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Reviewed, UniProtKB/Swiss-Prot Q06530 (DHSU_CHRVI)

Last modified November 24, 2009. Version 64. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

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Names and origin

Protein namesRecommended name:
    Sulfide dehydrogenase [flavocytochrome c] flavoprotein chain
    EC=1.8.2.-
Alternative name(s):
    FCSD
    Flavocytochrome c flavoprotein subunit
      Short name=FC
Gene names
Name: fccB
OrganismChromatium vinosum (Allochromatium vinosum)
Taxonomic identifier1049 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Chromatiales › Chromatiaceae › Allochromatium

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Protein attributes

Sequence length431 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level.

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General annotation (Comments)

Subunit structure

Dimer of one cytochrome and one flavoprotein.

Subcellular location

Periplasm.

Post-translational modification

Predicted to be exported by the Tat system. The position of the signal peptide cleavage has been experimentally proven.

Miscellaneous

The active site is a redox-active disulfide bond.

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Ontologies

Keywords
   Cellular componentPeriplasm
   DomainRedox-active center
Signal
   LigandFAD
Flavoprotein
   Molecular functionOxidoreductase
   PTMDisulfide bond
   Technical term3D-structure
Direct protein sequencing
Gene Ontology (GO)
   Biological processoxidation reduction

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentperiplasmic space

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionFAD binding

Inferred from electronic annotation. Source: InterPro

oxidoreductase activity

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

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Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 3030Tat-type signal Ref.2 Ref.3
Chain31 – 431401Sulfide dehydrogenase [flavocytochrome c] flavoprotein chain
PRO_0000021105

Regions

Nucleotide binding70 – 767FAD Potential

Amino acid modifications

Disulfide bond191 ↔ 367Redox-active

Experimental info

Sequence conflict681D → K AA sequence Ref.3

Secondary structure

1 ........................................................................... 431
Helix Strand Turn

Details...

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Sequences

Sequence LengthMass (Da)Tools
Q06530-1 [UniParc].

Last modified December 15, 1998. Version 3.
Checksum: 7F24AE33B83D89BF

FASTA43145,898
        10         20         30         40         50         60 
MTLNRRDFIK TSGAAVAAVG ILGFPHLAFG AGRKVVVVGG GTGGATAAKY IKLADPSIEV 

        70         80         90        100        110        120 
TLIEPNTDYY TCYLSNEVIG GDRKLESIKH GYDGLRAHGI QVVHDSATGI DPDKKLVKTA 

       130        140        150        160        170        180 
GGAEFGYDRC VVAPGIELIY DKIEGYSEEA AAKLPHAWKA GEQTAILRKQ LEDMADGGTV 

       190        200        210        220        230        240 
VIAPPAAPFR CPPGPYERAS QVAYYLKAHK PKSKVIILDS SQTFSKQSQF SKGWERLYGF 

       250        260        270        280        290        300 
GTENAMIEWH PGPDSAVVKV DGGEMMVETA FGDEFKADVI NLIPPQRAGK IAQIAGLTND 

       310        320        330        340        350        360 
AGWCPVDIKT FESSIHKGIH VIGDACIANP MPKSGYSANS QGKVAAAAVV ALLKGEEPGT 

       370        380        390        400        410        420 
PSYLNTCYSI LAPAYGISVA AIYRPNADGS AIESVPDSGG VTPVDAPDWV LEREVQYAYS 

       430 
WYNNIVHDTF G

« Hide

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References

[1]Reinartz M., Trueper H.G., Dahl C.
Submitted (OCT-1997) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 17899 / DSM 180 / D.
[2]"Nucleotide sequence of the heme subunit of flavocytochrome c from the purple phototrophic bacterium, Chromatium vinosum. A 2.6-kilobase pair DNA fragment contains two multiheme cytochromes, a flavoprotein, and a homolog of human ankyrin."
Dolata M.M., van Beeumen J.J., Ambler R.P., Meyer T.E., Cusanovich M.A.
J. Biol. Chem. 268:14426-14431(1993) [PubMed: 8390993] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-125, PROTEIN SEQUENCE OF 31-86; 90-114 AND 119-125.
Strain: ATCC 17899 / DSM 180 / D.
[3]"Covalent structure of the diheme cytochrome subunit and amino-terminal sequence of the flavoprotein subunit of flavocytochrome c from Chromatium vinosum."
van Beeumen J.J., Demol H., Samyn B., Bartsch R.G., Meyer T.E., Dolata M.M., Cusanovich M.A.
J. Biol. Chem. 266:12921-12931(1991) [PubMed: 1649169] [Abstract]
Cited for: PROTEIN SEQUENCE OF 31-78.
[4]"The structure of flavocytochrome c sulfide dehydrogenase from a purple phototrophic bacterium."
Chen Z.-W., Koh M., van Driessche G., van Beeumen J.J., Bartsch R.G., Meyer T.E., Cusanovich M.A., Mathews F.S.
Science 266:430-432(1994) [PubMed: 7939681] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (2.5 ANGSTROMS).

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Cross-references

Sequence databases

AF031149 Genomic DNA. Translation: AAB86576.1.
L13419 Genomic DNA. Translation: AAA23317.1.

3D structure databases

EntryMethodResolution (Å)ChainPositionsPDBsum
1FCDX-ray2.53A/B31-431[»]
ModBaseSearch...

Protein-protein interaction databases

DIPDIP:6169N.

Enzyme and pathway databases

BioCycMetaCyc:MONOMER-12317.

Family and domain databases

InterProIPR016156. FAD/NAD-linked_Rdtase_dimer.
IPR013027. FAD_pyr_nucl-diS_OxRdtase.
IPR015323. FlavoCytC_S_DH_flav-bd.
IPR015904. Sulphide_quinone_reductase.
IPR006311. TAT_signal.
IPR017909. Twin_arg_translocation_Tat.
[Graphical view]
Gene3DG3DSA:3.90.760.10. FlavoCytC_S_DH_flav-bd. 1 hit.
PANTHERPTHR10632. Sulphide_quinone_reductase. 1 hit.
PfamPF09242. FCSD-flav_bind. 1 hit.
PF07992. Pyr_redox_2. 1 hit.
[Graphical view]
TIGRFAMsTIGR01409. TAT_signal_seq. 1 hit.
PROSITEPS51318. TAT. 1 hit.
[Graphical view]
ProtoNetSearch...

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Entry information

Entry nameDHSU_CHRVI
AccessionPrimary (citable) accession number: Q06530
Secondary accession number(s): O31157
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: December 15, 1998
Last modified: November 24, 2009
This is version 64 of the entry and version 3 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

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Relevant documents

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents