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Protein

Protein BSP1

Gene

BSP1

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Functioni

Cortical patch protein involved in endocytosis. May serve as an adapter to link INP52 and INP53 to the cortical actin cytoskeleton.1 Publication

GO - Molecular functioni

  • protein binding, bridging Source: SGD

GO - Biological processi

  • actin cortical patch localization Source: SGD
  • endocytosis Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Endocytosis

Enzyme and pathway databases

BioCyciYEAST:G3O-34298-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Protein BSP1
Alternative name(s):
Binding of synaptojanin polyphosphoinositide phosphatase domain protein 1
Gene namesi
Name:BSP1
Ordered Locus Names:YPR171W
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome XVI

Organism-specific databases

EuPathDBiFungiDB:YPR171W.
SGDiS000006375. BSP1.

Subcellular locationi

GO - Cellular componenti

  • actin cortical patch Source: SGD
  • cellular bud neck Source: SGD
  • cellular bud tip Source: SGD
  • membrane Source: SGD
  • plasma membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Cytoplasm, Cytoskeleton, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002281371 – 576Protein BSP1Add BLAST576

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei46PhosphoserineCombined sources1
Modified residuei79PhosphoserineCombined sources1
Modified residuei88PhosphoserineCombined sources1
Modified residuei185PhosphoserineCombined sources1
Modified residuei220PhosphoserineCombined sources1
Modified residuei309PhosphoserineCombined sources1
Modified residuei320PhosphoserineCombined sources1

Post-translational modificationi

Phosphorylated by CDC28.1 Publication

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiQ06604.
PRIDEiQ06604.

PTM databases

iPTMnetiQ06604.

Interactioni

Subunit structurei

Interacts with CAP1, RVS167, SLA1, INP52 and INP53. The INP52 and INP53 C-terminal Sac1 domains are required for the binding with BSP1.2 Publications

Binary interactionsi

WithEntry#Exp.IntActNotes
ABP1P158912EBI-37047,EBI-2036
INP52P509424EBI-37047,EBI-28834
LSB3P436037EBI-37047,EBI-22980
RVS167P397435EBI-37047,EBI-14500
SDC25P0CF342EBI-37047,EBI-6315249
SLA1P327906EBI-37047,EBI-17313
YSC84P327936EBI-37047,EBI-24460

GO - Molecular functioni

  • protein binding, bridging Source: SGD

Protein-protein interaction databases

BioGridi36344. 67 interactors.
DIPiDIP-2756N.
IntActiQ06604. 22 interactors.
MINTiMINT-547483.

Structurei

3D structure databases

ProteinModelPortaliQ06604.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

InParanoidiQ06604.
OMAiRSAYNYE.
OrthoDBiEOG092C5J2E.

Sequencei

Sequence statusi: Complete.

Q06604-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTKYERDPEL VNFLSKVEDL NSKRYSNIPS SKPAGEALSP VRSHNSGEYR
60 70 80 90 100
RADMMTGKNV EGCDNLAYRS AYNYEMTFSP KKTHYSLSEL NLERITPRPD
110 120 130 140 150
LEGSASQKEK KFLISEEDYL LLQKLKASQT YNDSNADKNL PSFEKGPRMP
160 170 180 190 200
SRGRPRPREK EIITIQYDFE LPGRADIPSS SSSSSPPPLP TRRDHIKITD
210 220 230 240 250
GNEEKPLLPT RPNKAEVTES PSSRSIKPDA VVPERVKPAP PVSRSTKPAS
260 270 280 290 300
FLSSLEDNKL TKAKSYNSEM ETPKTTVKSS HIDYLDSIQL KPTTLSPTMK
310 320 330 340 350
NKPKPTPPSP PAKRIPRSES FIKSMLNSNL TTTSKPSLPE KPQKLRNANL
360 370 380 390 400
AAHKTKPSIP PKKVELNIVL PELRPVETSP TKQNFENSID LPKLRSSNRN
410 420 430 440 450
IKKEEEDSIP EAIKGIQNLK KTKQQKPAIP QKKSFLTNNS KNTTLKNGDD
460 470 480 490 500
INKLNDEIEA LSLRNNLKKR PPTAPQRKIS LPEALRKVEL MKKSKTEPVL
510 520 530 540 550
ESSNELSINA KLDAIIASRN LRASNTLPEL SGVNTNIATS DKYTTSRDET
560 570
VKETKPLVHP NKNRTRGPRR KLPTRV
Length:576
Mass (Da):64,666
Last modified:November 1, 1996 - v1
Checksum:i7A33A775FCA1F3CD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U25842 Genomic DNA. Translation: AAB68105.1.
BK006949 Genomic DNA. Translation: DAA11588.1.
PIRiS59829.
RefSeqiNP_015497.1. NM_001184268.1.

Genome annotation databases

EnsemblFungiiYPR171W; YPR171W; YPR171W.
GeneIDi856301.
KEGGisce:YPR171W.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U25842 Genomic DNA. Translation: AAB68105.1.
BK006949 Genomic DNA. Translation: DAA11588.1.
PIRiS59829.
RefSeqiNP_015497.1. NM_001184268.1.

3D structure databases

ProteinModelPortaliQ06604.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi36344. 67 interactors.
DIPiDIP-2756N.
IntActiQ06604. 22 interactors.
MINTiMINT-547483.

PTM databases

iPTMnetiQ06604.

Proteomic databases

MaxQBiQ06604.
PRIDEiQ06604.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYPR171W; YPR171W; YPR171W.
GeneIDi856301.
KEGGisce:YPR171W.

Organism-specific databases

EuPathDBiFungiDB:YPR171W.
SGDiS000006375. BSP1.

Phylogenomic databases

InParanoidiQ06604.
OMAiRSAYNYE.
OrthoDBiEOG092C5J2E.

Enzyme and pathway databases

BioCyciYEAST:G3O-34298-MONOMER.

Miscellaneous databases

PROiQ06604.

Family and domain databases

ProtoNetiSearch...

Entry informationi

Entry nameiBSP1_YEAST
AccessioniPrimary (citable) accession number: Q06604
Secondary accession number(s): D6W4H2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 21, 2006
Last sequence update: November 1, 1996
Last modified: November 2, 2016
This is version 118 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Miscellaneous

Present with 704 molecules/cell in log phase SD medium.1 Publication

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  2. Yeast chromosome XVI
    Yeast (Saccharomyces cerevisiae) chromosome XVI: entries and gene names

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.