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Protein

Neurexin-3

Gene

Nrxn3

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Functioni

Neuronal cell surface protein that may be involved in cell recognition and cell adhesion. May mediate intracellular signaling.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi308CalciumBy similarity1
Metal bindingi325Calcium; via carbonyl oxygenBy similarity1
Metal bindingi378Calcium; via carbonyl oxygenBy similarity1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Cell adhesion

Keywords - Ligandi

Calcium, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Neurexin-3
Alternative name(s):
Neurexin III-alpha
Neurexin-3-alpha
Gene namesi
Name:Nrxn3
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Unplaced

Organism-specific databases

RGDi620212. Nrxn3.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini28 – 1503ExtracellularSequence analysisAdd BLAST1476
Transmembranei1504 – 1524HelicalSequence analysisAdd BLAST21
Topological domaini1525 – 1578CytoplasmicSequence analysisAdd BLAST54

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane, Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 271 PublicationAdd BLAST27
ChainiPRO_000001950028 – 1578Neurexin-3Add BLAST1551

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi58N-linked (GlcNAc...)Sequence analysis1
Glycosylationi105N-linked (GlcNAc...)Sequence analysis1
Disulfide bondi202 ↔ 213By similarity
Disulfide bondi207 ↔ 222By similarity
Disulfide bondi224 ↔ 234By similarity
Disulfide bondi408 ↔ 444By similarity
Disulfide bondi614 ↔ 643By similarity
Disulfide bondi651 ↔ 662By similarity
Disulfide bondi656 ↔ 671By similarity
Disulfide bondi673 ↔ 683By similarity
Glycosylationi761N-linked (GlcNAc...)Sequence analysis1
Disulfide bondi1022 ↔ 1050By similarity
Disulfide bondi1057 ↔ 1068By similarity
Disulfide bondi1062 ↔ 1077By similarity
Disulfide bondi1079 ↔ 1089By similarity
Glycosylationi1193N-linked (GlcNAc...)Sequence analysis1
Glycosylationi1291N-linked (GlcNAc...)Sequence analysis1
Glycosylationi1335N-linked (GlcNAc...)Sequence analysis1
Glycosylationi1500N-linked (GlcNAc...)Sequence analysis1

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

PRIDEiQ07310.

PTM databases

iPTMnetiQ07310.
PhosphoSitePlusiQ07310.

Expressioni

Tissue specificityi

Brain.

Interactioni

Subunit structurei

The laminin G-like domain 2 binds to NXPH1. Isoforms alpha 4B bind to alpha-dystroglycan. The cytoplasmic C-terminal region binds to CASK.3 Publications

Protein-protein interaction databases

BioGridi250475. 2 interactors.
IntActiQ07310. 1 interactor.
MINTiMINT-1538054.

Structurei

3D structure databases

ProteinModelPortaliQ07310.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini28 – 202Laminin G-like 1PROSITE-ProRule annotationAdd BLAST175
Domaini198 – 235EGF-like 1PROSITE-ProRule annotationAdd BLAST38
Domaini260 – 444Laminin G-like 2PROSITE-ProRule annotationAdd BLAST185
Domaini451 – 643Laminin G-like 3PROSITE-ProRule annotationAdd BLAST193
Domaini647 – 684EGF-like 2PROSITE-ProRule annotationAdd BLAST38
Domaini689 – 861Laminin G-like 4PROSITE-ProRule annotationAdd BLAST173
Domaini875 – 1050Laminin G-like 5PROSITE-ProRule annotationAdd BLAST176
Domaini1053 – 1090EGF-like 3PROSITE-ProRule annotationAdd BLAST38
Domaini1094 – 1294Laminin G-like 6PROSITE-ProRule annotationAdd BLAST201

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi282 – 285Poly-Ser4
Compositional biasi1323 – 1326Poly-Thr4
Compositional biasi1329 – 1332Poly-Thr4
Compositional biasi1407 – 1410Poly-Thr4
Compositional biasi1422 – 1425Poly-Ser4
Compositional biasi1511 – 1514Poly-Ala4

Sequence similaritiesi

Belongs to the neurexin family.Curated
Contains 3 EGF-like domains.PROSITE-ProRule annotation
Contains 6 laminin G-like domains.PROSITE-ProRule annotation

Keywords - Domaini

EGF-like domain, Repeat, Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

HOGENOMiHOG000230481.
HOVERGENiHBG052670.
InParanoidiQ07310.
KOiK07377.
PhylomeDBiQ07310.

