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Q070J7 (PAP1_CPRVZ) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 33. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Poly(A) polymerase catalytic subunit

EC=2.7.7.19
Alternative name(s):
Poly(A) polymerase large subunit
Short name=PAP-L
Gene names
Name:PAPL
Ordered Locus Names:CRV054
OrganismNile crocodilepox virus (isolate Crocodylus niloticus/Zimbabwe/Ume/2001) (CRV) [Reference proteome]
Taxonomic identifier1289473 [NCBI]
Taxonomic lineageVirusesdsDNA viruses, no RNA stagePoxviridaeChordopoxvirinaeCrocodylidpoxvirus
Virus hostCrocodylus johnsoni (Australian freshwater crocodile) [TaxID: 184234]
Crocodylus niloticus (Nile crocodile) (African crocodile) [TaxID: 8501]
Crocodylus porosus (Saltwater crocodile) (Estuarine crocodile) [TaxID: 8502]

Protein attributes

Sequence length473 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Polymerase that creates the 3'-poly(A) tail of mRNA's.

Catalytic activity

ATP + RNA(n) = diphosphate + RNA(n+1).

Subunit structure

Heterodimer of a large (catalytic) subunit and a small (regulatory) subunit By similarity.

Sequence similarities

Belongs to the poxviridae poly(A) polymerase catalytic subunit family.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 473473Poly(A) polymerase catalytic subunit
PRO_0000308929

Sites

Active site1931 By similarity
Active site1951 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q070J7 [UniParc].

Last modified October 31, 2006. Version 1.
Checksum: 2145D9F31671CCA1

FASTA47354,062
        10         20         30         40         50         60 
MNNRELINRY LGKTADQPIY YALFHKVGKI KQILNFDLNV FLKLLLKNRD RFLRENKQPT 

        70         80         90        100        110        120 
AEIKRRLTHY FTKQHRVRKV GKILSIVEFQ HVIVTTFTRV LGVLTIDNRR VSKMYSSTAI 

       130        140        150        160        170        180 
LDYAAHEDYV EAMLRSYRVT DGAGPPKGRN KVSDLVGYVI SMLKEYLKRH NKSAFCHGSY 

       190        200        210        220        230        240 
SLHLLNPAIE YGDIDMLQTN SRTFLINLAF LIYCNTGRVT TMMKIPYLLN YIVMFDEEQA 

       250        260        270        280        290        300 
HIVDSFQVSQ EIFDRIPKIL INDIYIIDPC VQLLNGIKMF SQVDRLDDLH TKFEKLRARF 

       310        320        330        340        350        360 
CTLLEYVLYD YDMRIGEGSG AGALRRSRFA YSERVATVEA GALGEDLSPA RWVAFMDNAA 

       370        380        390        400        410        420 
LDARIGASTR QAADFGPVTN SRFLEEDGCL YGYFSNTLLL TPDGAPHPVS CNALAAHFLM 

       430        440        450        460        470 
YFVMTGAPCK PQLACLLNSL VVPEAREFTL VPRDKKLGDH VILSIDHDVF IDF 

« Hide

References

[1]"Genome of crocodilepox virus."
Afonso C.L., Tulman E.R., Delhon G., Lu Z., Viljoen G.J., Wallace D.B., Kutish G.F., Rock D.L.
J. Virol. 80:4978-4991(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
DQ356948 Genomic DNA. Translation: ABJ08945.1.
RefSeqYP_784244.1. NC_008030.1.

3D structure databases

ProteinModelPortalQ070J7.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4363317.

Family and domain databases

InterProIPR024231. Pox_polyA_pol_nucTrfase.
IPR004976. Poxvirus_polyA_pol_cat.
IPR024397. Poxvirus_polyA_pol_cat_C.
IPR024398. Poxvirus_polyA_pol_cat_N.
[Graphical view]
PfamPF03296. Pox_polyA_pol. 1 hit.
PF12629. Pox_polyA_pol_C. 1 hit.
PF12630. Pox_polyA_pol_N. 1 hit.
[Graphical view]
PIRSFPIRSF015693. VAC-48L_nuct. 1 hit.
ProtoNetSearch...

Entry information

Entry namePAP1_CPRVZ
AccessionPrimary (citable) accession number: Q070J7
Entry history
Integrated into UniProtKB/Swiss-Prot: October 23, 2007
Last sequence update: October 31, 2006
Last modified: May 14, 2014
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families