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Q06703 (CDA2_YEAST) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 103. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Chitin deacetylase 2

EC=3.5.1.41
Gene names
Name:CDA2
Ordered Locus Names:YLR308W
ORF Names:L2142.1
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]
Taxonomic identifier559292 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces

Protein attributes

Sequence length312 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Hydrolyzes the N-acetamido groups of N-acetyl-D-glucosamine residues in chitin.

Catalytic activity

Chitin + H2O = chitosan + acetate.

Developmental stage

Expressed exclusively during sporulation.

Sequence similarities

Belongs to the polysaccharide deacetylase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2525 Potential
Chain26 – 312287Chitin deacetylase 2
PRO_0000024827

Amino acid modifications

Glycosylation1421N-linked (GlcNAc...) Potential
Glycosylation1811N-linked (GlcNAc...) Potential
Glycosylation1991N-linked (GlcNAc...) Potential
Glycosylation2461N-linked (GlcNAc...) Potential
Glycosylation2631N-linked (GlcNAc...) Potential

Sequences

Sequence LengthMass (Da)Tools
Q06703 [UniParc].

Last modified November 1, 1996. Version 1.
Checksum: 4033EEFA803F6AF1

FASTA31235,693
        10         20         30         40         50         60 
MRIQLNTIDL QCIIALSCLG QFVHAEANRE DLKQIDFQFP VLERAATKTP FPDWLSAFTG 

        70         80         90        100        110        120 
LKEWPGLDPP YIPLDFIDFS QIPDYKEYDQ NHCDSVPRDS CSFDCHHCTE HDDVYTCSKL 

       130        140        150        160        170        180 
SQTFDDGPSA STTKLLDRLK HNSTFFNLGV NIVQHPDIYQ RMQKEGHLIG SHTWSHVYLP 

       190        200        210        220        230        240 
NVSNEKIIAQ IEWSIWAMNA TGNHTPKWFR PPYGGIDNRV RAITRQFGLQ AVLWDHDTFD 

       250        260        270        280        290        300 
WSLLLNDSVI TEQEILQNVI NWNKSGTGLI LEHDSTEKTV DLAIKINKLI GDDQSTVSHC 

       310 
VGGIDYIKEF LS 

« Hide

References

« Hide 'large scale' references
[1]"The nucleotide sequence of Saccharomyces cerevisiae chromosome XII."
Johnston M., Hillier L.W., Riles L., Albermann K., Andre B., Ansorge W., Benes V., Brueckner M., Delius H., Dubois E., Duesterhoeft A., Entian K.-D., Floeth M., Goffeau A., Hebling U., Heumann K., Heuss-Neitzel D., Hilbert H. expand/collapse author list , Hilger F., Kleine K., Koetter P., Louis E.J., Messenguy F., Mewes H.-W., Miosga T., Moestl D., Mueller-Auer S., Nentwich U., Obermaier B., Piravandi E., Pohl T.M., Portetelle D., Purnelle B., Rechmann S., Rieger M., Rinke M., Rose M., Scharfe M., Scherens B., Scholler P., Schwager C., Schwarz S., Underwood A.P., Urrestarazu L.A., Vandenbol M., Verhasselt P., Vierendeels F., Voet M., Volckaert G., Voss H., Wambutt R., Wedler E., Wedler H., Zimmermann F.K., Zollner A., Hani J., Hoheisel J.D.
Nature 387:87-90(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 204511 / S288c / AB972.
[2]Saccharomyces Genome Database
Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: ATCC 204508 / S288c.
[3]"Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae."
Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F., Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J., Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J. expand/collapse author list , Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D., LaBaer J.
Genome Res. 17:536-543(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[4]"Cloning and expression of two chitin deacetylase genes of Saccharomyces cerevisiae."
Mishra C., Semino C.E., McCreath K.J., de la Vega H., Jones B.J., Specht C.A., Robbins P.W.
Yeast 13:327-336(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: CHARACTERIZATION.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
U17247 Genomic DNA. Translation: AAB67355.1.
AY557951 Genomic DNA. Translation: AAS56277.1.
BK006945 Genomic DNA. Translation: DAA09618.1.
PIRS51440.
RefSeqNP_013411.1. NM_001182196.1.

3D structure databases

ProteinModelPortalQ06703.
SMRQ06703. Positions 109-281.
ModBaseSearch...

Protein-protein interaction databases

DIPDIP-4678N.
MINTMINT-561979.
STRING4932.YLR308W.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiYLR308W; YLR308W; YLR308W.
GeneID851017.
KEGGsce:YLR308W.

Organism-specific databases

CYGDYLR308w.
SGDS000004299. CDA2.

Phylogenomic databases

eggNOGCOG0726.
GeneTreeENSGT00390000014281.
HOGENOMHOG000094344.
KOK01452.
OMAPYIPLDF.
OrthoDBEOG4B5SF4.

Enzyme and pathway databases

BioCycMetaCyc:MONOMER-17650.

Gene expression databases

GenevestigatorQ06703.
GermOnlineYLR308W. Saccharomyces cerevisiae.

Family and domain databases

Gene3D3.20.20.370. 2 hits.
InterProIPR011330. Glyco_hydro/deAcase_b/a-brl.
IPR002509. Polysac_deacetylase.
[Graphical view]
PfamPF01522. Polysacc_deac_1. 1 hit.
[Graphical view]
SUPFAMSSF88713. Glyco_hydro/deAcase_b/a-brl. 1 hit.
ProtoNetSearch...

Other

NextBio967583.

Entry information

Entry nameCDA2_YEAST
AccessionPrimary (citable) accession number: Q06703
Secondary accession number(s): D6VYV2
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1996
Last modified: May 1, 2013
This is version 103 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD

Yeast chromosome XII

Yeast (Saccharomyces cerevisiae) chromosome XII: entries and gene names

SIMILARITY comments

Index of protein domains and families