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Q06429 (1A11_ARATH) Reviewed, UniProtKB/Swiss-Prot

Last modified November 16, 2011. Version 77. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
1-aminocyclopropane-1-carboxylate synthase-like protein 1
Gene names
Name:ACS1
Synonyms:ACC2
Ordered Locus Names:At3g61510
ORF Names:F2A19.110
OrganismArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifier3702 [NCBI]
Taxonomic lineageEukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis

Protein attributes

Sequence length488 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Subunit structure

Homodimer By similarity.

Tissue specificity

Expressed in young leaves and flowers. Not expressed in roots. Ref.7

Sequence similarities

Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

Caution

Lacks the conserved tripeptide Ser/Thr-Asn-Pro in position 205 necessary for the ACS activity.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 4884881-aminocyclopropane-1-carboxylate synthase-like protein 1
PRO_0000123896

Amino acid modifications

Modified residue2731N6-(pyridoxal phosphate)lysine By similarity

Experimental info

Mutagenesis2051S → TNPS: Restores ACS activity; when expressed in E.coli. Ref.1

Sequences

Sequence LengthMass (Da)Tools
Q06429 [UniParc].

Last modified July 19, 2004. Version 2.
Checksum: 411E049B993DEEE1

FASTA48855,003
        10         20         30         40         50         60 
MSQGACENQL LSKLALSDKH GEASPYFHGW KAYDNNPFHP THNPQGVIQM GLAENQLCSD 

        70         80         90        100        110        120 
LIKEWIKENP QASICTAEGI DSFSDIAVFQ DYHGLKQFRQ AIATFMERAR GGRVRFEAER 

       130        140        150        160        170        180 
VVMSGGATGA NETIMFCLAD PGDAFLVPTP YYAAFDRDLR WRTGVRIIPV ECSSSNNFQI 

       190        200        210        220        230        240 
TKQALESAYL KAQETGIKIK GLIISNPLGT SLDRETLESL VSFINDKQIH LVCDEIYAAT 

       250        260        270        280        290        300 
VFAEPGFISV AEIIQEMYYV NRDLIHIVYS LSKDMGLPGF RVGVVYSYND VVVSCARRMS 

       310        320        330        340        350        360 
SFGLVSSQTQ SFLAAMLSDQ SFVDNFLVEV SKRVAKRHHM FTEGLEEMGI SCLRSNAGLF 

       370        380        390        400        410        420 
VLMDLRHMLK DQTFDSEMAL WRVIINKVKI NVSPGSSFHC SEPGWFRVCF ANMDEDTLQI 

       430        440        450        460        470        480 
ALERIKDFVV GDRANKNKNC NCICNNKREN KKRKSFQKNL KLSLSSMRYE EHVRSPKLMS 


