
     1479-1578: ANPTEPGIRR...QKNKDKEYYV → ARSSNAARIT...LKFMCCHPPP

Isoform 10 (identifier: Q07310-10)

Also known as: Alpha-5B;

The sequence of this isoform differs from the canonical sequence as follows:
     1369-1371: Missing.
     1372-1478: Missing.
     1479-1578: ANPTEPGIRR...QKNKDKEYYV → ARSSNAARIT...LKFMCCHPPP

Isoform 11 (identifier: Q07310-11)

Also known as: Alpha-5C;

The sequence of this isoform differs from the canonical sequence as follows:
     1372-1478: Missing.
     1479-1578: ANPTEPGIRR...QKNKDKEYYV → VLERRIILNLKTNAHPKSLQSKTC

Isoform 12 (identifier: Q07310-12)

Also known as: Alpha-5D;

The sequence of this isoform differs from the canonical sequence as follows:
     1369-1371: Missing.
     1372-1478: Missing.
     1479-1578: ANPTEPGIRR...QKNKDKEYYV → VLERRIILNLKTNAHPKSLQSKTC

Isoform 13 (identifier: Q07310-13)

Also known as: Alpha-5E;

The sequence of this isoform differs from the canonical sequence as follows:
     1372-1478: Missing.
     1479-1578: ANPTEPGIRR...QKNKDKEYYV → DILLKSF

Isoform 14 (identifier: Q07310-14)

Also known as: Alpha-5F;

The sequence of this isoform differs from the canonical sequence as follows:
     1369-1371: Missing.
     1372-1478: Missing.
     1479-1578: ANPTEPGIRR...QKNKDKEYYV → DILLKSF

Isoform 15 (identifier: Q07310-15)

Also known as: Alpha-5G;

The sequence of this isoform differs from the canonical sequence as follows:
     1372-1478: Missing.
     1479-1578: ANPTEPGIRR...QKNKDKEYYV → ATTTTKKSNFQECGNSICPRAFLHNFLL

Isoform 16 (identifier: Q07310-16)

Also known as: Alpha-5H;

The sequence of this isoform differs from the canonical sequence as follows:
     1369-1371: Missing.
     1372-1478: Missing.
     1479-1578: ANPTEPGIRR...QKNKDKEYYV → ATTTTKKSNFQECGNSICPRAFLHNFLL

Isoform 17 (identifier: Q07310-17)

Also known as: Alpha-5J;

The sequence of this isoform differs from the canonical sequence as follows:
     1369-1371: Missing.

Isoform 18 (identifier: Q07310-18)

Also known as: Alpha-5K;

The sequence of this isoform differs from the canonical sequence as follows:
     1372-1478: Missing.

Isoform 19 (identifier: Q07310-19)

Also known as: Alpha-5L;

The sequence of this isoform differs from the canonical sequence as follows:
     1369-1371: Missing.
     1372-1478: Missing.

