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Q06475 (COX3_SYNY3) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 97. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Cytochrome c oxidase subunit 3

EC=1.9.3.1
Alternative name(s):
Cytochrome aa3 subunit 3
Cytochrome c oxidase polypeptide III
Oxidase aa(3) subunit 3
Gene names
Name:ctaE
Ordered Locus Names:slr1138
OrganismSynechocystis sp. (strain PCC 6803 / Kazusa) [Reference proteome] [HAMAP]
Taxonomic identifier1111708 [NCBI]
Taxonomic lineageBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesSynechocystis

Protein attributes

Sequence length233 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

Subcellular location

Cell membrane; Multi-pass membrane protein.

Sequence similarities

Belongs to the cytochrome c oxidase subunit 3 family.

Ontologies

Keywords
   Cellular componentCell membrane
Membrane
   DomainTransmembrane
Transmembrane helix
   Molecular functionOxidoreductase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processaerobic electron transport chain

Inferred from electronic annotation. Source: InterPro

   Cellular_componentintegral component of membrane

Inferred from electronic annotation. Source: UniProtKB-KW

plasma membrane

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functioncytochrome-c oxidase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 233233Cytochrome c oxidase subunit 3
PRO_0000183891

Regions

Transmembrane62 – 8221Helical; Potential
Transmembrane98 – 11821Helical; Potential
Transmembrane135 – 15521Helical; Potential
Transmembrane172 – 19221Helical; Potential

Experimental info

Sequence conflict1 – 1313MTSPM…ARDFW → MARPPGGFL Ref.1
Sequence conflict114 – 1174SFVM → R in CAA37778. Ref.1

Sequences

Sequence LengthMass (Da)Tools
Q06475 [UniParc].

Last modified November 1, 1997. Version 2.
Checksum: 720A8F794DE17F43

FASTA23326,083
        10         20         30         40         50         60 
MTSPMGPTAR DFWQNSRNSA TIQRLIVSPM QTTALSSDLN STYTPGEAHG HHGHPDLRMF 

        70         80         90        100        110        120 
GVVLFLVAES AIFLGLFTAY LIYRSVMPAW PPEGTPELEL LLPGVNSIIL ISSSFVMHKG 

       130        140        150        160        170        180 
QAAIRNNDNA GLQKWFGITA AMGIIFLAGQ MYEYFHLEMG LTTNLFASCF YVLTGFHGLH 

       190        200        210        220        230 
VTFGLLLILS VLWRSRQPGH YSRTSHFGVE AAELYWHFVD VVWIVLFILV YLL 

« Hide

References

« Hide 'large scale' references
[1]"Characterization of a cta/CDE operon-like genomic region encoding subunits I-III of the cytochrome c oxidase of the cyanobacterium Synechocystis PCC 6803."
Alge D., Peschek G.A.
Biochem. Mol. Biol. Int. 29:511-525(1993) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]"Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions."
Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y., Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S. expand/collapse author list , Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.
DNA Res. 3:109-136(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: PCC 6803 / Kazusa.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
X53746 Genomic DNA. Translation: CAA37778.1.
BA000022 Genomic DNA. Translation: BAA17290.1.
PIRS77443.
RefSeqNP_440610.1. NC_000911.1.
YP_007450493.1. NC_020286.1.

3D structure databases

ProteinModelPortalQ06475.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING1148.slr1138.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAA17290; BAA17290; BAA17290.
GeneID953913.
KEGGsyn:slr1138.
syz:MYO_17210.
PATRIC23838414. VBISynSp132158_0774.

Phylogenomic databases

eggNOGCOG1845.
HOGENOMHOG000086399.
KOK02276.
OMAMEGDRKH.
OrthoDBEOG6SFPBZ.
PhylomeDBQ06475.

Enzyme and pathway databases

BioCycSSP1148:GJOT-723-MONOMER.

Family and domain databases

Gene3D1.20.120.80. 1 hit.
InterProIPR024791. Cyt_c/ubiquinol_Oxase_su3.
IPR000298. Cyt_c_oxidase_su3.
IPR013833. Cyt_c_oxidase_su3_a-hlx.
[Graphical view]
PANTHERPTHR11403. PTHR11403. 1 hit.
PfamPF00510. COX3. 1 hit.
[Graphical view]
SUPFAMSSF81452. SSF81452. 1 hit.
PROSITEPS50253. COX3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCOX3_SYNY3
AccessionPrimary (citable) accession number: Q06475
Secondary accession number(s): P73262
Entry history
Integrated into UniProtKB/Swiss-Prot: June 1, 1994
Last sequence update: November 1, 1997
Last modified: July 9, 2014
This is version 97 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Synechocystis PCC 6803

Synechocystis (strain PCC 6803): entries and gene names

SIMILARITY comments

Index of protein domains and families