Family and domain databases

Gene3Di2.60.120.200. 6 hits.
InterProiIPR013320. ConA-like_dom.
IPR000742. EGF-like_dom.
IPR000152. EGF-type_Asp/Asn_hydroxyl_site.
IPR001791. Laminin_G.
IPR003585. Neurexin-like.
IPR027158. NRXN3.
IPR027789. Syndecan/Neurexin_dom.
[Graphical view]
PANTHERiPTHR10127:SF405. PTHR10127:SF405. 3 hits.
PfamiPF00008. EGF. 1 hit.
PF02210. Laminin_G_2. 6 hits.
PF01034. Syndecan. 1 hit.
[Graphical view]
SMARTiSM00294. 4.1m. 1 hit.
SM00181. EGF. 3 hits.
SM00282. LamG. 6 hits.
[Graphical view]
SUPFAMiSSF49899. SSF49899. 7 hits.
PROSITEiPS00010. ASX_HYDROXYL. 1 hit.
PS50026. EGF_3. 3 hits.
PS50025. LAM_G_DOMAIN. 6 hits.
[Graphical view]

Sequences (19)i

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 19 isoformsi produced by alternative splicing. AlignAdd to basket

Note: There are five major alternatively spliced sites, each of which may be spliced in up to twelve different ways. Combinatorial splicing at each of these five sites may lead to the generation of at least 288 isoforms but for simplicity only individual splice events are explicitly described below. Isoforms Alpha 5A to isoform Alpha 5H lack the transmembrane domain. Experimental confirmation may be lacking for some isoforms.
Isoform 1 (identifier: Q07310-1) [UniParc]FASTAAdd to basket
Also known as: Alpha-5I

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MSFTLHSVFF TLKVSSFLGS LVGLCLGLEF MGLPNQWARY LRWDASTRSD
60 70 80 90 100
LSFQFKTNVS TGLLLYLDDG GVCDFLCLSL VDGRVQLRFS MDCAETTVLS
110 120 130 140 150
NKQVNDSSWH FLMVSRDRVR TGLVIDGEGQ SGELRAQRPY MDVVSDLFLG
160 170 180 190 200
GGPADIRPSA LTLDGVQNMP GFKGLMLDLK YGNSEPRLLG SQSVQLEAEG
210 220 230 240 250
PCGERPCENG GICFLLDGHP TCDCSTTGYG GTLCSEDVSQ GPGLSHLMMS
260 270 280 290 300
EQGRSKAREE NVATFRGSEY LSYDLSQNPI QSSSSEITLS FKTWQRNGLI
310 320 330 340 350
LHTGKSADYV NLALKDGAVS LVINLGSGAF EAIVEPVNGK FNDNAWHDVK
360 370 380 390 400
VTRNLRQVTI SVDGILTTTG YTQEDYTMLG SDDSSYVGPS PSTADLPGSP
410 420 430 440 450
VSNNFMGCLK EVVYKNNDIR LELSRLARIG ATKMKIYGEV VFKCENVATL
460 470 480 490 500
DPINFETPEA YISLPKWNTK RMGSISFDFR TTEPNGLILL THGKPQERKD
510 520 530 540 550
VRSQKNTKVD FFAVELLDGN LYLLLDMGSG TIKVKATQKK ANDGEWYHVD
560 570 580 590 600
IQRDGRSGTI SVNSRRTPFT ASGQSEILDL EGDMYLGGLP ENRAGLILPT
610 620 630 640 650
ELWTAMLNYG YVGCIRDLFI DGRSKNIRQL AEMQNAAGVK SSCSRMSAKQ
660 670 680 690 700
CDSYPCKNNA VCKDGWNRFI CDCTGTGYWG RTCEREASIL SYDGSMYMKV
710 720 730 740 750
IMPMVMHTEA EDVSFRFMSQ RAYGLLVATT SRDSADTLRL ELDGGRVKLM
760 770 780 790 800
VNLDCIRINC NSSKGPETLY AGQKLNDNEW HTVRVVRRGK SLKLTVDDDV
810 820 830 840 850
AEGTMVGDHT RLEFHNIETG IMTEKRYISV VPSSFIGHLQ SLMFNGLLYI
860 870 880 890 900
DLCKNGDIDY CELKARFGLR NIIADPVTFK TKSSYLTLAT LQAYTSMHLF
910 920 930 940 950
FQFKTTSADG FILFNSGDGN NFIAVELVKG YIHYVFDLGN GPNVIKGNSD
960 970 980 990 1000
RPLNDNQWHN VVITRDNSNT HSLKVDTKVV TQVINGAKNL DLKGDLYMAG
1010 1020 1030 1040 1050
LAQGMYSNLP KLVASRDGFQ GCLASVDLNG RLPDLINDAL HRSGQIDRGC
1060 1070 1080 1090 1100
EGPSTTCQED SCANQGVCMQ QWEGFTCDCS MTSYSGNQCN DPGATYIFGK
1110 1120 1130 1140 1150
SGGLILYTWP ANDRPSTRSD RLAVGFSTTV KDGVLVRIDS APGLGDFLQL
1160 1170 1180 1190 1200
HIEQGKIGVV FNIGTVDISI KEERTPVNDG KYHVVRFTRN GANATLQVDN
1210 1220 1230 1240 1250
WPVNEHYPTG NTDNERRQMV KQKIPFKYNR PVEEWLQEKG RQLTIFNTQA
1260 1270 1280 1290 1300
QIAIGGKDKG RLFQGQLSGL YYDGLKVLNM AAENNPNIKI NGSVRLVGEV
1310 1320 1330 1340 1350
PSVSGTTHTT SMPPEMSTTV METTTTMATT TTRKNRSTAS IQPTSDDLVS
1360 1370 1380 1390 1400
SAECSSDDED FVECEPSTGR SDKSLSTSIF EGGYKAHAPK WESKDFRPNK
1410 1420 1430 1440 1450
VSETSRTTTT SLSPELIRFT ASSSSGMVPK LPAGKMNNRD LKPQPDIVLL
1460 1470 1480 1490 1500
PLPTAYELDS TKLKSPLITC PMFRNVPTAN PTEPGIRRVP GASEVIRESN
1510 1520 1530 1540 1550
STTGMVVGIV AAAALCILIL LYAMYKYRNR DEGSYQVDET RNYISNSAQS
1560 1570
NGTLMKEKQA SSKSGHKKQK NKDKEYYV
Length:1,578
Mass (Da):173,994
Last modified:November 1, 1996 - v1
Checksum:i936CF8529143D0C7
GO
Isoform 2 (identifier: Q07310-2) [UniParc]FASTAAdd to basket
Also known as: Alpha-1B

