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Reviewed, UniProtKB/Swiss-Prot Q06525 (URN1_YEAST)

Last modified June 16, 2009. Version 65. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Binary interactions · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

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Names and origin

Protein namesRecommended name:
    Pre-mRNA-splicing factor URN1
Alternative name(s):
    U2-U5-U6 snRNP, RES complex and NTC-interacting pre-mRNA-splicing factor 1
Gene names
Name: URN1
Ordered Locus Names: YPR152C
OrganismSaccharomyces cerevisiae (Baker's yeast) [Complete proteome]
Taxonomic identifier4932 [NCBI]
Taxonomic lineageEukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces

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Protein attributes

Sequence length465 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceEvidence at protein level.

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General annotation (Comments)

Function

Involved in mRNA processing Probable.

Subcellular location

Nucleus. Ref.3

Miscellaneous

Present with 1310 molecules/cell in log phase SD medium. Ref.4

Sequence similarities

Contains 1 FF domain.

Contains 1 WW domain.

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Ontologies

Keywords
   Biological processmRNA processing
mRNA splicing
   Cellular componentNucleus
Spliceosome
   PTMPhosphoprotein
   Technical term3D-structure
Complete proteome
Gene Ontology (GO)
   Biological processRNA splicing

Inferred from electronic annotation. Source: UniProtKB-KW

mRNA processing

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentspliceosome

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functionprotein binding

Inferred from physical interaction. Source: IntAct

Complete GO annotation...

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Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 465465Pre-mRNA-splicing factor URN1
PRO_0000244477

Regions

Domain1 – 3232WW
Domain214 – 26350FF
Compositional bias119 – 19274Glu-rich

Amino acid modifications

Modified residue1501Phosphoserine Ref.5

Secondary structure

1 ............ 465
Helix Strand Turn

Details...

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Sequences

Sequence LengthMass (Da)Tools
Q06525-1 [UniParc].

Last modified November 1, 1996. Version 1.
Checksum: B32285888B7DB772

FASTA46554,139
        10         20         30         40         50         60 
MRGEWQEFKT PAGKKYYYNK NTKQSRWEKP NLKKGSNLES NAKESQTERK PTFSLELVNG 

        70         80         90        100        110        120 
WHLIIYNDGT KLYFNDDSKE FKNDISQEDD SRCRSLIESL DKEKLVLLIG VARGYTMREE 

       130        140        150        160        170        180 
DIDKILESCN EEIHLFKRNQ DEVERKDEIS EEAGDVKSPL QESHTGLVSG YGSSSGEEDE 

       190        200        210        220        230        240 
EEDEEEDEEN EEQIVNQDIS IIDDLNRIDT DDIDERNIFF ELFDRYKLDK FSTWSLQSKK 

       250        260        270        280        290        300 
IENDPDFYKI RDDTVRESLF EEWCGERSGN ATAEESDSED NSEDDSEVLE PTKYHYLAQI 

       310        320        330        340        350        360 
VANAGTIAPD TIPQDIRKQQ KALYKAYKIK EYIPSKRDQD KFVSQLLFYY KTFDLEQRKE 

       370        380        390        400        410        420 
IFCDCLRDHE RDFTGAVESL RQDKELIDRW QTLLKAPADS SSIEDILLSI EHRCCVSPIV 

