Reviewed, UniProtKB/Swiss-Prot Q06365 (ALYP_PSESO)

Names and origin

Protein names

Recommended name:
    Alginate lyase
    EC=4.2.2.3
Alternative name(s):
    Poly(beta-D-mannuronate) lyase
    Poly(mana) alginate lyase

Gene names

Name:	aly
Synonyms:	alyP

Organism

Pseudomonas sp. (strain OS-ALG-9)

Taxonomic identifier

86038 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria

Protein attributes

Sequence length	398 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	Eliminative cleavage of polysaccharides containing beta-D-mannuronate residues to give oligosaccharides with 4-deoxy-alpha-L-erythro-hex-4-enopyranuronosyl groups at their ends.
Sequence similarities	Belongs to the polysaccharide lyase 6 family.

Ontologies

Keywords
Domain	Signal
Molecular function	Lyase
Gene Ontology (GO)
Molecular function	poly(beta-D-mannuronate) lyase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – ?		Potential
	Chain	? – 398		Alginate lyase		PRO_0000024924

Sequences

	Sequence		Length	Mass (Da)
	Q06365-1 [UniParc]. Last modified November 1, 1996. Version 1. Checksum: 67B4DE1D11998F62	FASTA	398	44,512
	10 20 30 40 50 60 MPGDKVIMKS GEWKSQFIHF KGKGTAEKPI TLTAETKGSV LLTGNSNLKI DGEWLVVDGL 70 80 90 100 110 120 SFKNGFSLKD DVVVFTKTTT NSRLTNTSIE NYNPVDKTLD YKWVSLYGHH NRVDHCSITG 130 140 150 160 170 180 KNHQGTTLVV WLDDKPNYHQ IDHNYFGPRP ELGANGGETI RIGTSAFSMN DSYRTVQNNI 190 200 210 220 230 240 FDKCDGEVEI ISIKSGFNKI LNNLFYECAG TVTFRHGNNS EVSNNYFIAN NVTNSGGVRI 250 260 270 280 290 300 IGENQKVYGN YLYKVAGRTL RSAISVMNAY EKPALNDYWQ VKNADIQNNI IVGAREAFVL 310 320 330 340 350 360 GSGKDNDRTL APDGVNISNN YIINPTTLLV TQDEPKNLKM QNNQVEGASI VTGFVKMGND 370 380 390 LQMSDGIWQK KTEIKKPFWL ATAIGPEWKK DHRSFIFK

References

[1]	"Cloning, sequence analysis and expression in Escherichia coli of a gene encoding an alginate lyase from Pseudomonas sp. OS-ALG-9." Maki H., Mori A., Fujiyama K., Kinoshita S., Yoshida T. J. Gen. Microbiol. 139:987-993(1993) [PubMed: 8336113] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	D10336 Genomic DNA. Translation: BAA01182.1.
PIR	S27630.
3D structure databases
ModBase	Search...
Protein family/group databases
CAZy	PL6. Polysaccharide Lyase Family 6.
Family and domain databases
InterPro	IPR006626. PbH1. IPR012334. Pectin_lyas_fold. [Graphical view]
Gene3D	G3DSA:2.160.20.10. Pectin_lyas_fold. 1 hit.
SMART	SM00710. PbH1. 4 hits. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ALYP_PSESO

Accession

Primary (citable) accession number: Q06365

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 15, 1998
Last sequence update:	November 1, 1996
Last modified:	April 14, 2009
This is version 44 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)