ID   PAP1_CPRV               Reviewed;         473 AA.
AC   Q070J7;
DT   23-OCT-2007, integrated into UniProtKB/Swiss-Prot.
DT   31-OCT-2006, sequence version 1.
DT   16-JUN-2009, entry version 15.
DE   RecName: Full=Poly(A) polymerase catalytic subunit;
DE            EC=2.7.7.19;
DE   AltName: Full=Poly(A) polymerase large subunit;
DE            Short=PAP-L;
GN   Name=PAPL; OrderedLocusNames=CRV054;
OS   Crocodilepox virus (CRV).
OC   Viruses; dsDNA viruses, no RNA stage; Poxviridae; Chordopoxvirinae;
OC   unclassified Chordopoxvirinae.
OX   NCBI_TaxID=368445;
OH   NCBI_TaxID=8493; Crocodylidae (crocodilians).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16641289; DOI=10.1128/JVI.80.10.4978-4991.2006;
RA   Afonso C.L., Tulman E.R., Delhon G., Lu Z., Viljoen G.J.,
RA   Wallace D.B., Kutish G.F., Rock D.L.;
RT   "Genome of crocodilepox virus.";
RL   J. Virol. 80:4978-4991(2006).
CC   -!- FUNCTION: Polymerase that creates the 3'-poly(A) tail of mRNA's.
CC   -!- CATALYTIC ACTIVITY: ATP + RNA(n) = diphosphate + RNA(n+1).
CC   -!- SUBUNIT: Heterodimer of a large (catalytic) subunit and a small
CC       (regulatory) subunit (By similarity).
CC   -!- SIMILARITY: Belongs to the poxviridae poly(A) polymerase catalytic
CC       subunit family.
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DR   EMBL; DQ356948; ABJ08945.1; -; Genomic_DNA.
DR   RefSeq; YP_784244.1; -.
DR   GeneID; 4363317; -.
DR   BRENDA; 2.7.7.19; 299196.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004652; F:polynucleotide adenylyltransferase activity; IEA:EC.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0006350; P:transcription; IEA:UniProtKB-KW.
DR   InterPro; IPR004976; PolyA_pol_cat_poxviral.
DR   Pfam; PF03296; Pox_polyA_pol; 1.
DR   PIRSF; PIRSF015693; VAC-48L_nuct; 1.
PE   3: Inferred from homology;
KW   ATP-binding; mRNA processing; Nucleotide-binding; Transcription;
KW   Transferase.
FT   CHAIN         1    473       Poly(A) polymerase catalytic subunit.
FT                                /FTId=PRO_0000308929.
FT   ACT_SITE    193    193       By similarity.
FT   ACT_SITE    195    195       By similarity.
SQ   SEQUENCE   473 AA;  54062 MW;  2145D9F31671CCA1 CRC64;
     MNNRELINRY LGKTADQPIY YALFHKVGKI KQILNFDLNV FLKLLLKNRD RFLRENKQPT
     AEIKRRLTHY FTKQHRVRKV GKILSIVEFQ HVIVTTFTRV LGVLTIDNRR VSKMYSSTAI
     LDYAAHEDYV EAMLRSYRVT DGAGPPKGRN KVSDLVGYVI SMLKEYLKRH NKSAFCHGSY
     SLHLLNPAIE YGDIDMLQTN SRTFLINLAF LIYCNTGRVT TMMKIPYLLN YIVMFDEEQA
     HIVDSFQVSQ EIFDRIPKIL INDIYIIDPC VQLLNGIKMF SQVDRLDDLH TKFEKLRARF
     CTLLEYVLYD YDMRIGEGSG AGALRRSRFA YSERVATVEA GALGEDLSPA RWVAFMDNAA
     LDARIGASTR QAADFGPVTN SRFLEEDGCL YGYFSNTLLL TPDGAPHPVS CNALAAHFLM
     YFVMTGAPCK PQLACLLNSL VVPEAREFTL VPRDKKLGDH VILSIDHDVF IDF
//