       430        440        450        460 
VTEPRYYVVG ILEKTVVWVR WLAAEVGPSS RFTPVGAGNE PINPE

« Hide

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References

« Hide 'large scale' references
[1]"The nucleotide sequence of Saccharomyces cerevisiae chromosome XVI."
Bussey H., Storms R.K., Ahmed A., Albermann K., Allen E., Ansorge W., Araujo R., Aparicio A., Barrell B.G., Badcock K., Benes V., Botstein D., Bowman S., Brueckner M., Carpenter J., Cherry J.M., Chung E., Churcher C.M. expand/collapse author list , Coster F., Davis K., Davis R.W., Dietrich F.S., Delius H., DiPaolo T., Dubois E., Duesterhoeft A., Duncan M., Floeth M., Fortin N., Friesen J.D., Fritz C., Goffeau A., Hall J., Hebling U., Heumann K., Hilbert H., Hillier L.W., Hunicke-Smith S., Hyman R.W., Johnston M., Kalman S., Kleine K., Komp C., Kurdi O., Lashkari D., Lew H., Lin A., Lin D., Louis E.J., Marathe R., Messenguy F., Mewes H.-W., Mirtipati S., Moestl D., Mueller-Auer S., Namath A., Nentwich U., Oefner P., Pearson D., Petel F.X., Pohl T.M., Purnelle B., Rajandream M.A., Rechmann S., Rieger M., Riles L., Roberts D., Schaefer M., Scharfe M., Scherens B., Schramm S., Schroeder M., Sdicu A.-M., Tettelin H., Urrestarazu L.A., Ushinsky S., Vierendeels F., Vissers S., Voss H., Walsh S.V., Wambutt R., Wang Y., Wedler E., Wedler H., Winnett E., Zhong W.-W., Zollner A., Vo D.H., Hani J.
Nature 387:103-105(1997) [PubMed: 9169875] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 204511 / S288c / AB972.
[2]"Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae."
Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F., Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J., Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J. expand/collapse author list , Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D., LaBaer J.
Genome Res. 17:536-543(2007) [PubMed: 17322287] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[3]"Global analysis of protein localization in budding yeast."
Huh W.-K., Falvo J.V., Gerke L.C., Carroll A.S., Howson R.W., Weissman J.S., O'Shea E.K.
Nature 425:686-691(2003) [PubMed: 14562095] [Abstract]
Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
[4]"Global analysis of protein expression in yeast."
Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S.
Nature 425:737-741(2003) [PubMed: 14562106] [Abstract]
Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
[5]"A multidimensional chromatography technology for in-depth phosphoproteome analysis."
Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.
Mol. Cell. Proteomics 7:1389-1396(2008) [PubMed: 18407956] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-150, MASS SPECTROMETRY.
+Additional computationally mapped references.

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Cross-references

Sequence databases

U40829 Genomic DNA. Translation: AAB68289.1.
AY692740 Genomic DNA. Translation: AAT92759.1.
PIRS69038.
RefSeqNP_015478.1.

3D structure databases

EntryMethodResolution (Å)ChainPositionsPDBsum
2JUCNMR-A212-266[»]
ModBaseSearch...

Protein-protein interaction databases

DIPDIP:2017N.
IntActQ06525. 54 interactions.

Genome annotation databases

EnsemblYPR152C. Saccharomyces cerevisiae. [Contig view]
GeneID856275.
GenomeReviewsGene locus YPR152C in contig U00094_GR.
KEGGsce:YPR152C.
NMPDRfig|4932.3.peg.6617.

Organism-specific databases

CYGDYPR152c.
SGDS000006356. URN1.
Yeast-GFPSearch...

Phylogenomic databases

HOGENOMQ06525.
OMAQ06525. EPTKYHY.

Gene expression databases

ArrayExpressQ06525.
GermOnlineYPR152C. Saccharomyces cerevisiae.

Family and domain databases

InterProIPR002713. FF_domain.
IPR001202. WW_Rsp5_WWP.
[Graphical view]
PfamPF01846. FF. 1 hit.
PF00397. WW. 1 hit.
[Graphical view]
SMARTSM00441. FF. 1 hit.
SM00456. WW. 1 hit.
[Graphical view]
PROSITEPS01159. WW_DOMAIN_1. 1 hit.
PS50020. WW_DOMAIN_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Other Resources

NextBio981586.

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Entry information

Entry nameURN1_YEAST
AccessionPrimary (citable) accession number: Q06525
Entry history
Integrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: November 1, 1996
Last modified: June 16, 2009
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectFPAP (Fungal Proteome Annotation Project)

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Relevant documents

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

SIMILARITY comments

Index of protein domains and families

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Binary interactions · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents