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Q07113

- MPRI_MOUSE

UniProt

Q07113 - MPRI_MOUSE

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Protein
Cation-independent mannose-6-phosphate receptor
Gene
Igf2r
Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 5 out of 5 - Experimental evidence at protein leveli

Functioni

Acts as a positive regulator of T-cell coactivation, by binding DPP4 By similarity. Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex. This receptor also binds IGF2.

GO - Molecular functioni

  1. G-protein coupled receptor activity Source: Ensembl
  2. glycoprotein binding Source: UniProtKB
  3. insulin-like growth factor binding Source: MGI
  4. mannose binding Source: MGI
  5. phosphoprotein binding Source: UniProtKB
  6. retinoic acid binding Source: Ensembl
  7. transporter activity Source: InterPro
Complete GO annotation...

GO - Biological processi

  1. liver development Source: Ensembl
  2. organ regeneration Source: Ensembl
  3. positive regulation of apoptotic process Source: Ensembl
  4. post-embryonic development Source: Ensembl
  5. response to retinoic acid Source: Ensembl
  6. spermatogenesis Source: Ensembl
Complete GO annotation...

Keywords - Molecular functioni

Receptor

Keywords - Biological processi

Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Cation-independent mannose-6-phosphate receptor
Short name:
CI Man-6-P receptor
Short name:
CI-MPR
Short name:
M6PR
Alternative name(s):
300 kDa mannose 6-phosphate receptor
Short name:
MPR 300
Insulin-like growth factor 2 receptor
Insulin-like growth factor II receptor
Short name:
IGF-II receptor
M6P/IGF2 receptor
Short name:
M6P/IGF2R
CD_antigen: CD222
Gene namesi
Name:Igf2r
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 17

Organism-specific databases

MGIiMGI:96435. Igf2r.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini36 – 22952260Lumenal Reviewed prediction
Add
BLAST
Transmembranei2296 – 231621Helical; Reviewed prediction
Add
BLAST
Topological domaini2317 – 2483167Cytoplasmic Reviewed prediction
Add
BLAST

GO - Cellular componenti

  1. cell surface Source: UniProtKB
  2. clathrin coat Source: Ensembl
  3. endocytic vesicle Source: UniProtKB
  4. endosome Source: MGI
  5. extracellular space Source: Ensembl
  6. integral component of membrane Source: UniProtKB-KW
  7. late endosome Source: Ensembl
  8. lysosomal membrane Source: UniProtKB-SubCell
  9. membrane Source: MGI
  10. nuclear envelope lumen Source: MGI
  11. nucleus Source: MGI
  12. perinuclear region of cytoplasm Source: Ensembl
  13. plasma membrane Source: Ensembl
  14. trans-Golgi network transport vesicle Source: MGI
Complete GO annotation...