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 27	27
	Chain	28 – 1578	1551	Neurexin-3-alpha		PRO_0000019500
Regions
	Topological domain	28 – 1503	1476	Extracellular Potential
	Transmembrane	1504 – 1524	21	Potential
	Topological domain	1525 – 1578	54	Cytoplasmic Potential
	Domain	28 – 202	175	Laminin G-like 1
	Domain	198 – 235	38	EGF-like 1
	Domain	260 – 444	185	Laminin G-like 2
	Domain	451 – 643	193	Laminin G-like 3
	Domain	647 – 684	38	EGF-like 2
	Domain	689 – 861	173	Laminin G-like 4
	Domain	875 – 1050	176	Laminin G-like 5
	Domain	1053 – 1090	38	EGF-like 3
	Domain	1094 – 1294	201	Laminin G-like 6
	Compositional bias	282 – 285	4	Poly-Ser
	Compositional bias	1323 – 1326	4	Poly-Thr
	Compositional bias	1329 – 1332	4	Poly-Thr
	Compositional bias	1407 – 1410	4	Poly-Thr
	Compositional bias	1422 – 1425	4	Poly-Ser
	Compositional bias	1511 – 1514	4	Poly-Ala
Sites
	Metal binding	308	1	Calcium By similarity
	Metal binding	325	1	Calcium; via carbonyl oxygen By similarity
	Metal binding	378	1	Calcium; via carbonyl oxygen By similarity
Amino acid modifications
	Glycosylation	58	1	N-linked (GlcNAc...) Potential
	Glycosylation	105	1	N-linked (GlcNAc...) Potential
	Glycosylation	761	1	N-linked (GlcNAc...) Potential
	Glycosylation	1193	1	N-linked (GlcNAc...) Potential
	Glycosylation	1291	1	N-linked (GlcNAc...) Potential
	Glycosylation	1335	1	N-linked (GlcNAc...) Potential
	Glycosylation	1500	1	N-linked (GlcNAc...) Potential
	Disulfide bond	202 ↔ 213		By similarity
	Disulfide bond	207 ↔ 222		By similarity
	Disulfide bond	224 ↔ 234		By similarity
	Disulfide bond	408 ↔ 444		By similarity
	Disulfide bond	614 ↔ 643		By similarity
	Disulfide bond	651 ↔ 662		By similarity
	Disulfide bond	656 ↔ 671		By similarity
	Disulfide bond	673 ↔ 683		By similarity
	Disulfide bond	1022 ↔ 1050		By similarity
	Disulfide bond	1057 ↔ 1068		By similarity
	Disulfide bond	1062 ↔ 1077		By similarity
	Disulfide bond	1079 ↔ 1089		By similarity
Natural variations
	Alternative sequence	237 – 256	20	Missing in isoform 6.		VSP_003522
	Alternative sequence	237 – 242	6	Missing in isoform 3 and isoform 4.		VSP_003521
	Alternative sequence	243 – 256	14	Missing in isoform 5.		VSP_003523
	Alternative sequence	253 – 256	4	Missing in isoform 2 and isoform 4.		VSP_003524
	Alternative sequence	754 – 763	10	DCIRINCNSS → G in isoform 7.		VSP_003525
	Alternative sequence	1210 – 1239	30	Missing in isoform 8.		VSP_003526
	Alternative sequence	1369 – 1371	3	Missing in isoform 10, isoform 12, isoform 14, isoform 16, isoform 17 and isoform 19.		VSP_003527
	Alternative sequence	1372 – 1478	107	Missing in isoform 9, isoform 10, isoform 11, isoform 12, isoform 13, isoform 14, isoform 15, isoform 16, isoform 18 and isoform 19.		VSP_003528
	Alternative sequence	1479 – 1578	100	ANPTE…KEYYV → VLERRIILNLKTNAHPKSLQ SKTC in isoform 11 and isoform 12.		VSP_003530
	Alternative sequence	1479 – 1578	100	ANPTE…KEYYV → DILLKSF in isoform 13 and isoform 14.		VSP_003531
	Alternative sequence	1479 – 1578	100	ANPTE…KEYYV → ATTTTKKSNFQECGNSICPR AFLHNFLL in isoform 15 and isoform 16.		VSP_003532
	Alternative sequence	1479 – 1578	100	ANPTE…KEYYV → ARSSNAARITPCRPYMDMAT HLHIYPSHLHLLCSTLIDTP LPFPHPFFPMLPPSLALLKF MCCHPPP in isoform 9 and isoform 10.		VSP_003529

