Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Diacylglycerol kinase

Gene

dgkA

Organism
Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium meliloti)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Recycling of diacylglycerol produced during cyclic beta-1,2-glucan biosynthesis.

Catalytic activityi

ATP + 1,2-diacyl-sn-glycerol = ADP + 1,2-diacyl-sn-glycerol 3-phosphate.

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. diacylglycerol kinase activity Source: UniProtKB-EC

GO - Biological processi

  1. phospholipid biosynthetic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Biological processi

Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciSMEL266834:GJF6-1931-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Diacylglycerol kinase (EC:2.7.1.107)
Short name:
DAGK
Alternative name(s):
Diglyceride kinase
Short name:
DGK
Gene namesi
Name:dgkA
Ordered Locus Names:R01883
ORF Names:SMc04213
OrganismiRhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium meliloti)
Taxonomic identifieri266834 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeSinorhizobium/Ensifer groupSinorhizobium
ProteomesiUP000001976: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 4646CytoplasmicSequence AnalysisAdd
BLAST
Transmembranei47 – 6216HelicalSequence AnalysisAdd
BLAST
Transmembranei66 – 8217HelicalSequence AnalysisAdd
BLAST
Topological domaini83 – 10927CytoplasmicSequence AnalysisAdd
BLAST
Transmembranei110 – 13324HelicalSequence AnalysisAdd
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 137137Diacylglycerol kinasePRO_0000195267Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi266834.SMc04213.

Structurei

3D structure databases

ProteinModelPortaliQ06119.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG0818.
HOGENOMiHOG000014819.
KOiK00901.
OMAiIACFLDV.
OrthoDBiEOG60W7XM.

Family and domain databases

InterProiIPR000829. Diacylglycerol_kinase_prok.
[Graphical view]
PfamiPF01219. DAGK_prokar. 1 hit.
[Graphical view]
PROSITEiPS01069. DAGK_PROKAR. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q06119-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MDAKNTTSRN GTAAPVHKHR GIRHLFAAAS YSFGGAKRLI GEAAFRHELI
60 70 80 90 100
AFAVAMVAFM IVGANLFQYV AMAILFLLMM AFEAINTAIE EIVDRVSPEI
110 120 130
SEMGRNAKDL GSFACLCLIL ANAAYALYVI FLARFLG
Length:137
Mass (Da):14,892
Last modified:February 1, 1994 - v1
Checksum:i0BE65269F1145BC5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M94085 Genomic DNA. Translation: AAA26257.1.
AL591688 Genomic DNA. Translation: CAC46462.1.
PIRiS27659.
RefSeqiNP_385989.1. NC_003047.1.
WP_010969538.1. NC_003047.1.

Genome annotation databases

EnsemblBacteriaiCAC46462; CAC46462; SMc04213.
GeneIDi1233548.
KEGGisme:SMc04213.
PATRICi23633175. VBISinMel96828_3326.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M94085 Genomic DNA. Translation: AAA26257.1.
AL591688 Genomic DNA. Translation: CAC46462.1.
PIRiS27659.
RefSeqiNP_385989.1. NC_003047.1.
WP_010969538.1. NC_003047.1.

3D structure databases

ProteinModelPortaliQ06119.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi266834.SMc04213.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAC46462; CAC46462; SMc04213.
GeneIDi1233548.
KEGGisme:SMc04213.
PATRICi23633175. VBISinMel96828_3326.

Phylogenomic databases

eggNOGiCOG0818.
HOGENOMiHOG000014819.
KOiK00901.
OMAiIACFLDV.
OrthoDBiEOG60W7XM.

Enzyme and pathway databases

BioCyciSMEL266834:GJF6-1931-MONOMER.

Family and domain databases

InterProiIPR000829. Diacylglycerol_kinase_prok.
[Graphical view]
PfamiPF01219. DAGK_prokar. 1 hit.
[Graphical view]
PROSITEiPS01069. DAGK_PROKAR. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Identification of the diacylglycerol kinase structural gene of Rhizobium meliloti 1021."
    Miller K.J., McKinstry M.W., Hunt W.P., Nixon B.T.
    Mol. Plant Microbe Interact. 5:363-371(1992) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: 1021.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 1021.
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 1021.

Entry informationi

Entry nameiKDGL_RHIME
AccessioniPrimary (citable) accession number: Q06119
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1994
Last sequence update: February 1, 1994
Last modified: January 7, 2015
This is version 92 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.