The sequence of this isoform differs from the canonical sequence as follows:
     253-256: Missing.

Show »
Length:1,574
Mass (Da):173,565
Checksum:iA565F06AC79EBC8C
GO
Isoform 3 (identifier: Q07310-3) [UniParc]FASTAAdd to basket
Also known as: Alpha-1C

The sequence of this isoform differs from the canonical sequence as follows:
     237-242: Missing.

Show »
Length:1,572
Mass (Da):173,410
Checksum:i35F97FD2C2C71884
GO
Isoform 4 (identifier: Q07310-4) [UniParc]FASTAAdd to basket
Also known as: Alpha-1D

The sequence of this isoform differs from the canonical sequence as follows:
     237-242: Missing.
     253-256: Missing.

Show »
Length:1,568
Mass (Da):172,982
Checksum:i86E13829189881D9
GO
Isoform 5 (identifier: Q07310-5) [UniParc]FASTAAdd to basket
Also known as: Alpha-1E

The sequence of this isoform differs from the canonical sequence as follows:
     243-256: Missing.

Show »
Length:1,564
Mass (Da):172,451
Checksum:iD34F1E83B6B42035
GO
Isoform 6 (identifier: Q07310-6) [UniParc]FASTAAdd to basket
Also known as: Alpha-1F

The sequence of this isoform differs from the canonical sequence as follows:
     237-256: Missing.

Show »
Length:1,558
Mass (Da):171,867
Checksum:iA7AE5CCE2C75CE76
GO
Isoform 7 (identifier: Q07310-7) [UniParc]FASTAAdd to basket
Also known as: Alpha-3B

The sequence of this isoform differs from the canonical sequence as follows:
     754-763: DCIRINCNSS → G

Show »
Length:1,569
Mass (Da):172,945
Checksum:iB993492919356CC5
GO
Isoform 8 (identifier: Q07310-8) [UniParc]FASTAAdd to basket
Also known as: Alpha-4B

The sequence of this isoform differs from the canonical sequence as follows:
     1210-1239: Missing.