Keywords - Cellular componenti

Lysosome, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 3535 Reviewed prediction
Add
BLAST
Chaini36 – 24832448Cation-independent mannose-6-phosphate receptor
PRO_0000019230Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi44 ↔ 64 By similarity
Disulfide bondi72 ↔ 79 By similarity
Glycosylationi107 – 1071N-linked (GlcNAc...) Reviewed prediction
Disulfide bondi112 ↔ 144 By similarity
Disulfide bondi129 ↔ 156 By similarity
Disulfide bondi169 ↔ 207 By similarity
Disulfide bondi223 ↔ 230 By similarity
Disulfide bondi270 ↔ 301 By similarity
Disulfide bondi283 ↔ 313 By similarity
Disulfide bondi323 ↔ 361 By similarity
Disulfide bondi369 ↔ 377 By similarity
Glycosylationi395 – 3951N-linked (GlcNAc...) Reviewed prediction
Disulfide bondi415 ↔ 449 By similarity
Disulfide bondi429 ↔ 461 By similarity
Glycosylationi430 – 4301N-linked (GlcNAc...) Reviewed prediction
Glycosylationi537 – 5371N-linked (GlcNAc...) Reviewed prediction
Glycosylationi575 – 5751N-linked (GlcNAc...) Reviewed prediction
Glycosylationi620 – 6201N-linked (GlcNAc...) Reviewed prediction
Disulfide bondi621 ↔ 658 By similarity
Disulfide bondi666 ↔ 673 By similarity
Disulfide bondi724 ↔ 753 By similarity
Glycosylationi740 – 7401N-linked (GlcNAc...)1 Publication
Glycosylationi864 – 8641N-linked (GlcNAc...) Reviewed prediction
Glycosylationi944 – 9441N-linked (GlcNAc...) Reviewed prediction
Glycosylationi1157 – 11571N-linked (GlcNAc...) Reviewed prediction
Glycosylationi1239 – 12391N-linked (GlcNAc...) Reviewed prediction
Glycosylationi1305 – 13051N-linked (GlcNAc...) Reviewed prediction
Glycosylationi1358 – 13581N-linked (GlcNAc...) Reviewed prediction
Glycosylationi1423 – 14231N-linked (GlcNAc...) Reviewed prediction
Disulfide bondi1509 ↔ 1546 By similarity
Glycosylationi1532 – 15321N-linked (GlcNAc...)2 Publications
Disulfide bondi1552 ↔ 1559 By similarity
Disulfide bondi1591 ↔ 1627 By similarity
Disulfide bondi1607 ↔ 1639 By similarity
Disulfide bondi1645 ↔ 1688 By similarity
Glycosylationi1649 – 16491N-linked (GlcNAc...) Reviewed prediction
Disulfide bondi1699 ↔ 1706 By similarity
Disulfide bondi1743 ↔ 1776 By similarity
Glycosylationi1750 – 17501N-linked (GlcNAc...)1 Publication
Disulfide bondi1759 ↔ 1788 By similarity
Disulfide bondi1797 ↔ 1832 By similarity
Glycosylationi1809 – 18091N-linked (GlcNAc...) Reviewed prediction
Disulfide bondi1843 ↔ 1849 By similarity
Disulfide bondi1886 ↔ 1968 By similarity
Disulfide bondi1896 ↔ 1920 By similarity
Disulfide bondi1910 ↔ 1935 By similarity
Disulfide bondi1950 ↔ 1980 By similarity
Disulfide bondi1987 ↔ 2022 By similarity
Disulfide bondi2032 ↔ 2039 By similarity
Disulfide bondi2075 ↔ 2106 By similarity
Glycosylationi2078 – 20781N-linked (GlcNAc...) Reviewed prediction
Disulfide bondi2089 ↔ 2118 By similarity
Glycosylationi2129 – 21291N-linked (GlcNAc...) Reviewed prediction
Modified residuei2342 – 23421N6-acetyllysine By similarity
Modified residuei2401 – 24011Phosphoserine2 Publications
Modified residuei2471 – 24711Phosphoserine1 Publication
Modified residuei2476 – 24761Phosphoserine4 Publications

Keywords - PTMi

Acetylation, Disulfide bond, Glycoprotein, Phosphoprotein

Proteomic databases

MaxQBiQ07113.
PaxDbiQ07113.
PRIDEiQ07113.

PTM databases

PhosphoSiteiQ07113.

Expressioni

Gene expression databases

ArrayExpressiQ07113.
BgeeiQ07113.
CleanExiMM_IGF2R.
GenevestigatoriQ07113.

Interactioni

Subunit structurei

Interacts with DPP4; the interaction is direct. Binds GGA1, GGA2 and GGA3. Binds HA-I and HA-II plasma membrane adapters By similarity.

Protein-protein interaction databases

BioGridi200550. 1 interaction.
IntActiQ07113. 4 interactions.
MINTiMINT-200350.

Structurei

3D structure databases

ProteinModelPortaliQ07113.
SMRiQ07113. Positions 43-2159.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Repeati35 – 1841501
Add
BLAST
Repeati185 – 3391552
Add
BLAST
Repeati340 – 4841453
Add
BLAST
Repeati485 – 6371534
Add
BLAST
Repeati638 – 7761395
Add
BLAST
Repeati777 – 9431676
Add
BLAST
Repeati945 – 10921487
Add
BLAST
Repeati1093 – 12361448
Add
BLAST
Repeati1237 – 13771419
Add
BLAST
Repeati1378 – 152514810
Add
BLAST
Repeati1526 – 165913411
Add
BLAST
Repeati1660 – 181315412
Add
BLAST
Repeati1814 – 200118813
Add
BLAST
Domaini1891 – 193747Fibronectin type-II
Add
BLAST
Repeati2002 – 213012914
Add
BLAST
Repeati2158 – 228212515
Add
BLAST

Domaini

Sequence similaritiesi

Belongs to the MRL1/IGF2R family.

