Q06660 (BC1_TMOV) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Movement protein BC1

Alternative name(s):
Movement protein BL1

Gene names

ORF Names:

BC1, BL1

Organism

Tomato mottle virus (isolate Florida) (ToMoV) [Complete proteome]

Taxonomic identifier

36449 [NCBI]

Taxonomic lineage

Viruses › ssDNA viruses › Geminiviridae › Begomovirus › Tomato mottle virus

Virus host

Nicotiana tabacum (Common tobacco) [TaxID: 4097]

Protein attributes

Sequence length	293 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Movement protein involved in the cell-to-cell and systemic transport of viral genomic DNA. Begomoviruses use 2 proteins to transport their DNA from cell to cell. The nuclear shuttle protein (NSP) shuttles it between nucleus and cytoplasm and the movement protein (MP) probably transports the DNA-NSP complex to the cell periphery and facilitates further movement across the cell wall By similarity.
Subunit structure	Binds to dimeric supercoiled plasmid DNA By similarity.
Subcellular location	Host cell membrane; Peripheral membrane protein; Cytoplasmic side By similarity. Host microsome membrane; Peripheral membrane protein; Cytoplasmic side By similarity. Host endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side By similarity. Note: Found on ER-derived vesicles By similarity.
Post-translational modification	Phosphorylated By similarity.
Sequence similarities	Belongs to the begomovirus movement protein BC1 family.

Ontologies

Keywords
Biological process	Transport
Cellular component	Host cell membrane Host endoplasmic reticulum Host membrane Host microsome Membrane
Ligand	DNA-binding
Molecular function	Viral movement protein
PTM	Phosphoprotein
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	spread of virus in host, cell to cell Inferred from electronic annotation. Source: UniProtKB-KW transport Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	host cell endoplasmic reticulum membrane Inferred from electronic annotation. Source: UniProtKB-SubCell host cell plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell membrane Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	DNA binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 293	293	Movement protein BC1		PRO_0000222259

Sequences

	Sequence		Length	Mass (Da)
	Q06660 [UniParc]. Last modified October 1, 1996. Version 2. Checksum: 571F2AA3D1F5648A	FASTA	293	33,265
	10 20 30 40 50 60 MDSQLVNPPS AFNYIESHRD EYQLSHDLTE IILQFPSTAS QLTARLSRSC MKIDHCVIEY 70 80 90 100 110 120 RQQVPINATG SVIVEIHDKR MTENESLQAS WTFPIRCNID LHYFSASFFS LKDPIPWKLY 130 140 150 160 170 180 YRVCDTNVHQ RTHFAKFKGK LKLSTAKHSV DIPFRAPTVK ILSKQFTDKD VDFSHVDYGK 190 200 210 220 230 240 WERKPIRCAS MSRLGLRGPI EIRPGESWAS RSTIGIGHSD ADSEVENELH PYRHLNRLGT 250 260 270 280 290 GILDPGESAS IVGAQKAESN ITMSMGQLNE LIRTTVHECI NSNCKASQTK SLK

References

[1]	"The nucleotide sequence of tomato mottle virus, a new geminivirus isolated from tomatoes in Florida." Abouzid A.M., Polston J.E., Hiebert E. J. Gen. Virol. 73:3225-3229(1992) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]	Hiebert E. Submitted (APR-1993) to the EMBL/GenBank/DDBJ databases Cited for: SEQUENCE REVISION.

Cross-references

Sequence databases
EMBL GenBank DDBJ	L14461 Genomic DNA. Translation: AAC32419.1.
PIR	JQ1874.
RefSeq	NP_047254.1. NC_001939.1.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	956414.
Family and domain databases
InterPro	IPR000211. Gemini_BL. [Graphical view]
Pfam	PF00845. Gemini_BL1. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

BC1_TMOV

Accession

Primary (citable) accession number: Q06660

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 1, 1994
Last sequence update:	October 1, 1996
Last modified:	April 3, 2013
This is version 45 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Viral Protein Annotation Program