Q06216 (PIG1_YEAST) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Serine/threonine-protein phosphatase 1 regulatory subunit PIG1

Gene names

Name:	PIG1
Ordered Locus Names:	YLR273C
ORF Names:	L9328.2

Organism

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

Taxonomic identifier

559292 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces

Protein attributes

Sequence length	648 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	Regulates the activity of glycogen synthase. It is most probably a regulatory subunit for protein phosphatase type 1.
Sequence similarities	Contains 1 CBM21 (carbohydrate binding type-21) domain.

Ontologies

Keywords
Biological process	Glycogen biosynthesis
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	glycogen biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW regulation of glycogen biosynthetic process Inferred from genetic interaction Ref.4. Source: SGD
Cellular component	protein phosphatase type 1 complex Inferred from physical interaction. Source: SGD
Molecular function	protein phosphatase type 1 regulator activity Inferred from mutant phenotype Ref.4. Source: SGD
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 648	648	Serine/threonine-protein phosphatase 1 regulatory subunit PIG1		PRO_0000071519
Regions
	Domain	201 – 331	131	CBM21
	Compositional bias	41 – 51	11	Poly-Ser
Experimental info
	Sequence conflict	228	1	I → K in AAU09763. Ref.3

Sequences

	Sequence		Length	Mass (Da)
	Q06216 [UniParc]. Last modified November 1, 1996. Version 1. Checksum: B95853040B225BD7	FASTA	648	74,146
	10 20 30 40 50 60 MPYSHGKKLK PSLKLAKTIS TSSFVSSTTS NSFSPLEDST SASSSTSSSS SGKSVRFAAH 70 80 90 100 110 120 LYTVKKFNTK LAPISISEKA ASNLTRNLHN NAIPLTFPFI GGEDHRYSLD ILDYSDLEYD 130 140 150 160 170 180 NKDVEYDNES DVEDNAMLMH DRSMFIEKEI LCFGEEETFD MADWKLVSNN LNPFKSDYKV 190 200 210 220 230 240 DVTGLEDKIF KYLNGQNIKV HSLELSDPVS YEDICSNNFG NCQIWGLIFV NNLNFEKKIE 250 260 270 280 290 300 IKFTLNNWAD IHYINAHYNK SVTPHVDEFK FIIDISALKL NLISKNLIYT NFFERKTTCL 310 320 330 340 350 360 LNLQFCCRYD VNGFEYRSFY DNNDYKNYEI TISLSAINLN RAVSNSSIFN SNLGPSKMGA 370 380 390 400 410 420 SNAEVTMSKN NENSKKPLRK FIKDTDYYND SPLKHKFYQS FETKAACKTE PVSQTFKAET 430 440 450 460 470 480 IDCEIEPFNY FFEPPDSQTN EDMSDSSYDL SLQDFNYWEF SNHGLGKALA DSDILQFKNY 490 500 510 520 530 540 PKPEPFSRPP IIDDTFTLNT DDRTLGSKTQ KLEDNLAKEW KSAKTRTTLN ETPLHDDEHR 550 560 570 580 590 600 TSFTYTTWNN STDTLMKRKE ERPVESASCS QLSIATIKAE EDLLYQDYIN SGRESSSPEI 610 620 630 640 SPLNTTTSLP FFPGDNMSDS SGEYEERTSL SPNKIHIFRD YFYKSPSP

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The nucleotide sequence of Saccharomyces cerevisiae chromosome XII." Johnston M., Hillier L.W., Riles L., Albermann K., Andre B., Ansorge W., Benes V., Brueckner M., Delius H., Dubois E., Duesterhoeft A., Entian K.-D., Floeth M., Goffeau A., Hebling U., Heumann K., Heuss-Neitzel D., Hilbert H. , Hilger F., Kleine K., Koetter P., Louis E.J., Messenguy F., Mewes H.-W., Miosga T., Moestl D., Mueller-Auer S., Nentwich U., Obermaier B., Piravandi E., Pohl T.M., Portetelle D., Purnelle B., Rechmann S., Rieger M., Rinke M., Rose M., Scharfe M., Scherens B., Scholler P., Schwager C., Schwarz S., Underwood A.P., Urrestarazu L.A., Vandenbol M., Verhasselt P., Vierendeels F., Voet M., Volckaert G., Voss H., Wambutt R., Wedler E., Wedler H., Zimmermann F.K., Zollner A., Hani J., Hoheisel J.D. Nature 387:87-90(1997) [PubMed: 9169871] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 204511 / S288c / AB972.
[2]	Saccharomyces Genome Database Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases Cited for: GENOME REANNOTATION. Strain: ATCC 204508 / S288c.
[3]	"Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae." Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F., Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J., Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J. , Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D., LaBaer J. Genome Res. 17:536-543(2007) [PubMed: 17322287] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 204508 / S288c.
[4]	"Yeast PIG genes: PIG1 encodes a putative type 1 phosphatase subunit that interacts with the yeast glycogen synthase Gsy2p." Cheng C., Huang D., Roach P.J. Yeast 13:1-8(1997) [PubMed: 9046081] [Abstract] Cited for: PARTIAL NUCLEOTIDE SEQUENCE, CHARACTERIZATION.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	U17245 Genomic DNA. Translation: AAB67365.1. AY723846 Genomic DNA. Translation: AAU09763.1. BK006945 Genomic DNA. Translation: DAA09586.1.
PIR	S51409.
RefSeq	NP_013375.1. NM_001182160.1.
3D structure databases
ProteinModelPortal	Q06216.
SMR	Q06216. Positions 192-334.
ModBase	Search...
Protein-protein interaction databases
DIP	DIP-2918N.
IntAct	Q06216. 8 interactions.
MINT	MINT-561194.
STRING	Q06216.
Protein family/group databases
CAZy	CBM21. Carbohydrate-Binding Module Family 21.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblFungi	YLR273C; YLR273C; YLR273C.
GeneID	850979.
KEGG	sce:YLR273C.
NMPDR	fig|4932.3.peg.4390.
Organism-specific databases
CYGD	YLR273c.
SGD	S000004263. PIG1.
Phylogenomic databases
eggNOG	fuNOG10770.
OrthoDB	EOG4BK8DC.
Gene expression databases
ArrayExpress	Q06216.
Genevestigator	Q06216.
GermOnline	YLR273C. Saccharomyces cerevisiae.
Family and domain databases
InterPro	IPR005036. CBM_21. [Graphical view]
Pfam	PF03370. CBM_21. 1 hit. [Graphical view]
PROSITE	PS51159. CBM21. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	967489.

Entry information

Entry name

PIG1_YEAST

Accession

Primary (citable) accession number: Q06216
Secondary accession number(s): D6VYS0, E9P964

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1997
Last sequence update:	November 1, 1996
Last modified:	December 14, 2011
This is version 76 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program