Skip Header

 
Contribute Send feedback

Reviewed, UniProtKB/Swiss-Prot Q07264 (ADH1_ZEALU)

Last modified November 25, 2008. Version 54. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Alcohol dehydrogenase 1
    EC=1.1.1.1
Gene names
Name: ADH1
OrganismZea luxurians (Guatemalan teosinte)
Taxonomic identifier15945 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaePACCAD cladePanicoideaeAndropogoneaeZea

Protein attributes

Sequence length293 AA.
Sequence statusFragment.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

General annotation (Comments)

Catalytic activity

An alcohol + NAD(+) = an aldehyde or ketone + NADH.

Cofactor

Binds 2 zinc ions per subunit By similarity.

Subunit structure

Homodimer.

Subcellular location

Cytoplasm.

Sequence similarities

Belongs to the zinc-containing alcohol dehydrogenase family.

Ontologies

Keywords

   Cellular componentCytoplasm
   LigandMetal-binding
NAD
Zinc
   Molecular functionOxidoreductase

Gene Ontology (GO)

   Biological processoxidation reduction

Inferred from electronic annotation. Source: InterPro

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functionalcohol dehydrogenase activity

Inferred from electronic annotation. Source: EC

zinc ion binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain‹1 – ›293›293Alcohol dehydrogenase 1
PRO_0000160704

Sites

Metal binding261Zinc 2 By similarity
Metal binding291Zinc 2 By similarity
Metal binding321Zinc 2 By similarity
Metal binding401Zinc 2 By similarity
Metal binding1041Zinc 1; catalytic By similarity

Experimental info

Non-terminal residue11
Non-terminal residue2931

Sequences

Sequence LengthMass (Da)Tools
Q07264-1 [UniParc].

Last modified February 1, 1996. Version 2.
Checksum: E1B343AE6EF9CBD4

FASTA29331,490
        10         20         30         40         50         60 
IIESVGEGVT DVAPGDHVLP VFTGECKECA HCKSAESNMC DLLRINTDRG VMIGDGKSRF 

        70         80         90        100        110        120 
SINGKPIYHF VGTSTFSEYT VMHVGCVAKI NPQAPLDKVC VLSCGISTGL GASINVAKPP 

       130        140        150        160        170        180 
KGSTVAVFGL GAVGLAAAEG ARIAGASRII GVDLNPSRFE EARKFGCTEF VNPKDHNKPV 

       190        200        210        220        230        240 
QEVLAEMTNG GVDRSVECTG NINAMIQAFE CVHDGWGVAV LVGVPHKDAE FKTHPMNFLN 

       250        260        270        280        290 
ERTLKGTFFG NYKPRTDLPN VVELYMKKEL EVEKFITHSV PFAEINKAFD LMA 

« Hide

References

[1]"Molecular evolution of the Adh1 locus in the genus Zea."
Gaut B.S., Clegg M.T.
Proc. Natl. Acad. Sci. U.S.A. 90:5095-5099(1993) [PubMed: 8506356] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Cross-references

Sequence databases

L08588 Genomic DNA. Translation: AAA74639.1.
L08590 Genomic DNA. Translation: AAA74641.1.
UniGeneZm.1540
Zm.67805
Zm.93880

3D structure databases

HSSPHSSP built from PDB template 1M6H based on UniProtKB P11766.
ModBaseSearch...

Organism-specific databases

GrameneQ07264.

Family and domain databases

InterProIPR013154. AlcDHase_GroES-like.
IPR002085. AlcDHase_SF_Zn.
IPR013149. AlcDHase_Zn-bd.
IPR002328. AlcDHase_Zn_CS.
IPR016040. NAD(P)-bd.
[Graphical view]
Gene3DG3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
PANTHERPTHR11695. ADH_Sf_Zn. 1 hit.
PfamPF08240. ADH_N. 1 hit.
PF00107. ADH_zinc_N. 1 hit.
[Graphical view]
PROSITEPS00059. ADH_ZINC. Partial match.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameADH1_ZEALU
AccessionPrimary (citable) accession number: Q07264
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: February 1, 1996
Last modified: November 25, 2008
This is version 54 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectPPAP (Plant Proteome Annotation Project)

Relevant documents

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents