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Q070J7

- PAP1_CPRVZ

UniProt

Q070J7 - PAP1_CPRVZ

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Protein
Poly(A) polymerase catalytic subunit
Gene
PAPL, CRV054
Organism
Nile crocodilepox virus (isolate Crocodylus niloticus/Zimbabwe/Ume/2001) (CRV)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Polymerase that creates the 3'-poly(A) tail of mRNA's.

Catalytic activityi

ATP + RNA(n) = diphosphate + RNA(n+1).

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei193 – 1931 By similarity
Active sitei195 – 1951 By similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. polynucleotide adenylyltransferase activity Source: UniProtKB-EC

GO - Biological processi

  1. mRNA processing Source: UniProtKB-KW
  2. transcription, DNA-templated Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Transferase

Keywords - Biological processi

mRNA processing, Transcription

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Poly(A) polymerase catalytic subunit (EC:2.7.7.19)
Alternative name(s):
Poly(A) polymerase large subunit
Short name:
PAP-L
Gene namesi
Name:PAPL
Ordered Locus Names:CRV054
OrganismiNile crocodilepox virus (isolate Crocodylus niloticus/Zimbabwe/Ume/2001) (CRV)
Taxonomic identifieri1289473 [NCBI]
Taxonomic lineageiVirusesdsDNA viruses, no RNA stagePoxviridaeChordopoxvirinaeCrocodylidpoxvirus
Virus hostiCrocodylus johnsoni (Australian freshwater crocodile) [TaxID: 184234]
Crocodylus niloticus (Nile crocodile) (African crocodile) [TaxID: 8501]
Crocodylus porosus (Saltwater crocodile) (Estuarine crocodile) [TaxID: 8502]
ProteomesiUP000011300: Genome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 473473Poly(A) polymerase catalytic subunit
PRO_0000308929Add
BLAST

Interactioni

Subunit structurei

Heterodimer of a large (catalytic) subunit and a small (regulatory) subunit By similarity.

Structurei

3D structure databases

ProteinModelPortaliQ070J7.

Family & Domainsi

Sequence similaritiesi

Family and domain databases

InterProiIPR024231. Pox_polyA_pol_nucTrfase.
IPR004976. Poxvirus_polyA_pol_cat.
IPR024397. Poxvirus_polyA_pol_cat_C.
IPR024398. Poxvirus_polyA_pol_cat_N.
[Graphical view]
PfamiPF03296. Pox_polyA_pol. 1 hit.
PF12629. Pox_polyA_pol_C. 1 hit.
PF12630. Pox_polyA_pol_N. 1 hit.
[Graphical view]
PIRSFiPIRSF015693. VAC-48L_nuct. 1 hit.

Sequencei

Sequence statusi: Complete.

Q070J7-1 [UniParc]FASTAAdd to Basket

« Hide

MNNRELINRY LGKTADQPIY YALFHKVGKI KQILNFDLNV FLKLLLKNRD    50
RFLRENKQPT AEIKRRLTHY FTKQHRVRKV GKILSIVEFQ HVIVTTFTRV 100
LGVLTIDNRR VSKMYSSTAI LDYAAHEDYV EAMLRSYRVT DGAGPPKGRN 150
KVSDLVGYVI SMLKEYLKRH NKSAFCHGSY SLHLLNPAIE YGDIDMLQTN 200
SRTFLINLAF LIYCNTGRVT TMMKIPYLLN YIVMFDEEQA HIVDSFQVSQ 250
EIFDRIPKIL INDIYIIDPC VQLLNGIKMF SQVDRLDDLH TKFEKLRARF 300
CTLLEYVLYD YDMRIGEGSG AGALRRSRFA YSERVATVEA GALGEDLSPA 350
RWVAFMDNAA LDARIGASTR QAADFGPVTN SRFLEEDGCL YGYFSNTLLL 400
TPDGAPHPVS CNALAAHFLM YFVMTGAPCK PQLACLLNSL VVPEAREFTL 450
VPRDKKLGDH VILSIDHDVF IDF 473
Length:473
Mass (Da):54,062
Last modified:October 31, 2006 - v1
Checksum:i2145D9F31671CCA1
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
DQ356948 Genomic DNA. Translation: ABJ08945.1.
RefSeqiYP_784244.1. NC_008030.1.

Genome annotation databases

GeneIDi4363317.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
DQ356948 Genomic DNA. Translation: ABJ08945.1 .
RefSeqi YP_784244.1. NC_008030.1.

3D structure databases

ProteinModelPortali Q070J7.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 4363317.

Family and domain databases

InterProi IPR024231. Pox_polyA_pol_nucTrfase.
IPR004976. Poxvirus_polyA_pol_cat.
IPR024397. Poxvirus_polyA_pol_cat_C.
IPR024398. Poxvirus_polyA_pol_cat_N.
[Graphical view ]
Pfami PF03296. Pox_polyA_pol. 1 hit.
PF12629. Pox_polyA_pol_C. 1 hit.
PF12630. Pox_polyA_pol_N. 1 hit.
[Graphical view ]
PIRSFi PIRSF015693. VAC-48L_nuct. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Entry informationi

Entry nameiPAP1_CPRVZ
AccessioniPrimary (citable) accession number: Q070J7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 23, 2007
Last sequence update: October 31, 2006
Last modified: May 14, 2014
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3