Sequences

	Sequence		Length	Mass (Da)
	Isoform 1 (Alpha-5I) [UniParc]. Last modified November 1, 1996. Version 1. Checksum: 936CF8529143D0C7	FASTA	1,578	173,994
	10 20 30 40 50 60 MSFTLHSVFF TLKVSSFLGS LVGLCLGLEF MGLPNQWARY LRWDASTRSD LSFQFKTNVS 70 80 90 100 110 120 TGLLLYLDDG GVCDFLCLSL VDGRVQLRFS MDCAETTVLS NKQVNDSSWH FLMVSRDRVR 130 140 150 160 170 180 TGLVIDGEGQ SGELRAQRPY MDVVSDLFLG GGPADIRPSA LTLDGVQNMP GFKGLMLDLK 190 200 210 220 230 240 YGNSEPRLLG SQSVQLEAEG PCGERPCENG GICFLLDGHP TCDCSTTGYG GTLCSEDVSQ 250 260 270 280 290 300 GPGLSHLMMS EQGRSKAREE NVATFRGSEY LSYDLSQNPI QSSSSEITLS FKTWQRNGLI 310 320 330 340 350 360 LHTGKSADYV NLALKDGAVS LVINLGSGAF EAIVEPVNGK FNDNAWHDVK VTRNLRQVTI 370 380 390 400 410 420 SVDGILTTTG YTQEDYTMLG SDDSSYVGPS PSTADLPGSP VSNNFMGCLK EVVYKNNDIR 430 440 450 460 470 480 LELSRLARIG ATKMKIYGEV VFKCENVATL DPINFETPEA YISLPKWNTK RMGSISFDFR 490 500 510 520 530 540 TTEPNGLILL THGKPQERKD VRSQKNTKVD FFAVELLDGN LYLLLDMGSG TIKVKATQKK 550 560 570 580 590 600 ANDGEWYHVD IQRDGRSGTI SVNSRRTPFT ASGQSEILDL EGDMYLGGLP ENRAGLILPT 610 620 630 640 650 660 ELWTAMLNYG YVGCIRDLFI DGRSKNIRQL AEMQNAAGVK SSCSRMSAKQ CDSYPCKNNA 670 680 690 700 710 720 VCKDGWNRFI CDCTGTGYWG RTCEREASIL SYDGSMYMKV IMPMVMHTEA EDVSFRFMSQ 730 740 750 760 770 780 RAYGLLVATT SRDSADTLRL ELDGGRVKLM VNLDCIRINC NSSKGPETLY AGQKLNDNEW 790 800 810 820 830 840 HTVRVVRRGK SLKLTVDDDV AEGTMVGDHT RLEFHNIETG IMTEKRYISV VPSSFIGHLQ 850 860 870 880 890 900 SLMFNGLLYI DLCKNGDIDY CELKARFGLR NIIADPVTFK TKSSYLTLAT LQAYTSMHLF 910 920 930 940 950 960 FQFKTTSADG FILFNSGDGN NFIAVELVKG YIHYVFDLGN GPNVIKGNSD RPLNDNQWHN 970 980 990 1000 1010 1020 VVITRDNSNT HSLKVDTKVV TQVINGAKNL DLKGDLYMAG LAQGMYSNLP KLVASRDGFQ 1030 1040 1050 1060 1070 1080 GCLASVDLNG RLPDLINDAL HRSGQIDRGC EGPSTTCQED SCANQGVCMQ QWEGFTCDCS 1090 1100 1110 1120 1130 1140 MTSYSGNQCN DPGATYIFGK SGGLILYTWP ANDRPSTRSD RLAVGFSTTV KDGVLVRIDS 1150 1160 1170 1180 1190 1200 APGLGDFLQL HIEQGKIGVV FNIGTVDISI KEERTPVNDG KYHVVRFTRN GANATLQVDN 1210 1220 1230 1240 1250 1260 WPVNEHYPTG NTDNERRQMV KQKIPFKYNR PVEEWLQEKG RQLTIFNTQA QIAIGGKDKG 1270 1280 1290 1300 1310 1320 RLFQGQLSGL YYDGLKVLNM AAENNPNIKI NGSVRLVGEV PSVSGTTHTT SMPPEMSTTV 1330 1340 1350 1360 1370 1380 METTTTMATT TTRKNRSTAS IQPTSDDLVS SAECSSDDED FVECEPSTGR SDKSLSTSIF 1390 1400 1410 1420 1430 1440 EGGYKAHAPK WESKDFRPNK VSETSRTTTT SLSPELIRFT ASSSSGMVPK LPAGKMNNRD 1450 1460 1470 1480 1490 1500 LKPQPDIVLL PLPTAYELDS TKLKSPLITC PMFRNVPTAN PTEPGIRRVP GASEVIRESN 1510 1520 1530 1540 1550 1560 STTGMVVGIV AAAALCILIL LYAMYKYRNR DEGSYQVDET RNYISNSAQS NGTLMKEKQA 1570 SSKSGHKKQK NKDKEYYV