Keywords - Domaini

Repeat, Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiNOG260109.
GeneTreeiENSGT00390000013943.
HOGENOMiHOG000113638.
HOVERGENiHBG000334.
InParanoidiQ07113.
KOiK06564.
OMAiVDCQVTD.
OrthoDBiEOG74BJRG.
PhylomeDBiQ07113.
TreeFamiTF328963.

Family and domain databases

Gene3Di2.10.10.10. 1 hit.
2.70.130.10. 16 hits.
InterProiIPR000479. CIMR.
IPR000562. FN_type2_col-bd.
IPR013806. Kringle-like.
IPR009011. Man6P_isomerase_rcpt-bd_dom.
[Graphical view]
PfamiPF00878. CIMR. 14 hits.
PF00040. fn2. 1 hit.
[Graphical view]
SMARTiSM00059. FN2. 1 hit.
[Graphical view]
SUPFAMiSSF50911. SSF50911. 16 hits.
SSF57440. SSF57440. 1 hit.
PROSITEiPS00023. FN2_1. 1 hit.
PS51092. FN2_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q07113-1 [UniParc]FASTAAdd to Basket

« Hide

MRAVQLGPVP SGPRVALLPP LLLLLLLAAA GSAQAQAVDL DALCSYTWEA     50
VDSKNNAVYK INVCGNVGIS SCGPTSAICM CDLKTENCRS VGDSLLRSSA 100
RSLLEFNTTM GCQPSDSQHR IQTSITFLCG KTLGTPEFVT ATDCVHYFEW 150
RTTAACKKDI FKADKEVPCY AFDDKLQKHD LNPLIKLNGG YLVDDSDPDT 200
SLFINVCRDI DSLRDPSTQL RVCPAGTAAC LLKGNQAFDV GRPKEGLKLL 250
SKDRLVLTYV KEEGEKPDFC NGHSPAVTVT FVCPSERREG TIPKLTAKSN 300
CRYEVEWITE YACHRDYLQS ESCSLSSEQH DITIDLSPLA QYGGSPYVSD 350
GREYTFFINV CGDTKVSLCN NKEAAVCQEK KADSTQVKIA GRHQNQTLRY 400
SDGDLTLIYS GGDECSSGFQ RMSVINFECN KTAGKDGRGE PVFTGEVDCT 450
YFFTWDTKYA CIKEKEDLLC GAINGKKRYD LSVLARHSES EQNWEAVDGS 500
QAESEKYFFI NVCHRVLQEG KARNCPEDAA VCAVDKNGSK NLGKFVSSPT 550
KEKGHIQLSY TDGDDCGSDK KISTNITLVC KPGDLESAPV LRAARSDGCF 600
YEFEWHTAAA CVLSKTEGEN CTVLDAQAGF SFDLSLLTKK NGAYKVETEK 650
YDFYINVCGP VSMDPCQSNS GACQVAKSGK SWNLGLSSTK LTYYDGMIQL 700
SYRNGTPYNN EKHTPRATLI TFLCDRDAGV GFPEYQEEDN STYNFRWYTS 750
YACPEEPLEC MVTDPSMMEQ YDLSSLVKSE GGSGGNWYAM ENSREHVTRR 800
KYYLNVCRPL NPVPGCDRYA SACQMKYENH EGSLAETVSI SNLGVAKIGP 850
VVEESGSLLL EYVNGSACTT SDGQLTTYST RIHLVCGRGF MNSHPIFTFN 900
WECVVSFLWN TEAACPIQTI TETDQACSIR DPSSGFVFNL SPLNDSAQGH 950
VVLGIGKTFV FNICGAMPAC GTVAGKPAYG CEAETQIEDI KDLRPQRPVG 1000
MERSLQLSAE GFLTLTYKGS SPSDRGTAFI IRFICNDDIY PGAPKFLHQD 1050
IDSTRGIRNT YFEFETALAC TPSLVDCQVT DPAGNEYDLS ALSMVRKPWT 1100
AVDTSAYGKR RHFYLSVCNP LPYIPGCHGI ALGSCMVSED NSFNLGVVQI 1150
SPQATGNGSL SILYVNGDRC GDQRFSTRIV FECAQTSGSP MFQFVNNCEY 1200
VFVWRTVEAC PVIREEGDNC QVKDPRHGNL YDLKPLGLND TIVSVGEYTY 1250
