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Protein

Autophagy-related protein 33

Gene

ATG33

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Involved in the selective degradation of mitochondria via autophagy during starvation and at post-log phase.2 Publications

GO - Biological processi

  • autophagy of mitochondrion Source: SGD
  • macroautophagy Source: SGD

Keywordsi

Biological processAutophagy

Enzyme and pathway databases

BioCyciYEAST:G3O-32428-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Autophagy-related protein 33
Gene namesi
Name:ATG33
Ordered Locus Names:YLR356W
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome XII

Organism-specific databases

EuPathDBiFungiDB:YLR356W
SGDiS000004348 ATG33

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei10 – 30HelicalSequence analysisAdd BLAST21
Transmembranei52 – 72HelicalSequence analysisAdd BLAST21
Transmembranei78 – 98HelicalSequence analysisAdd BLAST21
Transmembranei172 – 192HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane, Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002472131 – 197Autophagy-related protein 33Add BLAST197

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei127PhosphoserineCombined sources1
Modified residuei129PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiQ06485
PaxDbiQ06485
PRIDEiQ06485

PTM databases

iPTMnetiQ06485

Interactioni

Protein-protein interaction databases

BioGridi31618, 126 interactors
DIPiDIP-4664N
IntActiQ06485, 1 interactor
MINTiQ06485
STRINGi4932.YLR356W

Structurei

3D structure databases

ProteinModelPortaliQ06485
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ATG33 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

GeneTreeiENSGT00530000067118
InParanoidiQ06485
KOiK19717
OMAiHKCHAKS
OrthoDBiEOG092C5526

Sequencei

Sequence statusi: Complete.

Q06485-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSVCLAITKG IAVSSIGLYS GLLASASLIT STTPLEVLTG SLTPTLTTLK
60 70 80 90 100
NAATALGAFA STFFCVSFFG APPSLRHPYL LYGMLVAPLS SFVLGCASNY
110 120 130 140 150
QSRKYSKVSK ESSLFPEDSK LAASELSDSI IDLGEDNHAS ENTPRDGKPA
160 170 180 190
ATTVSKPAEA LHTGPPIHTK NLIAATAIAI VGFVQAVIGV YGEGQFI
Length:197
Mass (Da):20,400
Last modified:November 1, 1996 - v1
Checksum:i4BA9F5CD485FB259
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U19102 Genomic DNA Translation: AAB67748.1
AY558222 Genomic DNA Translation: AAS56548.1
BK006945 Genomic DNA Translation: DAA09660.1
PIRiS51464
RefSeqiNP_013460.1, NM_001182245.1

Genome annotation databases

EnsemblFungiiYLR356W; YLR356W; YLR356W
GeneIDi851070
KEGGisce:YLR356W

Similar proteinsi

Entry informationi

Entry nameiATG33_YEAST
AccessioniPrimary (citable) accession number: Q06485
Secondary accession number(s): D6VYZ4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 25, 2006
Last sequence update: November 1, 1996
Last modified: May 23, 2018
This is version 121 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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