	Isoform 2 (Alpha-1B) [UniParc]. Checksum: A565F06AC79EBC8C		1,574	173,565
	10 20 30 40 50 60 MSFTLHSVFF TLKVSSFLGS LVGLCLGLEF MGLPNQWARY LRWDASTRSD LSFQFKTNVS 70 80 90 100 110 120 TGLLLYLDDG GVCDFLCLSL VDGRVQLRFS MDCAETTVLS NKQVNDSSWH FLMVSRDRVR 130 140 150 160 170 180 TGLVIDGEGQ SGELRAQRPY MDVVSDLFLG GGPADIRPSA LTLDGVQNMP GFKGLMLDLK 190 200 210 220 230 240 YGNSEPRLLG SQSVQLEAEG PCGERPCENG GICFLLDGHP TCDCSTTGYG GTLCSEDVSQ 250 260 270 280 290 300 GPGLSHLMMS EQAREENVAT FRGSEYLSYD LSQNPIQSSS SEITLSFKTW QRNGLILHTG 310 320 330 340 350 360 KSADYVNLAL KDGAVSLVIN LGSGAFEAIV EPVNGKFNDN AWHDVKVTRN LRQVTISVDG 370 380 390 400 410 420 ILTTTGYTQE DYTMLGSDDS SYVGPSPSTA DLPGSPVSNN FMGCLKEVVY KNNDIRLELS 430 440 450 460 470 480 RLARIGATKM KIYGEVVFKC ENVATLDPIN FETPEAYISL PKWNTKRMGS ISFDFRTTEP 490 500 510 520 530 540 NGLILLTHGK PQERKDVRSQ KNTKVDFFAV ELLDGNLYLL LDMGSGTIKV KATQKKANDG 550 560 570 580 590 600 EWYHVDIQRD GRSGTISVNS RRTPFTASGQ SEILDLEGDM YLGGLPENRA GLILPTELWT 610 620 630 640 650 660 AMLNYGYVGC IRDLFIDGRS KNIRQLAEMQ NAAGVKSSCS RMSAKQCDSY PCKNNAVCKD 670 680 690 700 710 720 GWNRFICDCT GTGYWGRTCE REASILSYDG SMYMKVIMPM VMHTEAEDVS FRFMSQRAYG 730 740 750 760 770 780 LLVATTSRDS ADTLRLELDG GRVKLMVNLD CIRINCNSSK GPETLYAGQK LNDNEWHTVR 790 800 810 820 830 840 VVRRGKSLKL TVDDDVAEGT MVGDHTRLEF HNIETGIMTE KRYISVVPSS FIGHLQSLMF 850 860 870 880 890 900 NGLLYIDLCK NGDIDYCELK ARFGLRNIIA DPVTFKTKSS YLTLATLQAY TSMHLFFQFK 910 920 930 940 950 960 TTSADGFILF NSGDGNNFIA VELVKGYIHY VFDLGNGPNV IKGNSDRPLN DNQWHNVVIT 970 980 990 1000 1010 1020 RDNSNTHSLK VDTKVVTQVI NGAKNLDLKG DLYMAGLAQG MYSNLPKLVA SRDGFQGCLA 1030 1040 1050 1060 1070 1080 SVDLNGRLPD LINDALHRSG QIDRGCEGPS TTCQEDSCAN QGVCMQQWEG FTCDCSMTSY 1090 1100 1110 1120 1130 1140 SGNQCNDPGA TYIFGKSGGL ILYTWPANDR PSTRSDRLAV GFSTTVKDGV LVRIDSAPGL 1150 1160 1170 1180 1190 1200 GDFLQLHIEQ GKIGVVFNIG TVDISIKEER TPVNDGKYHV VRFTRNGANA TLQVDNWPVN 1210 1220 1230 1240 1250 1260 EHYPTGNTDN ERRQMVKQKI PFKYNRPVEE WLQEKGRQLT IFNTQAQIAI GGKDKGRLFQ 1270 1280 1290 1300 1310 1320 GQLSGLYYDG LKVLNMAAEN NPNIKINGSV RLVGEVPSVS GTTHTTSMPP EMSTTVMETT 1330 1340 1350 1360 1370 1380 TTMATTTTRK NRSTASIQPT SDDLVSSAEC SSDDEDFVEC EPSTGRSDKS LSTSIFEGGY 1390 1400 1410 1420 1430 1440 KAHAPKWESK DFRPNKVSET SRTTTTSLSP ELIRFTASSS SGMVPKLPAG KMNNRDLKPQ 1450 1460 1470 1480 1490 1500 PDIVLLPLPT AYELDSTKLK SPLITCPMFR NVPTANPTEP GIRRVPGASE VIRESNSTTG 1510 1520 1530 1540 1550 1560 MVVGIVAAAA LCILILLYAM YKYRNRDEGS YQVDETRNYI SNSAQSNGTL MKEKQASSKS 1570 GHKKQKNKDK EYYV
	Isoform 3 (Alpha-1C) [UniParc]. Checksum: 35F97FD2C2C71884		1,572	173,410
