Reviewed, UniProtKB/Swiss-Prot Q06216 (PIG1_YEAST)

Names and origin

Protein names

Recommended name:
    Serine/threonine-protein phosphatase 1 regulatory subunit PIG1

Gene names

Name:	PIG1
Ordered Locus Names:	YLR273C
ORF Names:	L9328.2

Organism

Saccharomyces cerevisiae (Baker's yeast) [Complete proteome]

Taxonomic identifier

4932 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces

Protein attributes

Sequence length	648 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

General annotation (Comments)

Function	Regulates the activity of glycogen synthase. It is most probably a regulatory subunit for protein phosphatase type 1.
Sequence similarities	Contains 1 CBM21 (carbohydrate binding type-21) domain.

Ontologies

Keywords
Biological process	Glycogen biosynthesis
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycogen biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW regulation of glycogen biosynthetic process Ref.2 Inferred from genetic interaction. Source: SGD
Cellular component	protein phosphatase type 1 complex Inferred from physical interaction. Source: SGD
Molecular function	protein binding Inferred from physical interaction. Source: IntAct protein phosphatase type 1 regulator activity Ref.2 Inferred from genetic interaction. Source: SGD
Complete GO annotation...

Binary interactions

With	Entry	#Exp.	IntAct	Notes
ERR1	Q12007	1	EBI-13413,EBI-35679

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 648	648	Serine/threonine-protein phosphatase 1 regulatory subunit PIG1		PRO_0000071519
Regions
	Domain	201 – 331	131	CBM21
	Compositional bias	41 – 51	11	Poly-Ser

Sequences

	Sequence		Length	Mass (Da)
	Q06216-1 [UniParc]. Last modified November 1, 1996. Version 1. Checksum: B95853040B225BD7	FASTA	648	74,146
	10 20 30 40 50 60 MPYSHGKKLK PSLKLAKTIS TSSFVSSTTS NSFSPLEDST SASSSTSSSS SGKSVRFAAH 70 80 90 100 110 120 LYTVKKFNTK LAPISISEKA ASNLTRNLHN NAIPLTFPFI GGEDHRYSLD ILDYSDLEYD 130 140 150 160 170 180 NKDVEYDNES DVEDNAMLMH DRSMFIEKEI LCFGEEETFD MADWKLVSNN LNPFKSDYKV 190 200 210 220 230 240 DVTGLEDKIF KYLNGQNIKV HSLELSDPVS YEDICSNNFG NCQIWGLIFV NNLNFEKKIE 250 260 270 280 290 300 IKFTLNNWAD IHYINAHYNK SVTPHVDEFK FIIDISALKL NLISKNLIYT NFFERKTTCL 310 320 330 340 350 360 LNLQFCCRYD VNGFEYRSFY DNNDYKNYEI TISLSAINLN RAVSNSSIFN SNLGPSKMGA 370 380 390 400 410 420 SNAEVTMSKN NENSKKPLRK FIKDTDYYND SPLKHKFYQS FETKAACKTE PVSQTFKAET 430 440 450 460 470 480 IDCEIEPFNY FFEPPDSQTN EDMSDSSYDL SLQDFNYWEF SNHGLGKALA DSDILQFKNY 490 500 510 520 530 540 PKPEPFSRPP IIDDTFTLNT DDRTLGSKTQ KLEDNLAKEW KSAKTRTTLN ETPLHDDEHR 550 560 570 580 590 600 TSFTYTTWNN STDTLMKRKE ERPVESASCS QLSIATIKAE EDLLYQDYIN SGRESSSPEI 610 620 630 640 SPLNTTTSLP FFPGDNMSDS SGEYEERTSL SPNKIHIFRD YFYKSPSP

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The nucleotide sequence of Saccharomyces cerevisiae chromosome XII." Johnston M., Hillier L.W., Riles L., Albermann K., Andre B., Ansorge W., Benes V., Brueckner M., Delius H., Dubois E., Duesterhoeft A., Entian K.-D., Floeth M., Goffeau A., Hebling U., Heumann K., Heuss-Neitzel D., Hilbert H. , Hilger F., Kleine K., Koetter P., Louis E.J., Messenguy F., Mewes H.-W., Miosga T., Moestl D., Mueller-Auer S., Nentwich U., Obermaier B., Piravandi E., Pohl T.M., Portetelle D., Purnelle B., Rechmann S., Rieger M., Rinke M., Rose M., Scharfe M., Scherens B., Scholler P., Schwager C., Schwarz S., Underwood A.P., Urrestarazu L.A., Vandenbol M., Verhasselt P., Vierendeels F., Voet M., Volckaert G., Voss H., Wambutt R., Wedler E., Wedler H., Zimmermann F.K., Zollner A., Hani J., Hoheisel J.D. Nature 387:87-90(1997) [PubMed: 9169871] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 204511 / S288c / AB972.
[2]	"Yeast PIG genes: PIG1 encodes a putative type 1 phosphatase subunit that interacts with the yeast glycogen synthase Gsy2p." Cheng C., Huang D., Roach P.J. Yeast 13:1-8(1997) [PubMed: 9046081] [Abstract] Cited for: PARTIAL NUCLEOTIDE SEQUENCE, CHARACTERIZATION.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBLGenBankDDBJ	U17245 Genomic DNA. Translation: AAB67365.1.
PIR	S51409.
RefSeq	NP_013375.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
DIP	DIP:2918N.
IntAct	Q06216. 7 interactions.
Protein family/group databases
CAZy	CBM21. Carbohydrate-Binding Module Family 21.
Genome annotation databases
Ensembl	YLR273C. Saccharomyces cerevisiae. [Contig view]
GeneID	850979.
GenomeReviews	Gene locus YLR273C in contig Y13138_GR.
KEGG	sce:YLR273C.
NMPDR	fig|4932.3.peg.4390.
Organism-specific databases
CYGD	YLR273c.
SGD	S000004263. PIG1.
Yeast-GFP	Search...
Phylogenomic databases
HOGENOM	Q06216.
Gene expression databases
ArrayExpress	Q06216.
GermOnline	YLR273C. Saccharomyces cerevisiae.
Family and domain databases
InterPro	IPR005036. CBM_21. [Graphical view]
Pfam	PF03370. CBM_21. 1 hit. [Graphical view]
PROSITE	PS51159. CBM21. 1 hit. [Graphical view]
ProtoNet	Search...
Other Resources
NextBio	967489.

Entry information

Entry name

PIG1_YEAST

Accession

Primary (citable) accession number: Q06216

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1997
Last sequence update:	November 1, 1996
Last modified:	June 16, 2009
This is version 56 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

FPAP (Fungal Proteome Annotation Project)