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Q06644 (PMT7_YEAST) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 120. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable dolichyl-phosphate-mannose--protein mannosyltransferase 7

EC=2.4.1.109
Gene names
Name:PMT7
Ordered Locus Names:YDR307W
ORF Names:D9740.4
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]
Taxonomic identifier559292 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces

Protein attributes

Sequence length662 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins By similarity.

Catalytic activity

Dolichyl phosphate D-mannose + protein = dolichyl phosphate + O-D-mannosylprotein.

Subcellular location

Endoplasmic reticulum membrane; Multi-pass membrane protein By similarity.

Sequence similarities

Belongs to the glycosyltransferase 39 family.

Contains 3 MIR domains.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 662662Probable dolichyl-phosphate-mannose--protein mannosyltransferase 7
PRO_0000121497

Regions

Topological domain1 – 2626Lumenal Potential
Transmembrane27 – 4721Helical; Potential
Topological domain48 – 159112Cytoplasmic Potential
Transmembrane160 – 18021Helical; Potential
Topological domain181 – 19515Lumenal Potential
Transmembrane196 – 21621Helical; Potential
Topological domain217 – 23519Cytoplasmic Potential
Transmembrane236 – 25621Helical; Potential
Topological domain257 – 482226Lumenal Potential
Transmembrane483 – 50321Helical; Potential
Topological domain504 – 56562Cytoplasmic Potential
Transmembrane566 – 58621Helical; Potential
Topological domain587 – 61731Lumenal Potential
Transmembrane618 – 63821Helical; Potential
Topological domain639 – 66224Cytoplasmic Potential
Domain289 – 34456MIR 1
Domain359 – 41860MIR 2
Domain432 – 48857MIR 3

Amino acid modifications

Glycosylation3471N-linked (GlcNAc...) Potential

Sequences

Sequence LengthMass (Da)Tools
Q06644 [UniParc].

Last modified November 1, 1997. Version 1.
Checksum: 9083D1DF765A3AE5

FASTA66277,570
        10         20         30         40         50         60 
MKDLRLQGPY RKYIPYNIFQ QCGIGHLKTL DYIFAFLIVI TNFTLIWKSH SSSFWNRPWD 

        70         80         90        100        110        120 
NNSEQELSQL IQFYLDKAFY IHELPPFTIQ FYSIIRRLKI AENLRYVSLF LNSSTLGFLF 

       130        140        150        160        170        180 
LITRRINCSR LISATGLLIL SNWETFRNEG TIISFDSLEW CLFSVVIYSF ISISIAKLGT 

       190        200        210        220        230        240 
TNWFANVITL SISLGLAISS KFIGIVTWAF VILSFVRQFD RLISDVKVTT IQIIKFVILC 

       250        260        270        280        290        300 
LLFVLIIPGS IFIISYSNLL SNFKTDTPQF SKYMSTYFKS YLRGPQVQPS RLYYGSTITL 

       310        320        330        340        350        360 
RHLDSMVGYL ASHDISYPSD VDEQLVALSF EEFAADNEWL IEHPTLNLSF SEVYHADQLI 

       370        380        390        400        410        420 
PVEFGQSIKL RHKSTGKLLR ASTAKPPISE QDYDFQISCT KDSNYEGGMD ERWDVLLIKD 

       430        440        450        460        470        480 
EINNDKKDNA DDKYIKPLQS EIRFYNNGQR CGLLGHDLRL PEWGRFEQEV LCMEYPVIPR 

       490        500        510        520        530        540 
TTFLIDSVQL PVDFQVPMIE YYIGKISSSA EFNHTLSWSQ FLYLFKEYIF KQYKYNYYIK 

       550        560        570        580        590        600 
YGKNKVTFED AFAVEKWPIT LDTDSPVWFN FAWYGSLLSM IIFMCVQCKR MISWNPWTTA 

       610        620        630        640        650        660 
EPSFSIKWEV YNEFGWECIV GWFLHFYIFT MSPHFNLGKK LYFQSFFFSV LCLLESLDCL 