PHSPLLRA

« Hide

References

« Hide 'large scale' references
[1]"Characterization of two members (ACS1 and ACS3) of the 1-aminocyclopropane-1-carboxylate synthase gene family of Arabidopsis thaliana."
Liang X.-W., Oono Y., Shen N.F., Koehler C., Li K., Scolnik P.A., Theologis A.
Gene 167:17-24(1995) [PubMed: 8566772] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA], ABSENCE OF ENZYME ACTIVITY, MUTAGENESIS OF SER-205.
Strain: cv. Columbia.
[2]"Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana."
Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B., Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M., Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V., Choisne N., Artiguenave F. expand/collapse author list , Robert C., Brottier P., Wincker P., Cattolico L., Weissenbach J., Saurin W., Quetier F., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H., Erfle H., Jordan N., Bangert S., Wiedelmann R., Kranz H., Voss H., Holland R., Brandt P., Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A., Toppo S., Simionati B., Conrad A., Hornischer K., Kauer G., Loehnert T.-H., Nordsiek G., Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J., Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwaelder B., Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D., de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E., Monfort A., Argiriou A., Flores M., Liguori R., Vitale D., Mannhaupt G., Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W., Mayer K.F.X., Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M., Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B., Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J., Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C., Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y., Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K., Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.
Nature 408:820-822(2000) [PubMed: 11130713] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Columbia.
[3]The Arabidopsis Information Resource (TAIR)
Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: cv. Columbia.
[4]"Empirical analysis of transcriptional activity in the Arabidopsis genome."
Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G. expand/collapse author list , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
Science 302:842-846(2003) [PubMed: 14593172] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: cv. Columbia.
[5]"The 1-aminocyclopropane-1-carboxylate synthase gene family of Arabidopsis thaliana."
Liang X.-W., Abel S., Keller J.A., Shen N.F., Theologis A.
Proc. Natl. Acad. Sci. U.S.A. 89:11046-11050(1992) [PubMed: 1438312] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE OF 57-88.
[6]"Cloning, genetic mapping, and expression analysis of an Arabidopsis thaliana gene that encodes 1-aminocyclopropane-1-carboxylate synthase."
van der Straeten D., Rodrigues-Pousada R.A., Villarroel R., Hanley S., Goodman H.M., Van Montagu M.
Proc. Natl. Acad. Sci. U.S.A. 89:9969-9973(1992) [PubMed: 1357670] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 100-152.
Strain: cv. C24.
Tissue: Flower.
[7]"Biochemical diversity among the 1-amino-cyclopropane-1-carboxylate synthase isozymes encoded by the Arabidopsis gene family."
Yamagami T., Tsuchisaka A., Yamada K., Haddon W.F., Harden L.A., Theologis A.
J. Biol. Chem. 278:49102-49112(2003) [PubMed: 12968022] [Abstract]
Cited for: TISSUE SPECIFICITY.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		U26542 Genomic DNA. Translation: AAA96006.1.
U26543 mRNA. Translation: AAB60312.1.
AL132962 Genomic DNA. Translation: CAB71081.1.
CP002686 Genomic DNA. Translation: AEE80216.1.
AY133715 mRNA. Translation: AAM91649.1.
Z12615 mRNA. Translation: CAA78261.1.
IPIIPI00520571.
PIRB47199.
T47943.
RefSeqNP_191710.1. NM_116016.1.
UniGeneAt.945.

3D structure databases

ProteinModelPortalQ06429.
SMRQ06429. Positions 10-429.
ModBaseSearch...

Protein-protein interaction databases

IntActQ06429. 3 interactions.
STRINGQ06429.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsAT3G61510.1; AT3G61510.1; AT3G61510.
GeneID825324.
GenomeReviewsGene locus AT3G61510 in contig BA000014_GR.
KEGGath:AT3G61510.
NMPDRfig|3702.1.peg.17526.

Organism-specific databases

GeneFarm4048.
TAIRAt3g61510.

Phylogenomic databases

eggNOGKOG0256.
GeneTreeEPGT00070000028140.
HOGENOMHBG317030.
InParanoidQ06429.
OMAQASICTA.
PhylomeDBQ06429.
ProtClustDBCLSN2915757.

Gene expression databases

ArrayExpressQ06429.
GenevestigatorQ06429.
GermOnlineAT3G61510. Arabidopsis thaliana.

Family and domain databases

InterProIPR001176. ACC_synthase.
IPR004839. Aminotransferase_I/II.
IPR004838. NHTrfase_class1_PyrdxlP-BS.
IPR015424. PyrdxlP-dep_Trfase_major_dom.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
Gene3DG3DSA:3.90.1150.10. PyrdxlP-dep_Trfase_major_sub2. 2 hits.
KOK01762.
PfamPF00155. Aminotran_1_2. 1 hit.
[Graphical view]
PRINTSPR00753. ACCSYNTHASE.
SUPFAMSSF53383. PyrdxlP-dep_Trfase_major. 1 hit.
PROSITEPS00105. AA_TRANSFER_CLASS_1. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry name1A11_ARATH
AccessionPrimary (citable) accession number: Q06429
Secondary accession number(s): Q43368, Q9S9C6
Entry history
Integrated into UniProtKB/Swiss-Prot: July 19, 2004
Last sequence update: July 19, 2004
Last modified: November 16, 2011
This is version 77 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

Arabidopsis thaliana

Arabidopsis thaliana: entries and gene names

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents