Q06562 (XYN1_COCCA) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Endo-1,4-beta-xylanase I
Short name=Xylanase I
EC=3.2.1.8

Alternative name(s):
1,4-beta-D-xylan xylanohydrolase 1

Gene names

Name:

XYL1

Organism

Cochliobolus carbonum (Bipolaris zeicola)

Taxonomic identifier

5017 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Fungi › Dikarya › Ascomycota › saccharomyceta › Pezizomycotina › leotiomyceta › dothideomyceta › Dothideomycetes › Pleosporomycetidae › Pleosporales › Pleosporineae › Pleosporaceae › Cochliobolus

Protein attributes

Sequence length	221 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	Major xylan-degrading enzyme. Contributes to the hydrolysis of arabinoxylan, the major component of maize cell-walls.
Catalytic activity	Endohydrolysis of (1->4)-beta-D-xylosidic linkages in xylans.
Pathway	Glycan degradation; xylan degradation.
Subcellular location	Secreted.
Post-translational modification	The N-terminus is blocked.
Sequence similarities	Belongs to the glycosyl hydrolase 11 (cellulase G) family.

Ontologies

Keywords
Biological process	Xylan degradation
Cellular component	Secreted
Domain	Signal
Molecular function	Glycosidase Hydrolase
Technical term	Direct protein sequencing
Gene Ontology (GO)
Biological_process	xylan catabolic process Inferred from electronic annotation. Source: UniProtKB-UniPathway
Cellular_component	extracellular region Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	endo-1,4-beta-xylanase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 30	30	Potential
	Chain	31 – 221	191	Endo-1,4-beta-xylanase I		PRO_0000008003
Sites
	Active site	115	1	Nucleophile By similarity
	Active site	206	1	Proton donor By similarity
Experimental info
	Sequence conflict	81	1	W → I AA sequence Ref.2
	Sequence conflict	107	1	G → A AA sequence Ref.2
	Sequence conflict	131	1	S → W AA sequence Ref.2

Sequences

	Sequence		Length	Mass (Da)
	Q06562 [UniParc]. Last modified February 1, 1995. Version 1. Checksum: 59DBD8983FC5B08C	FASTA	221	23,728
	10 20 30 40 50 60 MVSFTSIITA AVAATGALAA PATDVSLVAR QNTPNGEGTH NGCFWSWWSD GGARATYTNG 70 80 90 100 110 120 AGGSYSVSWG SGGNLVGGKG WNPGTARTIT YSGTYNYNGN SYLAVYGWTR NPLVEYYVVE 130 140 150 160 170 180 NFGTYDPSSQ SQNKGTVTSD GSSYKIAQST RTNQPSIDGT RTFQQYWSVR QNKRSSGSVN 190 200 210 220 MKTHFDAWAS KGMNLGQHYY QIVATEGYFS TGNAQITVNC P

References

[1]	"Cloning and targeted gene disruption of XYL1, a beta 1,4-xylanase gene from the maize pathogen Cochliobolus carbonum." Apel P.C., Panaccione D.G., Holden F.R., Walton J.D. Mol. Plant Microbe Interact. 6:467-473(1993) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: Race 1 / Isolate SB111.
[2]	"Xylanases from the fungal maize pathogen Cochliobolus carbonum." Holden F.R., Walton J.D. Physiol. Mol. Plant Pathol. 40:39-47(1992) [AGRICOLA] [Europe PMC] Cited for: PARTIAL PROTEIN SEQUENCE.

Cross-references

Sequence databases
EMBL GenBank DDBJ	L13596 Genomic DNA. Translation: AAA33024.1.
3D structure databases
ProteinModelPortal	Q06562.
SMR	Q06562. Positions 31-218.
ModBase	Search...
Protein family/group databases
CAZy	GH11. Glycoside Hydrolase Family 11.
mycoCLAP	XYN11A_COCCA.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Enzyme and pathway databases
BRENDA	3.2.1.8. 1551.
UniPathway	UPA00114.
Family and domain databases
Gene3D	2.60.120.180. 1 hit.
InterPro	IPR008985. ConA-like_lec_gl_sf. IPR001137. Glyco_hydro_11. IPR013319. Glyco_hydro_11/12. IPR018208. Glyco_hydro_11_AS. [Graphical view]
Pfam	PF00457. Glyco_hydro_11. 1 hit. [Graphical view]
PRINTS	PR00911. GLHYDRLASE11.
SUPFAM	SSF49899. ConA_like_lec_gl. 1 hit.
PROSITE	PS00776. GLYCOSYL_HYDROL_F11_1. 1 hit. PS00777. GLYCOSYL_HYDROL_F11_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

XYN1_COCCA

Accession

Primary (citable) accession number: Q06562

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 1, 1995
Last sequence update:	February 1, 1995
Last modified:	April 3, 2013
This is version 72 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program