ID   ADH1_ZEALU              Reviewed;         293 AA.
AC   Q07264;
DT   01-FEB-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1996, sequence version 2.
DT   16-JUN-2009, entry version 59.
DE   RecName: Full=Alcohol dehydrogenase 1;
DE            EC=1.1.1.1;
DE   Flags: Fragment;
GN   Name=ADH1;
OS   Zea luxurians (Guatemalan teosinte).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliophyta; Liliopsida; Poales; Poaceae;
OC   PACCAD clade; Panicoideae; Andropogoneae; Zea.
OX   NCBI_TaxID=15945;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   MEDLINE=93281703; PubMed=8506356; DOI=10.1073/pnas.90.11.5095;
RA   Gaut B.S., Clegg M.T.;
RT   "Molecular evolution of the Adh1 locus in the genus Zea.";
RL   Proc. Natl. Acad. Sci. U.S.A. 90:5095-5099(1993).
CC   -!- CATALYTIC ACTIVITY: An alcohol + NAD(+) = an aldehyde or ketone +
CC       NADH.
CC   -!- COFACTOR: Binds 2 zinc ions per subunit (By similarity).
CC   -!- SUBUNIT: Homodimer.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm.
CC   -!- SIMILARITY: Belongs to the zinc-containing alcohol dehydrogenase
CC       family.
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DR   EMBL; L08588; AAA74639.1; -; Genomic_DNA.
DR   EMBL; L08590; AAA74641.1; -; Genomic_DNA.
DR   UniGene; Zm.1540; -.
DR   HSSP; P11766; 1M6H.
DR   Gramene; Q07264; -.
DR   BRENDA; 1.1.1.1; 312134.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0004022; F:alcohol dehydrogenase activity; IEA:EC.
DR   GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0055114; P:oxidation reduction; IEA:UniProtKB-KW.
DR   InterPro; IPR013154; ADH_GroES-like.
DR   InterPro; IPR002085; ADH_SF_Zn.
DR   InterPro; IPR013149; ADH_Zn-bd.
DR   InterPro; IPR002328; ADH_Zn_CS.
DR   InterPro; IPR016040; NAD(P)-bd_dom.
DR   Gene3D; G3DSA:3.40.50.720; NAD(P)-bd; 1.
DR   PANTHER; PTHR11695; ADH_Sf_Zn; 1.
DR   Pfam; PF08240; ADH_N; 1.
DR   Pfam; PF00107; ADH_zinc_N; 1.
DR   PROSITE; PS00059; ADH_ZINC; PARTIAL.
PE   3: Inferred from homology;
KW   Cytoplasm; Metal-binding; NAD; Oxidoreductase; Zinc.
FT   CHAIN        <1   >293       Alcohol dehydrogenase 1.
FT                                /FTId=PRO_0000160704.
FT   NP_BIND     129    134       NAD (By similarity).
FT   NP_BIND     222    224       NAD (By similarity).
FT   METAL        26     26       Zinc 2 (By similarity).
FT   METAL        29     29       Zinc 2 (By similarity).
FT   METAL        32     32       Zinc 2 (By similarity).
FT   METAL        40     40       Zinc 2 (By similarity).
FT   METAL       104    104       Zinc 1; catalytic (By similarity).
FT   BINDING     153    153       NAD (By similarity).
FT   BINDING     158    158       NAD (By similarity).
FT   NON_TER       1      1
FT   NON_TER     293    293
SQ   SEQUENCE   293 AA;  31490 MW;  E1B343AE6EF9CBD4 CRC64;
     IIESVGEGVT DVAPGDHVLP VFTGECKECA HCKSAESNMC DLLRINTDRG VMIGDGKSRF
     SINGKPIYHF VGTSTFSEYT VMHVGCVAKI NPQAPLDKVC VLSCGISTGL GASINVAKPP
     KGSTVAVFGL GAVGLAAAEG ARIAGASRII GVDLNPSRFE EARKFGCTEF VNPKDHNKPV
     QEVLAEMTNG GVDRSVECTG NINAMIQAFE CVHDGWGVAV LVGVPHKDAE FKTHPMNFLN
     ERTLKGTFFG NYKPRTDLPN VVELYMKKEL EVEKFITHSV PFAEINKAFD LMA
//