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Q07159

- ALF1_STACT

UniProt

Q07159 - ALF1_STACT

Protein

Fructose-bisphosphate aldolase class 1

Gene

fda

Organism
Staphylococcus carnosus (strain TM300)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 86 (01 Oct 2014)
      Sequence version 3 (23 Jan 2007)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    D-fructose 1,6-bisphosphate = glycerone phosphate + D-glyceraldehyde 3-phosphate.

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei175 – 1751Proton acceptorBy similarity
    Active sitei212 – 2121Schiff-base intermediate with dihydroxyacetone-PBy similarity

    GO - Molecular functioni

    1. fructose-bisphosphate aldolase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. glycolytic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Lyase

    Keywords - Biological processi

    Glycolysis

    Keywords - Ligandi

    Schiff base

    Enzyme and pathway databases

    BioCyciSCAR396513:GJ9G-2205-MONOMER.
    UniPathwayiUPA00109; UER00183.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Fructose-bisphosphate aldolase class 1 (EC:4.1.2.13)
    Alternative name(s):
    Fructose-bisphosphate aldolase class I
    Short name:
    FBP aldolase
    Gene namesi
    Name:fda
    Ordered Locus Names:Sca_2144
    OrganismiStaphylococcus carnosus (strain TM300)
    Taxonomic identifieri396513 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcus
    ProteomesiUP000000444: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Initiator methioninei1 – 11Removed1 Publication
    Chaini2 – 296295Fructose-bisphosphate aldolase class 1PRO_0000216909Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi396513.Sca_2144.

    Structurei

    3D structure databases

    ProteinModelPortaliQ07159.
    SMRiQ07159. Positions 1-294.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Phylogenomic databases

    eggNOGiCOG3588.
    HOGENOMiHOG000073502.
    KOiK01623.
    OMAiYTGDYLA.
    OrthoDBiEOG6M6JJT.

    Family and domain databases

    Gene3Di3.20.20.70. 1 hit.
    HAMAPiMF_00729. FBP_aldolase_1.
    InterProiIPR013785. Aldolase_TIM.
    IPR000741. FBA_I.
    IPR023014. FBA_I_Gram+-type.
    [Graphical view]
    PfamiPF00274. Glycolytic. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    Q07159-1 [UniParc]FASTAAdd to Basket

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    MNQEQFDKIK NGKGFIAALD QSGGSTPKAL KDYGVEENEY SNDEEMFNLV    50
    HDMRTRIITS PAFNGEKILG AILFEQTMDR EVEGKYTGSY LADKGIVPFL 100
    KVDKGLAEEA DGVQLMKPIP DLDKLLDRAN ERGIFGTKMR SNILENNKEA 150
    IEKVVKQQFE VAKEIIAAGL VPIIEPEVNI NAKDKEAIEA NLAEAIKAEL 200
    DNLKKDQYVM LKLTIPTKVN AYSELIEHPQ VIRVVALSGG YSRDEANKIL 250
    KQNDGLIASF SRALVSDLNA QQSDAEFNEK LQEAIDTIFD ASVNKA 296
    Length:296
    Mass (Da):32,851
    Last modified:January 23, 2007 - v3
    Checksum:i13B5033BE67BF7E9
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X71729 Genomic DNA. Translation: CAA50663.1.
    AM295250 Genomic DNA. Translation: CAL29049.1.
    PIRiA49943.
    RefSeqiWP_015901385.1. NC_012121.1.
    YP_002635234.1. NC_012121.1.

    Genome annotation databases

    GeneIDi7551079.
    KEGGisca:Sca_2144.
    PATRICi19605162. VBIStaCar105558_2143.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X71729 Genomic DNA. Translation: CAA50663.1 .
    AM295250 Genomic DNA. Translation: CAL29049.1 .
    PIRi A49943.
    RefSeqi WP_015901385.1. NC_012121.1.
    YP_002635234.1. NC_012121.1.

    3D structure databases

    ProteinModelPortali Q07159.
    SMRi Q07159. Positions 1-294.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 396513.Sca_2144.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 7551079.
    KEGGi sca:Sca_2144.
    PATRICi 19605162. VBIStaCar105558_2143.

    Phylogenomic databases

    eggNOGi COG3588.
    HOGENOMi HOG000073502.
    KOi K01623.
    OMAi YTGDYLA.
    OrthoDBi EOG6M6JJT.

    Enzyme and pathway databases

    UniPathwayi UPA00109 ; UER00183 .
    BioCyci SCAR396513:GJ9G-2205-MONOMER.

    Family and domain databases

    Gene3Di 3.20.20.70. 1 hit.
    HAMAPi MF_00729. FBP_aldolase_1.
    InterProi IPR013785. Aldolase_TIM.
    IPR000741. FBA_I.
    IPR023014. FBA_I_Gram+-type.
    [Graphical view ]
    Pfami PF00274. Glycolytic. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Cloning, sequencing, and characterization of the gene encoding the class I fructose-1,6-bisphosphate aldolase of Staphylococcus carnosus."
      Witke C., Goetz F.
      J. Bacteriol. 175:7495-7499(1993) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], PROTEIN SEQUENCE OF 2-8.
    2. "Genome analysis of the meat starter culture bacterium Staphylococcus carnosus TM300."
      Rosenstein R., Nerz C., Biswas L., Resch A., Raddatz G., Schuster S.C., Goetz F.
      Appl. Environ. Microbiol. 75:811-822(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: TM300.

    Entry informationi

    Entry nameiALF1_STACT
    AccessioniPrimary (citable) accession number: Q07159
    Secondary accession number(s): B9DJW7
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 1, 1994
    Last sequence update: January 23, 2007
    Last modified: October 1, 2014
    This is version 86 of the entry and version 3 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Direct protein sequencing, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3