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Q070J7

- PAP1_CPRVZ

UniProt

Q070J7 - PAP1_CPRVZ

Protein

Poly(A) polymerase catalytic subunit

Gene

PAPL

Organism
Nile crocodilepox virus (isolate Crocodylus niloticus/Zimbabwe/Ume/2001) (CRV)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 34 (01 Oct 2014)
      Sequence version 1 (31 Oct 2006)
      Previous versions | rss
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    Functioni

    Polymerase that creates the 3'-poly(A) tail of mRNA's.

    Catalytic activityi

    ATP + RNA(n) = diphosphate + RNA(n+1).

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei193 – 1931By similarity
    Active sitei195 – 1951By similarity

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. polynucleotide adenylyltransferase activity Source: UniProtKB-EC

    GO - Biological processi

    1. mRNA processing Source: UniProtKB-KW
    2. transcription, DNA-templated Source: UniProtKB-KW

    Keywords - Molecular functioni

    Transferase

    Keywords - Biological processi

    mRNA processing, Transcription

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Poly(A) polymerase catalytic subunit (EC:2.7.7.19)
    Alternative name(s):
    Poly(A) polymerase large subunit
    Short name:
    PAP-L
    Gene namesi
    Name:PAPL
    Ordered Locus Names:CRV054
    OrganismiNile crocodilepox virus (isolate Crocodylus niloticus/Zimbabwe/Ume/2001) (CRV)
    Taxonomic identifieri1289473 [NCBI]
    Taxonomic lineageiVirusesdsDNA viruses, no RNA stagePoxviridaeChordopoxvirinaeCrocodylidpoxvirus
    Virus hostiCrocodylus johnsoni (Australian freshwater crocodile) [TaxID: 184234]
    Crocodylus niloticus (Nile crocodile) (African crocodile) [TaxID: 8501]
    Crocodylus porosus (Saltwater crocodile) (Estuarine crocodile) [TaxID: 8502]
    ProteomesiUP000011300: Genome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 473473Poly(A) polymerase catalytic subunitPRO_0000308929Add
    BLAST

    Interactioni

    Subunit structurei

    Heterodimer of a large (catalytic) subunit and a small (regulatory) subunit.By similarity

    Structurei

    3D structure databases

    ProteinModelPortaliQ070J7.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Family and domain databases

    InterProiIPR024231. Pox_polyA_pol_nucTrfase.
    IPR004976. Poxvirus_polyA_pol_cat.
    IPR024397. Poxvirus_polyA_pol_cat_C.
    IPR024398. Poxvirus_polyA_pol_cat_N.
    [Graphical view]
    PfamiPF03296. Pox_polyA_pol. 1 hit.
    PF12629. Pox_polyA_pol_C. 1 hit.
    PF12630. Pox_polyA_pol_N. 1 hit.
    [Graphical view]
    PIRSFiPIRSF015693. VAC-48L_nuct. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q070J7-1 [UniParc]FASTAAdd to Basket

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    MNNRELINRY LGKTADQPIY YALFHKVGKI KQILNFDLNV FLKLLLKNRD    50
    RFLRENKQPT AEIKRRLTHY FTKQHRVRKV GKILSIVEFQ HVIVTTFTRV 100
    LGVLTIDNRR VSKMYSSTAI LDYAAHEDYV EAMLRSYRVT DGAGPPKGRN 150
    KVSDLVGYVI SMLKEYLKRH NKSAFCHGSY SLHLLNPAIE YGDIDMLQTN 200
    SRTFLINLAF LIYCNTGRVT TMMKIPYLLN YIVMFDEEQA HIVDSFQVSQ 250
    EIFDRIPKIL INDIYIIDPC VQLLNGIKMF SQVDRLDDLH TKFEKLRARF 300
    CTLLEYVLYD YDMRIGEGSG AGALRRSRFA YSERVATVEA GALGEDLSPA 350
    RWVAFMDNAA LDARIGASTR QAADFGPVTN SRFLEEDGCL YGYFSNTLLL 400
    TPDGAPHPVS CNALAAHFLM YFVMTGAPCK PQLACLLNSL VVPEAREFTL 450
    VPRDKKLGDH VILSIDHDVF IDF 473
    Length:473
    Mass (Da):54,062
    Last modified:October 31, 2006 - v1
    Checksum:i2145D9F31671CCA1
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    DQ356948 Genomic DNA. Translation: ABJ08945.1.
    RefSeqiYP_784244.1. NC_008030.1.

    Genome annotation databases

    GeneIDi4363317.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    DQ356948 Genomic DNA. Translation: ABJ08945.1 .
    RefSeqi YP_784244.1. NC_008030.1.

    3D structure databases

    ProteinModelPortali Q070J7.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 4363317.

    Family and domain databases

    InterProi IPR024231. Pox_polyA_pol_nucTrfase.
    IPR004976. Poxvirus_polyA_pol_cat.
    IPR024397. Poxvirus_polyA_pol_cat_C.
    IPR024398. Poxvirus_polyA_pol_cat_N.
    [Graphical view ]
    Pfami PF03296. Pox_polyA_pol. 1 hit.
    PF12629. Pox_polyA_pol_C. 1 hit.
    PF12630. Pox_polyA_pol_N. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF015693. VAC-48L_nuct. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

    Entry informationi

    Entry nameiPAP1_CPRVZ
    AccessioniPrimary (citable) accession number: Q070J7
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 23, 2007
    Last sequence update: October 31, 2006
    Last modified: October 1, 2014
    This is version 34 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programViral Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3