Q06088 (TYDC4_PETCR) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Tyrosine decarboxylase 4
EC=4.1.1.25

Gene names

Name:

TYRDC-4

Organism

Petroselinum crispum (Parsley) (Petroselinum hortense)

Taxonomic identifier

4043 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Viridiplantae › Streptophyta › Streptophytina › Embryophyta › Tracheophyta › Euphyllophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › asterids › campanulids › Apiales › Apiineae › Apiaceae › Apioideae › apioid superclade › Apieae › Petroselinum

Protein attributes

Sequence length	508 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Catalytic activity	L-tyrosine = tyramine + CO2.
Cofactor	Pyridoxal phosphate.
Subunit structure	Homodimer By similarity.
Sequence similarities	Belongs to the group II decarboxylase family.

Ontologies

Keywords
Ligand	Pyridoxal phosphate
Molecular function	Decarboxylase Lyase
Gene Ontology (GO)
Biological_process	cellular amino acid metabolic process Inferred from electronic annotation. Source: InterPro
Molecular_function	pyridoxal phosphate binding Inferred from electronic annotation. Source: InterPro tyrosine decarboxylase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 508	508	Tyrosine decarboxylase 4		PRO_0000146998
Amino acid modifications
	Modified residue	318	1	N6-(pyridoxal phosphate)lysine By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q06088 [UniParc]. Last modified November 1, 1995. Version 1. Checksum: F626236B8EF39B29	FASTA	508	56,771
	10 20 30 40 50 60 MGSIDNLMAQ KLTSQFPMNT LEPEEFRRQG HLMIDFLADY YRKVENYPVR SQVSPGYLRE 70 80 90 100 110 120 ILPESAPYNP ESLETILQDV QTKIIPGITH WQSPNFFAYF PSSGSTAGFL GEMLSTGFNV 130 140 150 160 170 180 VGFNWMVSPA ATELENVVTD WFGKMLQLPK SFLFSGGGGG VLQGTTCEAI LCTLVAARDK 190 200 210 220 230 240 NLRQHGMDNI GKLVVYCSDQ THSALQKAAK IAGIDPKNFR AIETTKSSNF KLCPKRLESA 250 260 270 280 290 300 ILYDLQNGLI PLYLCATVGT TSSTTVDPLP ALTEVAKKYD LWVHVDAAYA GSACICPEFR 310 320 330 340 350 360 QYLDGVENAD SFSLNAHKWF LTTLDCCCLW VRDPSALIKS LSTYPEFLKN NASETNKVVD 370 380 390 400 410 420 YKDWQIMLSR RFRALKLWFV LRSYGVGQLR EFIRGHVGMA KYFEGLVGLD KRFEVVAPRL 430 440 450 460 470 480 FSMVCFRIKP SAMIGKNDED EVNEINRKLL ESVNDSGRIY VSHTVLGGIY VIRFAIGGTL 490 500 TDINHVSAAW KVLQDHADAL LDEAFTAN

References

[1]	"A pathogen-responsive gene of parsley encodes tyrosine decarboxylase." Kawalleck P., Keller H., Hahlbrock K., Scheel D., Somssich I.E. J. Biol. Chem. 268:2189-2194(1993) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	M95685 mRNA. Translation: AAA33863.1.
3D structure databases
ProteinModelPortal	Q06088.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
Gene3D	3.40.640.10. 1 hit. 3.90.1150.10. 1 hit.
InterPro	IPR010977. Aromatic_deC. IPR002129. PyrdxlP-dep_de-COase. IPR015424. PyrdxlP-dep_Trfase. IPR015421. PyrdxlP-dep_Trfase_major_sub1. IPR015422. PyrdxlP-dep_Trfase_major_sub2. IPR021115. Pyridoxal-P_BS. [Graphical view]
Pfam	PF00282. Pyridoxal_deC. 1 hit. [Graphical view]
PRINTS	PR00800. YHDCRBOXLASE.
SUPFAM	SSF53383. PyrdxlP-dep_Trfase_major. 1 hit.
PROSITE	PS00392. DDC_GAD_HDC_YDC. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

TYDC4_PETCR

Accession

Primary (citable) accession number: Q06088

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1995
Last sequence update:	November 1, 1995
Last modified:	April 3, 2013
This is version 61 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program