Reviewed,
UniProtKB/Swiss-Prot Q06750 (CYSE_BACSU)
Last modified
November 3, 2009.
Version 66.
History...
Clusters with 100%,
90%,
50% identity |
Documents (3) |
Third-party data |
Customize display | text xml rdf/xml gff fasta |
Names and origin
| Protein names | Recommended name: Serine acetyltransferase Short name=SAT EC=2.3.1.30 | ||||||
| Gene names |
| ||||||
| Organism | Bacillus subtilis [Complete proteome] [HAMAP] | ||||||
| Taxonomic identifier | 1423 [NCBI] | ||||||
| Taxonomic lineage | Bacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus |
Protein attributes
| Sequence length | 217 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Evidence at protein level. |
General annotation (Comments)
| Function | Catalyzes the acetylation of serine by acetyl-CoA to produce O-acetylserine (OAS). |
| Catalytic activity | Acetyl-CoA + L-serine = CoA + O-acetyl-L-serine. Ref.4 |
| Enzyme regulation | Inhibited by cysteine. Ref.4 |
| Pathway | Amino-acid biosynthesis; L-cysteine biosynthesis; L-cysteine from L-serine: step 1/2. |
| Subcellular location | Cytoplasm By similarity. |
| Sequence similarities | Belongs to the transferase hexapeptide repeat family. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Amino-acid biosynthesis Cysteine biosynthesis |
| Cellular component | Cytoplasm |
| Domain | Repeat |
| Molecular function | Acyltransferase Transferase |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | cysteine biosynthetic process from serine Inferred from electronic annotation. Source: InterPro |
| Cellular component | cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell |
| Molecular function | serine O-acetyltransferase activity Inferred from electronic annotation. Source: EC |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||
Molecule processing | |||||||
|---|---|---|---|---|---|---|---|
| Chain | 1 – 217 | 217 | Serine acetyltransferase | PRO_0000068665 | |||
Sequences
| ||||||||||||||||||
References
| « Hide 'large scale' references | |
| [1] | "Clustering and co-transcription of the Bacillus subtilis genes encoding the aminoacyl-tRNA synthetases specific for glutamate and for cysteine and the first enzyme for cysteine biosynthesis." Gagnon Y., Breton R., Putzer H., Pelchat M., Grunberg-Manago M., Lapointe J. J. Biol. Chem. 269:7473-7482(1994) [PubMed: 7510287] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. |
| [2] | "Systematic sequencing of the 180 kilobase region of the Bacillus subtilis chromosome containing the replication origin." Ogasawara N., Nakai S., Yoshikawa H. DNA Res. 1:1-14(1994) [PubMed: 7584024] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: 168. |
| [3] | "The complete genome sequence of the Gram-positive bacterium Bacillus subtilis." Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V., Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R., Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S., Bruschi C.V. Danchin A.Nature 390:249-256(1997) [PubMed: 9384377] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 168. |
| [4] | "The CymR regulator in complex with the enzyme CysK controls cysteine metabolism in Bacillus subtilis." Tanous C., Soutourina O., Raynal B., Hullo M.-F., Mervelet P., Gilles A.-M., Noirot P., Danchin A., England P., Martin-Verstraete I. J. Biol. Chem. 283:35551-35560(2008) [PubMed: 18974048] [Abstract] Cited for: CATALYTIC ACTIVITY, ENZYME REGULATION. Strain: 168. |
Cross-references
Sequence databases | |
|---|---|
| L14580 Genomic DNA. Translation: AAA21797.1. D26185 Genomic DNA. Translation: BAA05327.1. AL009126 Genomic DNA. Translation: CAB11869.1. | |
| PIR | B53402. |
| RefSeq | NP_387974.1. |
3D structure databases | |
| ModBase | Search... |
Genome annotation databases | |
| GeneID | 936831. |
| GenomeReviews | Gene locus BSU00930 in contig AL009126_GR. |
| KEGG | bsu:BSU00930. |
| NMPDR | fig|224308.1.peg.93. |
Organism-specific databases | |
| SubtiList | BG10155. cysE. [Micado] |
| CMR | Search... |
Phylogenomic databases | |
| HOGENOM | Q06750. |
| OMA | RHPTIKD. |
Enzyme and pathway databases | |
| BioCyc | BSUB224308:BSU0093-MON. |
| BRENDA | 2.3.1.30. 150. |
Family and domain databases | |
| InterPro | IPR001451. Hexapep_transf. IPR018357. Hexapep_transf_CS. IPR005881. Ser_O-AcTrfase. [Graphical view] |
| Pfam | PF00132. Hexapep. 4 hits. [Graphical view] |
| TIGRFAMs | TIGR01172. cysE. 1 hit. |
| PROSITE | PS00101. HEXAPEP_TRANSFERASES. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | CYSE_BACSU | ||||||||
| Accession | Primary (citable) accession number: Q06750 | ||||||||
| Entry history |
| ||||||||
| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes) | ||||||||
Relevant documents
| Bacillus subtilis Bacillus subtilis (strain 168): entries, gene names and cross-references to SubtiList |
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |

Clusters with