	10 20 30 40 50 60 MSFTLHSVFF TLKVSSFLGS LVGLCLGLEF MGLPNQWARY LRWDASTRSD LSFQFKTNVS 70 80 90 100 110 120 TGLLLYLDDG GVCDFLCLSL VDGRVQLRFS MDCAETTVLS NKQVNDSSWH FLMVSRDRVR 130 140 150 160 170 180 TGLVIDGEGQ SGELRAQRPY MDVVSDLFLG GGPADIRPSA LTLDGVQNMP GFKGLMLDLK 190 200 210 220 230 240 YGNSEPRLLG SQSVQLEAEG PCGERPCENG GICFLLDGHP TCDCSTTGYG GTLCSEGLSH 250 260 270 280 290 300 LMMSEQGRSK AREENVATFR GSEYLSYDLS QNPIQSSSSE ITLSFKTWQR NGLILHTGKS 310 320 330 340 350 360 ADYVNLALKD GAVSLVINLG SGAFEAIVEP VNGKFNDNAW HDVKVTRNLR QVTISVDGIL 370 380 390 400 410 420 TTTGYTQEDY TMLGSDDSSY VGPSPSTADL PGSPVSNNFM GCLKEVVYKN NDIRLELSRL 430 440 450 460 470 480 ARIGATKMKI YGEVVFKCEN VATLDPINFE TPEAYISLPK WNTKRMGSIS FDFRTTEPNG 490 500 510 520 530 540 LILLTHGKPQ ERKDVRSQKN TKVDFFAVEL LDGNLYLLLD MGSGTIKVKA TQKKANDGEW 550 560 570 580 590 600 YHVDIQRDGR SGTISVNSRR TPFTASGQSE ILDLEGDMYL GGLPENRAGL ILPTELWTAM 610 620 630 640 650 660 LNYGYVGCIR DLFIDGRSKN IRQLAEMQNA AGVKSSCSRM SAKQCDSYPC KNNAVCKDGW 670 680 690 700 710 720 NRFICDCTGT GYWGRTCERE ASILSYDGSM YMKVIMPMVM HTEAEDVSFR FMSQRAYGLL 730 740 750 760 770 780 VATTSRDSAD TLRLELDGGR VKLMVNLDCI RINCNSSKGP ETLYAGQKLN DNEWHTVRVV 790 800 810 820 830 840 RRGKSLKLTV DDDVAEGTMV GDHTRLEFHN IETGIMTEKR YISVVPSSFI GHLQSLMFNG 850 860 870 880 890 900 LLYIDLCKNG DIDYCELKAR FGLRNIIADP VTFKTKSSYL TLATLQAYTS MHLFFQFKTT 910 920 930 940 950 960 SADGFILFNS GDGNNFIAVE LVKGYIHYVF DLGNGPNVIK GNSDRPLNDN QWHNVVITRD 970 980 990 1000 1010 1020 NSNTHSLKVD TKVVTQVING AKNLDLKGDL YMAGLAQGMY SNLPKLVASR DGFQGCLASV 1030 1040 1050 1060 1070 1080 DLNGRLPDLI NDALHRSGQI DRGCEGPSTT CQEDSCANQG VCMQQWEGFT CDCSMTSYSG 1090 1100 1110 1120 1130 1140 NQCNDPGATY IFGKSGGLIL YTWPANDRPS TRSDRLAVGF STTVKDGVLV RIDSAPGLGD 1150 1160 1170 1180 1190 1200 FLQLHIEQGK IGVVFNIGTV DISIKEERTP VNDGKYHVVR FTRNGANATL QVDNWPVNEH 1210 1220 1230 1240 1250 1260 YPTGNTDNER RQMVKQKIPF KYNRPVEEWL QEKGRQLTIF NTQAQIAIGG KDKGRLFQGQ 1270 1280 1290 1300 1310 1320 LSGLYYDGLK VLNMAAENNP NIKINGSVRL VGEVPSVSGT THTTSMPPEM STTVMETTTT 1330 1340 1350 1360 1370 1380 MATTTTRKNR STASIQPTSD DLVSSAECSS DDEDFVECEP STGRSDKSLS TSIFEGGYKA 1390 1400 1410 1420 1430 1440 HAPKWESKDF RPNKVSETSR TTTTSLSPEL IRFTASSSSG MVPKLPAGKM NNRDLKPQPD 1450 1460 1470 1480 1490 1500 IVLLPLPTAY ELDSTKLKSP LITCPMFRNV PTANPTEPGI RRVPGASEVI RESNSTTGMV 1510 1520 1530 1540 1550 1560 VGIVAAAALC ILILLYAMYK YRNRDEGSYQ VDETRNYISN SAQSNGTLMK EKQASSKSGH 1570 KKQKNKDKEY YV
	Isoform 4 (Alpha-1D) [UniParc]. Checksum: 86E13829189881D9		1,568	172,982
	10 20 30 40 50 60 MSFTLHSVFF TLKVSSFLGS LVGLCLGLEF MGLP