AK 

« Hide

References

« Hide 'large scale' references
[1]"The nucleotide sequence of Saccharomyces cerevisiae chromosome IV."
Jacq C., Alt-Moerbe J., Andre B., Arnold W., Bahr A., Ballesta J.P.G., Bargues M., Baron L., Becker A., Biteau N., Bloecker H., Blugeon C., Boskovic J., Brandt P., Brueckner M., Buitrago M.J., Coster F., Delaveau T. expand/collapse author list , del Rey F., Dujon B., Eide L.G., Garcia-Cantalejo J.M., Goffeau A., Gomez-Peris A., Granotier C., Hanemann V., Hankeln T., Hoheisel J.D., Jaeger W., Jimenez A., Jonniaux J.-L., Kraemer C., Kuester H., Laamanen P., Legros Y., Louis E.J., Moeller-Rieker S., Monnet A., Moro M., Mueller-Auer S., Nussbaumer B., Paricio N., Paulin L., Perea J., Perez-Alonso M., Perez-Ortin J.E., Pohl T.M., Prydz H., Purnelle B., Rasmussen S.W., Remacha M.A., Revuelta J.L., Rieger M., Salom D., Saluz H.P., Saiz J.E., Saren A.-M., Schaefer M., Scharfe M., Schmidt E.R., Schneider C., Scholler P., Schwarz S., Soler-Mira A., Urrestarazu L.A., Verhasselt P., Vissers S., Voet M., Volckaert G., Wagner G., Wambutt R., Wedler E., Wedler H., Woelfl S., Harris D.E., Bowman S., Brown D., Churcher C.M., Connor R., Dedman K., Gentles S., Hamlin N., Hunt S., Jones L., McDonald S., Murphy L.D., Niblett D., Odell C., Oliver K., Rajandream M.A., Richards C., Shore L., Walsh S.V., Barrell B.G., Dietrich F.S., Mulligan J.T., Allen E., Araujo R., Aviles E., Berno A., Carpenter J., Chen E., Cherry J.M., Chung E., Duncan M., Hunicke-Smith S., Hyman R.W., Komp C., Lashkari D., Lew H., Lin D., Mosedale D., Nakahara K., Namath A., Oefner P., Oh C., Petel F.X., Roberts D., Schramm S., Schroeder M., Shogren T., Shroff N., Winant A., Yelton M.A., Botstein D., Davis R.W., Johnston M., Andrews S., Brinkman R., Cooper J., Ding H., Du Z., Favello A., Fulton L., Gattung S., Greco T., Hallsworth K., Hawkins J., Hillier L.W., Jier M., Johnson D., Johnston L., Kirsten J., Kucaba T., Langston Y., Latreille P., Le T., Mardis E., Menezes S., Miller N., Nhan M., Pauley A., Peluso D., Rifkin L., Riles L., Taich A., Trevaskis E., Vignati D., Wilcox L., Wohldman P., Vaudin M., Wilson R., Waterston R., Albermann K., Hani J., Heumann K., Kleine K., Mewes H.-W., Zollner A., Zaccaria P.
Nature 387:75-78(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[2]"The reference genome sequence of Saccharomyces cerevisiae: Then and now."
Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R., Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S., Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.
G3 (Bethesda) 4:389-398(2014) [PubMed] [Europe PMC] [Abstract]
Cited for: GENOME REANNOTATION.
Strain: ATCC 204508 / S288c.
[3]"A global topology map of the Saccharomyces cerevisiae membrane proteome."
Kim H., Melen K., Oesterberg M., von Heijne G.
Proc. Natl. Acad. Sci. U.S.A. 103:11142-11147(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: TOPOLOGY [LARGE SCALE ANALYSIS].
Strain: ATCC 208353 / W303-1A.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
U28374 Genomic DNA. Translation: AAB64743.1.
BK006938 Genomic DNA. Translation: DAA12146.1.
PIRS61193.
RefSeqNP_010593.3. NM_001180615.3.

3D structure databases

ProteinModelPortalQ06644.
SMRQ06644. Positions 289-383.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid32360. 41 interactions.
DIPDIP-5150N.
IntActQ06644. 19 interactions.
MINTMINT-521790.
STRING4932.YDR307W.

Protein family/group databases

CAZyGT39. Glycosyltransferase Family 39.

Proteomic databases

MaxQBQ06644.
PaxDbQ06644.
PeptideAtlasQ06644.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiYDR307W; YDR307W; YDR307W.
GeneID851902.
KEGGsce:YDR307W.

Organism-specific databases

CYGDYDR307w.
SGDS000002715. YDR307W.

Phylogenomic databases

eggNOGCOG1928.
GeneTreeENSGT00740000116239.
KOK00728.
OMAITRRINC.
OrthoDBEOG7KDFKG.

Enzyme and pathway databases

BioCycYEAST:G3O-29866-MONOMER.
BRENDA2.4.1.109. 984.

Gene expression databases

GenevestigatorQ06644.

Family and domain databases

InterProIPR027005. GlyclTrfase_39_like.
IPR016093. MIR_motif.
[Graphical view]
PANTHERPTHR10050. PTHR10050. 1 hit.
PfamPF02815. MIR. 1 hit.
[Graphical view]
SMARTSM00472. MIR. 3 hits.
[Graphical view]
SUPFAMSSF82109. SSF82109. 1 hit.
PROSITEPS50919. MIR. 3 hits.
[Graphical view]
ProtoNetSearch...

Other

NextBio969909.

Entry information

Entry namePMT7_YEAST
AccessionPrimary (citable) accession number: Q06644
Secondary accession number(s): D6VST6
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: June 11, 2014
This is version 120 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Yeast chromosome IV

Yeast (Saccharomyces cerevisiae) chromosome IV: entries and gene names

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD

SIMILARITY comments

Index of protein domains and families