YLRVCGKLSS DVCSAHDGSK AVSSCQEKKG PQGFQKVAGL LSQKLTFENG 1300
LLKMNYTGGD TCHKVYQRST TIYFYCDRTT QKPVFLKETS DCSYMFEWRT 1350
QYACPPFNVT ECSVQDAAGN SIDLSSLSRY SDNWEAVTRT GATEHYLINV 1400
CKSLSPHAGT EPCPPEAAVC LLNGSKPVNL GKVRDGPQWT DGVTVLQYVD 1450
GDLCPDKIRR RSTIIRFTCS DNQVNSRPLF ISAVQDCEYT FSWPTPSACP 1500
VKSNTHDDCQ VTNPSTGHLF DLSSLSGRAG INASYSEKGL VFMSICEENE 1550
NCGPGVGACF GQTRISVGKA SKRLSYKDQV LQLVYENGSP CPSLSDLRYK 1600
SVISFVCRPE AGPTNRPMLI SLDKQTCTLF FSWHTPLACE QATECTVRNG 1650
SSIIDLSPLI HRTGGYEAYD ESEDDTSDTT PDFYINICQP LNPMHGVPCP 1700
AGASVCKVPV DGPPIDIGRV TGPPIFNPVA NEVYLNFESS THCLADRYMN 1750
YTSLITFHCK RGVSMGTPKL IRTNDCDFVF EWETPIVCPD EVKTQGCAVT 1800
DEQLLYSFNL TSLSTSTFKV TRDARTYSIG VCTAAAGLGQ EGCKDGGVCL 1850
LSGNKGASFG RLASMQLDYR HQDEAVILSY VNGDPCPPET DDGEPCVFPF 1900
IYKGKSYDEC VLEGRAKLWC SKTANYDRDH EWGFCRQTNS YRMSAIIFTC 1950
DESEDIGRPQ VFSEDRGCEV TFEWKTKVVC PPKKMECKFV QKHKTYDLRL 2000
LSSLTGSWDF VHEGNSYFIN LCQRVYKGPL DCSERASICK KSATGQVQVL 2050
GLVHTQKLEV IDETVIVTYS KGYPCGGNKT ASSVIELTCA KTVGRPAFKR 2100
FDSVSCTYYF YWYSRAACAV RPQEVTMVNG TLTNPVTGKS FSLGEIYFKL 2150
FSASGDMRTN GDNYLYEIQL SSITSSSYPA CAGANICQVK PNDQHFSRKV 2200
GTSDMTKYYV QDGDLDVVFT SSSKCGKDKT KSVSSTIFFH CDPLVKDGIP 2250
EFSHETADCQ YLFSWYTSAV CPLGVDFEDE SAGPEYKGLS ERSQAVGAVL 2300
SLLLVALTGC LLALLLHKKE RRETVINKLT SCCRRSSGVS YKYSKVSKEE 2350
ETDENETEWL MEEIQVPAPR LGKDGQENGH ITTKAVKAEA LSSLHGDDQD 2400
SEDEVLTVPE VKVHSGRGAE VESSQPLRNP QRKVLKEREG ERLGLVRGEK 2450
ARKGKFRPGQ RKPTAPAKLV SFHDDSDEDL LHI 2483
Length:2,483
Mass (Da):273,815
Last modified:October 1, 1996 - v1
Checksum:i8F64F6189FD05CD1
GO

Sequence conflict

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti10 – 112PS → RP1 Publication
Sequence conflicti13 – 131Missing1 Publication
Sequence conflicti209 – 2091D → V in AAA19568. 1 Publication
Sequence conflicti456 – 4572DT → VS1 Publication
Sequence conflicti1626 – 16316TCTLFF → GSTFFS in CAA42940. 1 Publication
Sequence conflicti1694 – 16952MH → TC in CAA42940. 1 Publication
Sequence conflicti1699 – 16991C → R in CAA42940. 1 Publication
Sequence conflicti1759 – 17591C → Y in AAA19568. 1 Publication
Sequence conflicti2028 – 20281G → V in CAA42940. 1 Publication
Sequence conflicti2032 – 20321C → S in CAA42940. 1 Publication