Show »
Length:1,548
Mass (Da):170,250
Checksum:i44A42D2AA6053D62
GO
Isoform 9 (identifier: Q07310-9) [UniParc]FASTAAdd to basket
Also known as: Alpha-5A

The sequence of this isoform differs from the canonical sequence as follows:
     1372-1478: Missing.
     1479-1578: ANPTEPGIRR...QKNKDKEYYV → ARSSNAARIT...LKFMCCHPPP

Show »
Length:1,438
Mass (Da):158,689
Checksum:i5DA4C69346C7FFF6
GO
Isoform 10 (identifier: Q07310-10) [UniParc]FASTAAdd to basket
Also known as: Alpha-5B

The sequence of this isoform differs from the canonical sequence as follows:
     1369-1371: Missing.
     1372-1478: Missing.
     1479-1578: ANPTEPGIRR...QKNKDKEYYV → ARSSNAARIT...LKFMCCHPPP

Show »
Length:1,435
Mass (Da):158,388
Checksum:i4DA00E05678DB01F
GO
Isoform 11 (identifier: Q07310-11) [UniParc]FASTAAdd to basket
Also known as: Alpha-5C

The sequence of this isoform differs from the canonical sequence as follows:
     1372-1478: Missing.
     1479-1578: ANPTEPGIRR...QKNKDKEYYV → VLERRIILNLKTNAHPKSLQSKTC

Show »
Length:1,395
Mass (Da):153,889
Checksum:iF51D7F30DADE9E49
GO
Isoform 12 (identifier: Q07310-12) [UniParc]FASTAAdd to basket
Also known as: Alpha-5D

The sequence of this isoform differs from the canonical sequence as follows:
     1369-1371: Missing.
     1372-1478: Missing.
     1479-1578: ANPTEPGIRR...QKNKDKEYYV → VLERRIILNLKTNAHPKSLQSKTC

Show »
Length:1,392
Mass (Da):153,589
Checksum:iF8D7669F3A237005
GO
Isoform 13 (identifier: Q07310-13) [UniParc]FASTAAdd to basket
Also known as: Alpha-5E

The sequence of this isoform differs from the canonical sequence as follows:
     1372-1478: Missing.
     1479-1578: ANPTEPGIRR...QKNKDKEYYV → DILLKSF

Show »
Length:1,378
Mass (Da):151,961
Checksum:iFB88CCC4F7199BCB
GO
Isoform 14 (identifier: Q07310-14) [UniParc]FASTAAdd to basket
Also known as: Alpha-5F

The sequence of this isoform differs from the canonical sequence as follows:
     1369-1371: Missing.
     1372-1478: Missing.
     1479-1578: ANPTEPGIRR...QKNKDKEYYV → DILLKSF

Show »
Length:1,375
Mass (Da):151,660
Checksum:iDA058AF65978461C
GO
Isoform 15 (identifier: Q07310-15) [UniParc]FASTAAdd to basket
Also known as: Alpha-5G

The sequence of this isoform differs from the canonical sequence as follows:
     1372-1478: Missing.
     1479-1578: ANPTEPGIRR...QKNKDKEYYV → ATTTTKKSNFQECGNSICPRAFLHNFLL

Show »
Length:1,399
Mass (Da):154,268
Checksum:iEAEE734DFC9B091A
GO
Isoform 16 (identifier: Q07310-16) [UniParc]FASTAAdd to basket
Also known as: Alpha-5H

The sequence of this isoform differs from the canonical sequence as follows:
     1369-1371: Missing.
     1372-1478: Missing.
     1479-1578: ANPTEPGIRR...QKNKDKEYYV → ATTTTKKSNFQECGNSICPRAFLHNFLL

Show »
Length:1,396
Mass (Da):153,968
Checksum:i687D090AB15110B5
GO
Isoform 17 (identifier: Q07310-17) [UniParc]FASTAAdd to basket
Also known as: Alpha-5J

The sequence of this isoform differs from the canonical sequence as follows:
     1369-1371: Missing.

Show »
Length:1,575
Mass (Da):173,693
Checksum:iBBAF52E01BDA3562
GO
Isoform 18 (identifier: Q07310-18) [UniParc]FASTAAdd to basket
Also known as: Alpha-5K

The sequence of this isoform differs from the canonical sequence as follows:
     1372-1478: Missing.

Show »
Length:1,471
Mass (Da):162,216
Checksum:iCB2D693F873094A1
GO
Isoform 19 (identifier: Q07310-19) [UniParc]FASTAAdd to basket
Also known as: Alpha-5L

The sequence of this isoform differs from the canonical sequence as follows:
     1369-1371: Missing.
     1372-1478: Missing.

