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Q06378 (GLNA3_HORVU) Reviewed, UniProtKB/Swiss-Prot

Last modified March 19, 2014. Version 64. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glutamine synthetase

EC=6.3.1.2
Alternative name(s):
Cytoplasmic GS3
Glutamate--ammonia ligase
OrganismHordeum vulgare (Barley)
Taxonomic identifier4513 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBEP cladePooideaeTriticeaeHordeum

Protein attributes

Sequence length356 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Catalytic activity

ATP + L-glutamate + NH3 = ADP + phosphate + L-glutamine.

Subunit structure

Homooctamer By similarity.

Subcellular location

Cytoplasm.

Miscellaneous

In barley, there are distinct isozymes in the chloroplast, and cytoplasm.

Sequence similarities

Belongs to the glutamine synthetase family.

Ontologies

Keywords
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionLigase
Gene Ontology (GO)
   Biological_processglutamine biosynthetic process

Inferred from electronic annotation. Source: InterPro

leaf senescence

Inferred from electronic annotation. Source: EnsemblPlants/Gramene

   Cellular_componentcell wall

Inferred from electronic annotation. Source: EnsemblPlants/Gramene

cytosolic ribosome

Inferred from electronic annotation. Source: EnsemblPlants/Gramene

plasma membrane

Inferred from electronic annotation. Source: EnsemblPlants/Gramene

plasmodesma

Inferred from electronic annotation. Source: EnsemblPlants/Gramene

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

copper ion binding

Inferred from electronic annotation. Source: EnsemblPlants/Gramene

glutamate-ammonia ligase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 356356Glutamine synthetase
PRO_0000153173

Sequences

Sequence LengthMass (Da)Tools
Q06378 [UniParc].

Last modified February 1, 1995. Version 1.
Checksum: 541DB976BFF04BC5

FASTA35639,128
        10         20         30         40         50         60 
MALLTDLLNL DLSGSTEKII AEYIWIGGSG MDLRSKARHL PGPVTHPSKL PKWNYDGSST 

        70         80         90        100        110        120 
GQAPGEDSEV ILYPQAILKD PFREGNNILV MCDCYTPRGE PIPTNKRYNA AKILSNPDVA 

       130        140        150        160        170        180 
KEEPWYGIEQ EYTLLQKDIN WPLGWPVGGF PGPQGPYYCG IGADKSFGRD IVDSHYKACL 

       190        200        210        220        230        240 
FGGVNISGIN GEVMPGQWEF QVGPTVGISA GDQVWVARYI LERITEIAGV VVTFDPKPIP 

       250        260        270        280        290        300 
GDWNGAGAHT NYSTESMRND GGFKVIVDAV EKLKLKHKEH IAAYGEGNER RLTGKHETAD 

       310        320        330        340        350 
INTSSWGVAN RGASVRVGRE TEQNGKGYFE DRRPASNMDP YVVTSMIAQT TILWKP 

« Hide

References

[1]"Isolation and characterization of a cDNA coding for cytoplasmic glutamine synthetase of barley."
Marigo C., Zito F., Casadoro G.
Hereditas 118:281-284(1993) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
X69087 mRNA. Translation: CAA48830.1.
UniGeneHv.331.

3D structure databases

ProteinModelPortalQ06378.
SMRQ06378. Positions 4-355.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Organism-specific databases

GrameneQ06378.

Gene expression databases

GenevestigatorQ06378.

Family and domain databases

Gene3D3.30.590.10. 1 hit.
InterProIPR008147. Gln_synt_beta.
IPR014746. Gln_synth/guanido_kin_cat_dom.
IPR008146. Gln_synth_cat_dom.
IPR027303. Gln_synth_gly_rich_site.
IPR027302. Gln_synth_N_conserv_site.
[Graphical view]
PfamPF00120. Gln-synt_C. 1 hit.
PF03951. Gln-synt_N. 1 hit.
[Graphical view]
SUPFAMSSF54368. SSF54368. 1 hit.
PROSITEPS00180. GLNA_1. 1 hit.
PS00181. GLNA_ATP. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameGLNA3_HORVU
AccessionPrimary (citable) accession number: Q06378
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: February 1, 1995
Last modified: March 19, 2014
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families