Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Nuclear receptor subfamily 2 group F member 5

Gene

nr2f5

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Putative receptor that is required in photoreceptor cells precursors during eye development.

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
DNA bindingi51 – 12676Nuclear receptorPROSITE-ProRule annotationAdd
BLAST
Zinc fingeri54 – 7421NR C4-typePROSITE-ProRule annotationAdd
BLAST
Zinc fingeri90 – 11425NR C4-typePROSITE-ProRule annotationAdd
BLAST

GO - Molecular functioni

GO - Biological processi

  • response to retinoic acid Source: ZFIN
  • transcription, DNA-templated Source: UniProtKB-KW
  • visual perception Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Receptor

Keywords - Biological processi

Sensory transduction, Transcription, Transcription regulation, Vision

Keywords - Ligandi

DNA-binding, Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Nuclear receptor subfamily 2 group F member 5
Alternative name(s):
Steroid receptor homolog SVP 46
Gene namesi
Name:nr2f5
Synonyms:svp46
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 16

Organism-specific databases

ZFINiZDB-GENE-990415-253. nr2f5.

Subcellular locationi

  • Nucleus PROSITE-ProRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 403403Nuclear receptor subfamily 2 group F member 5PRO_0000053612Add
BLAST

Proteomic databases

PaxDbiQ06726.

Expressioni

Gene expression databases

BgeeiENSDARG00000033172.
ExpressionAtlasiQ06726. differential.

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000040768.

Structurei

3D structure databases

ProteinModelPortaliQ06726.
SMRiQ06726. Positions 52-132.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Contains 1 nuclear receptor DNA-binding domain.PROSITE-ProRule annotation

Zinc finger

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri54 – 7421NR C4-typePROSITE-ProRule annotationAdd
BLAST
Zinc fingeri90 – 11425NR C4-typePROSITE-ProRule annotationAdd
BLAST

Keywords - Domaini

Zinc-finger

Phylogenomic databases

eggNOGiKOG3575. Eukaryota.
ENOG410XRZC. LUCA.
GeneTreeiENSGT00760000118948.
HOGENOMiHOG000260820.
HOVERGENiHBG005606.
InParanoidiQ06726.
KOiK08702.
OMAiHYNENGP.
OrthoDBiEOG091G0YX6.
PhylomeDBiQ06726.
TreeFamiTF352097.

Family and domain databases

Gene3Di1.10.565.10. 1 hit.
3.30.50.10. 1 hit.
InterProiIPR003068. COUP_TF.
IPR000536. Nucl_hrmn_rcpt_lig-bd.
IPR001723. Nuclear_hrmn_rcpt.
IPR001628. Znf_hrmn_rcpt.
IPR013088. Znf_NHR/GATA.
[Graphical view]
PfamiPF00104. Hormone_recep. 1 hit.
PF00105. zf-C4. 1 hit.
[Graphical view]
PRINTSiPR01282. COUPTNFACTOR.
PR00398. STRDHORMONER.
PR00047. STROIDFINGER.
SMARTiSM00430. HOLI. 1 hit.
SM00399. ZnF_C4. 1 hit.
[Graphical view]
SUPFAMiSSF48508. SSF48508. 1 hit.
PROSITEiPS00031. NUCLEAR_REC_DBD_1. 1 hit.
PS51030. NUCLEAR_REC_DBD_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q06726-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAMVVNQWQE NISADPGSQL QMCSQEPGGT PGTPSGSTPG NDALSGDKIP
60 70 80 90 100
NVDCMVCGDK SSGKHYGQFT CEGCKSFFKR SVRRNLSYTC RGNRDCPIDQ
110 120 130 140 150
HHRNQCQYCR LKKCLKVGMR REAVQRGRMS NSQSSPGQYL SNGSDPYNGQ
160 170 180 190 200
PYLSGFISLL LRAEPYPTSR YGAQCMQSNN LMGIENICEL AARLLFSAVE
210 220 230 240 250
WAKNIPFFPD LQLMDQVALL RMSWSELFVL NAAQCSMPLH VAPLLAAAGL
260 270 280 290 300
HASPMSAERV VAFMDHIRVF QEQVEKLKAL QVDTAEYSCL KSIVLFTSDA
310 320 330 340 350
MGLSDVAHVE SIQEKSQCAL EEYVRNQYPN QPNRFGRLLL RLPSLRIVSS
360 370 380 390 400
PVIEQLFFVR LVGKTPIETL LRDMLLSGSS YNWPYMPVQR DRPISIHYNE

NGP
Length:403
Mass (Da):45,081
Last modified:November 1, 1996 - v1
Checksum:i0848319E2EBEEE62
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X70300 mRNA. Translation: CAA49781.1.
PIRiS35334.
RefSeqiNP_571261.1. NM_131186.1.
UniGeneiDr.22.

Genome annotation databases

EnsembliENSDART00000040769; ENSDARP00000040768; ENSDARG00000033172.
GeneIDi30427.
KEGGidre:30427.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X70300 mRNA. Translation: CAA49781.1.
PIRiS35334.
RefSeqiNP_571261.1. NM_131186.1.
UniGeneiDr.22.

3D structure databases

ProteinModelPortaliQ06726.
SMRiQ06726. Positions 52-132.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7955.ENSDARP00000040768.

Proteomic databases

PaxDbiQ06726.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSDART00000040769; ENSDARP00000040768; ENSDARG00000033172.
GeneIDi30427.
KEGGidre:30427.

Organism-specific databases

CTDi30427.
ZFINiZDB-GENE-990415-253. nr2f5.

Phylogenomic databases

eggNOGiKOG3575. Eukaryota.
ENOG410XRZC. LUCA.
GeneTreeiENSGT00760000118948.
HOGENOMiHOG000260820.
HOVERGENiHBG005606.
InParanoidiQ06726.
KOiK08702.
OMAiHYNENGP.
OrthoDBiEOG091G0YX6.
PhylomeDBiQ06726.
TreeFamiTF352097.

Miscellaneous databases

PROiQ06726.

Gene expression databases

BgeeiENSDARG00000033172.
ExpressionAtlasiQ06726. differential.

Family and domain databases

Gene3Di1.10.565.10. 1 hit.
3.30.50.10. 1 hit.
InterProiIPR003068. COUP_TF.
IPR000536. Nucl_hrmn_rcpt_lig-bd.
IPR001723. Nuclear_hrmn_rcpt.
IPR001628. Znf_hrmn_rcpt.
IPR013088. Znf_NHR/GATA.
[Graphical view]
PfamiPF00104. Hormone_recep. 1 hit.
PF00105. zf-C4. 1 hit.
[Graphical view]
PRINTSiPR01282. COUPTNFACTOR.
PR00398. STRDHORMONER.
PR00047. STROIDFINGER.
SMARTiSM00430. HOLI. 1 hit.
SM00399. ZnF_C4. 1 hit.
[Graphical view]
SUPFAMiSSF48508. SSF48508. 1 hit.
PROSITEiPS00031. NUCLEAR_REC_DBD_1. 1 hit.
PS51030. NUCLEAR_REC_DBD_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiNR2F5_DANRE
AccessioniPrimary (citable) accession number: Q06726
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 15, 1999
Last sequence update: November 1, 1996
Last modified: September 7, 2016
This is version 124 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.