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L22143
, L22096, L22097, L22098, L22099, L22100, L22101, L22102, L22103, L22104, L22105, L22106, L22107, L22108, L22109, L22110, L22111, L22112, L22113, L22114, L22115, L22116, L22117, L22118, L22119, L22120, L22121, L22122, L22123, L22124, L22125, L22126, L22127, L22128, L22129, L22130, L22131, L22132, L22133, L22134, L22135, L22136, L22137, L22138, L22139, L22140, L22141, L22142 Genomic DNA. Translation: AAA39320.1.
U04710 mRNA. Translation: AAA19568.1.
L06445 Genomic DNA. Translation: AAA37921.1.
L06446 Genomic DNA. Translation: AAA37922.1.
U26348 Genomic DNA. Translation: AAA98844.1.
M58586 Genomic DNA. Translation: AAA39483.1.
X60389 mRNA. Translation: CAA42940.1.
L19500 mRNA. Translation: AAA16037.1.
CCDSiCCDS37436.1.
PIRiA49617.
I48922.
RefSeqiNP_034645.2. NM_010515.2.
UniGeneiMm.26553.

Genome annotation databases

EnsembliENSMUST00000024599; ENSMUSP00000024599; ENSMUSG00000023830.
GeneIDi16004.
KEGGimmu:16004.
UCSCiuc008aky.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L22143
, L22096 , L22097 , L22098 , L22099 , L22100 , L22101 , L22102 , L22103 , L22104 , L22105 , L22106 , L22107 , L22108 , L22109 , L22110 , L22111 , L22112 , L22113 , L22114 , L22115 , L22116 , L22117 , L22118 , L22119 , L22120 , L22121 , L22122 , L22123 , L22124 , L22125 , L22126 , L22127 , L22128 , L22129 , L22130 , L22131 , L22132 , L22133 , L22134 , L22135 , L22136 , L22137 , L22138 , L22139 , L22140 , L22141 , L22142 Genomic DNA. Translation: AAA39320.1 .
U04710 mRNA. Translation: AAA19568.1 .
L06445 Genomic DNA. Translation: AAA37921.1 .
L06446 Genomic DNA. Translation: AAA37922.1 .
U26348 Genomic DNA. Translation: AAA98844.1 .
M58586 Genomic DNA. Translation: AAA39483.1 .
X60389 mRNA. Translation: CAA42940.1 .
L19500 mRNA. Translation: AAA16037.1 .
CCDSi CCDS37436.1.
PIRi A49617.
I48922.
RefSeqi NP_034645.2. NM_010515.2.
UniGenei Mm.26553.

3D structure databases

ProteinModelPortali Q07113.
SMRi Q07113. Positions 43-2159.
ModBasei Search...

Protein-protein interaction databases

BioGridi 200550. 1 interaction.
IntActi Q07113. 4 interactions.
MINTi MINT-200350.

PTM databases

PhosphoSitei Q07113.

Proteomic databases

MaxQBi Q07113.
PaxDbi Q07113.
PRIDEi Q07113.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000024599 ; ENSMUSP00000024599 ; ENSMUSG00000023830 .
GeneIDi 16004.
KEGGi mmu:16004.
UCSCi uc008aky.1. mouse.

Organism-specific databases

CTDi 3482.
MGIi MGI:96435. Igf2r.

Phylogenomic databases

eggNOGi NOG260109.
GeneTreei ENSGT00390000013943.
HOGENOMi HOG000113638.
HOVERGENi HBG000334.
InParanoidi Q07113.
KOi K06564.
OMAi VDCQVTD.
OrthoDBi EOG74BJRG.
PhylomeDBi Q07113.
TreeFami TF328963.

Miscellaneous databases

NextBioi 288798.
PROi Q07113.
SOURCEi Search...

Gene expression databases

ArrayExpressi Q07113.
Bgeei Q07113.
CleanExi MM_IGF2R.
Genevestigatori Q07113.