Show »
Length:1,468
Mass (Da):161,916
Checksum:i5E3B919BD0323E7F
GO

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Alternative sequenceiVSP_003522237 – 256Missing in isoform 6. CuratedAdd BLAST20
Alternative sequenceiVSP_003521237 – 242Missing in isoform 3 and isoform 4. Curated6
Alternative sequenceiVSP_003523243 – 256Missing in isoform 5. CuratedAdd BLAST14
Alternative sequenceiVSP_003524253 – 256Missing in isoform 2 and isoform 4. Curated4
Alternative sequenceiVSP_003525754 – 763DCIRINCNSS → G in isoform 7. Curated10
Alternative sequenceiVSP_0035261210 – 1239Missing in isoform 8. CuratedAdd BLAST30
Alternative sequenceiVSP_0035271369 – 1371Missing in isoform 10, isoform 12, isoform 14, isoform 16, isoform 17 and isoform 19. Curated3
Alternative sequenceiVSP_0035281372 – 1478Missing in isoform 9, isoform 10, isoform 11, isoform 12, isoform 13, isoform 14, isoform 15, isoform 16, isoform 18 and isoform 19. CuratedAdd BLAST107
Alternative sequenceiVSP_0035301479 – 1578ANPTE…KEYYV → VLERRIILNLKTNAHPKSLQ SKTC in isoform 11 and isoform 12. CuratedAdd BLAST100
Alternative sequenceiVSP_0035311479 – 1578ANPTE…KEYYV → DILLKSF in isoform 13 and isoform 14. CuratedAdd BLAST100
Alternative sequenceiVSP_0035321479 – 1578ANPTE…KEYYV → ATTTTKKSNFQECGNSICPR AFLHNFLL in isoform 15 and isoform 16. CuratedAdd BLAST100
Alternative sequenceiVSP_0035291479 – 1578ANPTE…KEYYV → ARSSNAARITPCRPYMDMAT HLHIYPSHLHLLCSTLIDTP LPFPHPFFPMLPPSLALLKF MCCHPPP in isoform 9 and isoform 10. CuratedAdd BLAST100

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L14851 mRNA. Translation: AAA02853.1.
L14851 mRNA. Translation: AAA02854.1.
L14851 mRNA. Translation: AAA02855.1.
L14851 mRNA. Translation: AAA02856.1.
L14851 mRNA. Translation: AAA02857.1.
L14851 mRNA. Translation: AAA02858.1.
PIRiI48216.
RefSeqiNP_446269.2. NM_053817.2. [Q07310-1]
UniGeneiRn.10926.

Genome annotation databases

GeneIDi116508.
KEGGirno:116508.
UCSCiRGD:620212. rat. [Q07310-1]

Keywords - Coding sequence diversityi

Alternative splicing

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L14851 mRNA. Translation: AAA02853.1.
L14851 mRNA. Translation: AAA02854.1.
L14851 mRNA. Translation: AAA02855.1.
L14851 mRNA. Translation: AAA02856.1.
L14851 mRNA. Translation: AAA02857.1.
L14851 mRNA. Translation: AAA02858.1.
PIRiI48216.
RefSeqiNP_446269.2. NM_053817.2. [Q07310-1]
UniGeneiRn.10926.

3D structure databases

ProteinModelPortaliQ07310.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi250475. 2 interactors.
IntActiQ07310. 1 interactor.
MINTiMINT-1538054.

PTM databases

iPTMnetiQ07310.
PhosphoSitePlusiQ07310.

Proteomic databases

PRIDEiQ07310.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi116508.
KEGGirno:116508.
UCSCiRGD:620212. rat. [Q07310-1]

Organism-specific databases

CTDi9369.
RGDi620212. Nrxn3.

Phylogenomic databases

HOGENOMiHOG000230481.
HOVERGENiHBG052670.
InParanoidiQ07310.
KOiK07377.
PhylomeDBiQ07310.

Family and domain databases

Gene3Di2.60.120.200. 6 hits.
InterProiIPR013320. ConA-like_dom.
IPR000742. EGF-like_dom.
IPR000152. EGF-type_Asp/Asn_hydroxyl_site.
IPR001791. Laminin_G.
IPR003585. Neurexin-like.
IPR027158. NRXN3.
IPR027789. Syndecan/Neurexin_dom.
[Graphical view]
PANTHERiPTHR10127:SF405. PTHR10127:SF405. 3 hits.
PfamiPF00008. EGF. 1 hit.
PF02210. Laminin_G_2. 6 hits.
PF01034. Syndecan. 1 hit.
[Graphical view]
SMARTiSM00294. 4.1m. 1 hit.
SM00181. EGF. 3 hits.
SM00282. LamG. 6 hits.
[Graphical view]
SUPFAMiSSF49899. SSF49899. 7 hits.
PROSITEiPS00010. ASX_HYDROXYL. 1 hit.
PS50026. EGF_3. 3 hits.
PS50025. LAM_G_DOMAIN. 6 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiNRX3A_RAT
AccessioniPrimary (citable) accession number: Q07310
Secondary accession number(s): Q07280
, Q07311, Q07312, Q07313, Q07314
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 16, 2001
Last sequence update: November 1, 1996
Last modified: November 2, 2016
This is version 145 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.