Q07259 (TRG_CUPNH) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Putative transglycosylase H16_A0665
EC=2.4.2.-

Gene names

Ordered Locus Names:

H16_A0665

Organism

Cupriavidus necator (strain ATCC 17699 / H16 / DSM 428 / Stanier 337) (Ralstonia eutropha) [Complete proteome] [HAMAP]

Taxonomic identifier

381666 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Cupriavidus

Protein attributes

Sequence length	231 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Cell wall formation.
Pathway	Cell wall biogenesis; peptidoglycan biosynthesis.
Subcellular location	Secreted. Membrane Potential. Note: Membrane-associated Potential.
Sequence similarities	Belongs to the glycosyltransferase 51 family.

Ontologies

Keywords
Biological process	Cell shape Cell wall biogenesis/degradation Peptidoglycan synthesis
Cellular component	Membrane Secreted
Domain	Transmembrane Transmembrane helix
Molecular function	Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	cellular cell wall organization Inferred from electronic annotation. Source: UniProtKB-KW peptidoglycan biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW regulation of cell shape Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	extracellular region Inferred from electronic annotation. Source: UniProtKB-SubCell integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW peptidoglycan-based cell wall Inferred from electronic annotation. Source: InterPro
Molecular function	transferase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 231	231	Putative transglycosylase H16_A0665		PRO_0000083163
Regions
	Transmembrane	8 – 28	21	Helical; Potential
Experimental info
	Sequence conflict	183	1	P → G in CAA80433. Ref.2

Sequences

	Sequence		Length	Mass (Da)
	Q07259 [UniParc]. Last modified January 23, 2007. Version 2. Checksum: 88A2480299341D92	FASTA	231	25,806
	10 20 30 40 50 60 MKRLWSAFIK LLVLAVIGGA LLAAIAILAA NRQLPSLDAL TAFRHTPDYV PIGKIPRELT 70 80 90 100 110 120 GAVVAIEDER FYVHDGIDYI GVVRAGVANL SDELSQGAST ITMQVARNFY LSRDKTYTRK 130 140 150 160 170 180 LYEVLLSYRI EKALTKDEIL ELYMNKIYLG QGAYGFADAA RTYFGKRLDQ LTLAECAMLA 190 200 210 220 230 GLPKAPSANN PVANPRRARQ RQVYILQRML ELGRISRGEY DGALLEPLRL R

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Genome sequence of the bioplastic-producing 'Knallgas' bacterium Ralstonia eutropha H16." Pohlmann A., Fricke W.F., Reinecke F., Kusian B., Liesegang H., Cramm R., Eitinger T., Ewering C., Poetter M., Schwartz E., Strittmatter A., Voss I., Gottschalk G., Steinbuechel A., Friedrich B., Bowien B. Nat. Biotechnol. 24:1257-1262(2006) [PubMed: 16964242] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 17699 / H16 / DSM 428 / Stanier 337.
[2]	"The Alcaligenes eutrophus ldh structural gene encodes a novel type of lactate dehydrogenase." Jendrossek D., Kratzin H.D., Steinbuechel A. FEMS Microbiol. Lett. 112:229-235(1993) [PubMed: 8405966] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-207.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AM260479 Genomic DNA. Translation: CAJ91813.1. Z22737 Genomic DNA. Translation: CAA80433.1.
PIR	I39536.
RefSeq	YP_725181.1. NC_008313.1.
3D structure databases
ProteinModelPortal	Q07259.
ModBase	Search...
Protein-protein interaction databases
STRING	Q07259.
Protein family/group databases
CAZy	GT51. Glycosyltransferase Family 51.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4247613.
GenomeReviews	Gene locus H16_A0665 in contig AM260479_GR.
KEGG	reh:H16_A0665.
PATRIC	35230729. VBIRalEut6770_1033.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG5009.
HOGENOM	HBG685698.
OMA	DERFYVH.
ProtClustDB	CLSK939293.
Enzyme and pathway databases
BioCyc	REUT381666:H16_A0665-MONOMER.
Family and domain databases
InterPro	IPR001264. Glyco_trans_51. [Graphical view]
Pfam	PF00912. Transgly. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

TRG_CUPNH

Accession

Primary (citable) accession number: Q07259
Secondary accession number(s): Q0KDV8

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 1, 1995
Last sequence update:	January 23, 2007
Last modified:	January 25, 2012
This is version 78 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program