Family and domain databases

Gene3Di 2.10.10.10. 1 hit.
2.70.130.10. 16 hits.
InterProi IPR000479. CIMR.
IPR000562. FN_type2_col-bd.
IPR013806. Kringle-like.
IPR009011. Man6P_isomerase_rcpt-bd_dom.
[Graphical view ]
Pfami PF00878. CIMR. 14 hits.
PF00040. fn2. 1 hit.
[Graphical view ]
SMARTi SM00059. FN2. 1 hit.
[Graphical view ]
SUPFAMi SSF50911. SSF50911. 16 hits.
SSF57440. SSF57440. 1 hit.
PROSITEi PS00023. FN2_1. 1 hit.
PS51092. FN2_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The mouse insulin-like growth factor II/cation-independent mannose 6-phosphate (IGF-II/MPR) receptor gene: molecular cloning and genomic organization."
    Szebenyi G., Rotwein P.
    Genomics 19:120-129(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  2. "Cloning and sequencing of cDNAs encoding the full-length mouse mannose 6-phosphate/insulin-like growth factor II receptor."
    Ludwig T., Tenscher K., Remmler J., Hoflack B., Lobel P.
    Gene 142:311-312(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Strain: C57BL/6 X CBA.
    Tissue: Liver.
  3. "Maternal-specific methylation of the imprinted mouse Igf2r locus identifies the expressed locus as carrying the imprinting signal."
    Stoger R., Kubicka P., Liu C.G., Kafri T., Razin A., Cedar H., Barlow D.P.
    Cell 73:61-71(1993) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-44 AND 93-106.
    Strain: 129 and C57BL/6.
  4. "Control of insulin-like growth factor-II/mannose 6-phosphate receptor gene transcription by proximal promoter elements."
    Liu Z., Mittanck D.W., Kim S., Rotwein P.
    Mol. Endocrinol. 9:1477-1487(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-44.
    Strain: 129/Sv.
  5. "Differential regulation of mannose 6-phosphate receptors and their ligands during the myogenic development of C2 cells."
    Szebenyi G., Rotwein P.
    J. Biol. Chem. 266:5534-5539(1991) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 435-488.
    Tissue: Liver.
  6. Matzner U.
    Submitted (NOV-1992) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1625-2045.
    Strain: C57BL/6.
  7. "Mutational analysis of the cation-independent mannose 6-phosphate/insulin-like growth factor II receptor. A consensus casein kinase II site followed by 2 leucines near the carboxyl terminus is important for intracellular targeting of lysosomal enzymes."
    Chen H.J., Remmler J., Delaney J.C., Messner D.J., Lobel P.
    J. Biol. Chem. 268:22338-22346(1993) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 2249-2483.
    Strain: C57BL/6 X CBA.
    Tissue: Liver.
  8. Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-2401 AND SER-2476, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Liver.
  9. "Specific phosphopeptide enrichment with immobilized titanium ion affinity chromatography adsorbent for phosphoproteome analysis."
    Zhou H., Ye M., Dong J., Han G., Jiang X., Wu R., Zou H.
    J. Proteome Res. 7:3957-3967(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-2476, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Liver.
  10. "The phagosomal proteome in interferon-gamma-activated macrophages."
    Trost M., English L., Lemieux S., Courcelles M., Desjardins M., Thibault P.
    Immunity 30:143-154(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-2471 AND SER-2476, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  11. "The mouse C2C12 myoblast cell surface N-linked glycoproteome: identification, glycosite occupancy, and membrane orientation."
    Gundry R.L., Raginski K., Tarasova Y., Tchernyshyov I., Bausch-Fluck D., Elliott S.T., Boheler K.R., Van Eyk J.E., Wollscheid B.
    Mol. Cell. Proteomics 8:2555-2569(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-1532.
    Tissue: Myoblast.
  12. "Large scale localization of protein phosphorylation by use of electron capture dissociation mass spectrometry."
    Sweet S.M., Bailey C.M., Cunningham D.L., Heath J.K., Cooper H.J.
    Mol. Cell. Proteomics 8:904-912(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-2401 AND SER-2476, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Embryonic fibroblast.
  13. "Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins."
    Wollscheid B., Bausch-Fluck D., Henderson C., O'Brien R., Bibel M., Schiess R., Aebersold R., Watts J.D.
    Nat. Biotechnol. 27:378-386(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-740; ASN-1532 AND ASN-1750.

Entry informationi

Entry nameiMPRI_MOUSE
AccessioniPrimary (citable) accession number: Q07113
Secondary accession number(s): Q61822, Q6LED1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: July 9, 2014
This is version 130 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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